Erythropoietin: Friend and foe!

Acta Physiologica

Volumn 212, Issue 2, 2014, Pages 125-127

  Brugniaux, J V ^a  

^a UNIVERSITY OF GLAMORGAN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; HYDROXYL RADICAL; ANTIOXIDANT;

ALTITUDE DISEASE; ARTERIAL OXYGEN SATURATION; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN ISCHEMIA; CELL DAMAGE; CEREBROVASCULAR ACCIDENT; EDITORIAL; ERYTHROCYTE; ERYTHROPOIESIS; GENE EXPRESSION; HUMAN; HYPOXEMIA; HYPOXIA; IN VITRO STUDY; IRON CHELATION; KIDNEY FAILURE; NEUROPROTECTION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; ANOXIA; MALE; METABOLISM; PHYSIOLOGY;

ANOXIA; ANTIOXIDANTS; ERYTHROPOIETIN; HUMANS; MALE; OXIDATIVE STRESS;

EID: 84912070698     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12349     Document Type: Editorial

References (14)

1. Bailey, D.M., McEneny, J., Mathieu-Costello, O., Henry, R.R., James, P.E., McCord, J.M., Pietri, S., Young, I.S. & Richardson, R.S. 2010. Sedentary aging increases resting and exercise-induced intramuscular free radical formation. J Appl Physiol 109, 449-456.
2. Bailey, D.M., Rimoldi, S.F., Rexhaj, E., Pratali, L., Salinas Salmon, C., Villena, M., McEneny, J., Young, I.S., Nicod, P., Allemann, Y., Scherrer, U. & Sartori, C. 2013. Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia. Chest 143, 444-451.
3. Bailey, D.M., Lundby, C., Berg, R.M., Taudorf, S., Rahmouni, H., Gutowski, M., Mulholland, C.W., Sullivan, J.L., Swenson, E.R., McEneny, J., Young, I.S., Pedersen, B.K., Moller, K., Pietri, S. & Culcasi, M. 2014. On the antioxidant properties of erythropoietin and its association with the oxidative-nitrosative stress response to hypoxia in humans. Acta Physiol (Oxf). Doi: 10.1111/apha.12313.
4. Brines, M.L., Ghezzi, P., Keenan, S., Agnello, D., de Lanerolle, N.C., Cerami, C., Itri, L.M. & Cerami, A. 2000. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A 97, 10526-10531.
5. Brugniaux, J. & Pichon, A. 2007. Determining an erythropoietin threshold is not sufficient for accelerating erythrocyte production. Eur J Appl Physiol 99, 325-326; author reply 327-328.
6. Brugniaux, J.V., Schmitt, L., Robach, P., Nicolet, G., Fouillot, J.P., Moutereau, S., Lasne, F., Pialoux, V., Saas, P., Chorvot, M.C., Cornolo, J., Olsen, N.V. & Richalet, J.P. 2006. Eighteen days of "living high, training low" stimulate erythropoiesis and enhance aerobic performance in elite middle-distance runners. J Appl Physiol 100, 203-211.
7. Brugniaux, J.V., Pialoux, V., Foster, G.E., Duggan, C.T., Eliasziw, M., Hanly, P.J. & Poulin, M.J. 2011. Effects of intermittent hypoxia on Epo, soluble Epo receptor and ventilation in humans. Eur Respir J 37, 880-887.
8. Bunn, H.F. 2013. Erythropoietin. Cold Spring Harb Perspect Med 3, a011619.
9. Ehrenreich, H., Weissenborn, K., Prange, H., Schneider, D., Weimar, C., Wartenberg, K., Schellinger, P.D., Bohn, M., Becker, H., Wegrzyn, M. et al. 2009. Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke 40, e647-e656.
10. Gassmann, M., Tissot van Patot, M. & Soliz, J. 2009. The neuronal control of hypoxic ventilation: erythropoietin and sexual dimorphism. Ann N Y Acad Sci 1177, 151-161.
11. Jelkmann, W. & Lundby, C. 2011. Blood doping and its detection. Blood 118, 2395-2404.
12. Leon-Velarde, F., Monge, C.C., Vidal, A., Carcagno, M., Criscuolo, M. & Bozzini, C.E. 1991. Serum immunoreactive erythropoietin in high altitude natives with and without excessive erythrocytosis. Exp Hematol 19, 257-260.
13. Pialoux, V., Brugniaux, J.V., Fellmann, N., Richalet, J.P., Robach, P., Schmitt, L., Coudert, J. & Mounier, R. 2009a. Oxidative stress and HIF-1 alpha modulate hypoxic ventilatory responses after hypoxic training on athletes. Respir Physiol Neurobiol 167, 217-220.
14. Pialoux, V., Hanly, P.J., Foster, G.E., Brugniaux, J.V., Beaudin, A.E., Hartmann, S.E., Pun, M., Duggan, C.T. & Poulin, M.J. 2009b. Effects of exposure to intermittent hypoxia on oxidative stress and acute hypoxic ventilatory response in humans. Am J Respir Crit Care Med 180, 1002-1009.