Brief report: Are autistic-behaviors in children related to prenatal vitamin use and maternal whole blood folate concentrations?

Journal of Autism and Developmental Disorders

Volumn 44, Issue 10, 2014, Pages 2602-2607

  Braun, Joseph M ^a   Froehlich, Tanya ^b   Kalkbrenner, Amy ^c   Pfeiffer, Christine M ^d   Fazili, Zia ^d   Yolton, Kimberly ^b   Lanphear, Bruce P ^e,f  

^a BROWN UNIVERSITY   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^d NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^e SIMON FRASER UNIVERSITY   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Autism spectrum disorders; Pregnancy; Prenatal vitamins; Folate

Indexed keywords

FOLIC ACID; VITAMIN;

ADULT; ARTICLE; ASSESSMENT OF HUMANS; AUTISM; BRAIN DEVELOPMENT; CHILD; COHORT ANALYSIS; FEMALE; FOLIC ACID BLOOD LEVEL; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MATERNAL BLOOD; MOTHER CHILD RELATION; PRENATAL PERIOD; PROSPECTIVE STUDY; SECOND TRIMESTER PREGNANCY; SOCIAL RESPONSIVENESS SCALE; VITAMIN INTAKE; ADOLESCENT; BLOOD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DIET SUPPLEMENTATION; MATERNAL WELFARE; PREGNANCY; PRENATAL CARE; PRESCHOOL CHILD; PROCEDURES; RESEARCH; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; COHORT STUDIES; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; FOLLOW-UP STUDIES; HUMANS; MATERNAL WELFARE; PREGNANCY; PRENATAL CARE; PROSPECTIVE STUDIES; RESEARCH REPORT; VITAMINS; YOUNG ADULT;

EID: 84912029503     PISSN: 01623257     EISSN: 15733432     Source Type: Journal    
DOI: 10.1007/s10803-014-2114-x     Document Type: Article

References (28)

1. Anjos, T., Altmae, S., et al. (2013). Nutrition and neurodevelopment in children: Focus on NUTRIMENTHE project. European Journal of Nutrition, 52(8), 1825–1842.
2. Beck, A. T., Steer, R. A., et al. (1996). Beck depression inventory— 2nd edition (BDI-II). San Antonio: The Psychological Corporation.
3. Bellinger, D. C. (2004). Assessing environmental neurotoxicant exposures and child neurobehavior: confounded by confounding? Epidemiology, 15(4), 383–384.
4. Braun, J. M., Daniels, J. L., et al. (2010a). Prenatal environmental tobacco smoke exposure and early childhood body mass index. Paediatric and Perinatal Epidemiology, 24(6), 524–534.
5. Braun, J. M., Daniels, J. L., et al. (2010b). A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight. Environ Health, 9, 53.
6. Braun, J. M., Kalkbrenner, A. E., et al. (2011). Impact of early-life bisphenol a exposure on behavior and executive function in children. Pediatrics, 128(5), 873–882.
7. Constantino, J. (2005). Social Responsiveness Scale. Los Angeles, CA: Western Psychological Services.
8. De-Regil, L. M., Fernandez-Gaxiola, A. C., et al. (2010). Effects and safety of periconceptional folate supplementation for preventing birth defects. Cochrane Database Systematic Review, 10, CD007950.
9. Erkkola, M., Karppinen, M., et al. (2001). Validity and reproducibility of a food frequency questionnaire for pregnant Finnish women. American Journal of Epidemiology, 154(5), 466–476.
10. Fazili, Z., & Pfeiffer, C. M. (2004). Measurement of folates in serum and conventionally prepared whole blood lysates: Application of an automated 96-well plate isotope-dilution tandem mass spectrometry method. Clinical Chemistry, 50(12), 2378–2381.
11. Fitzmaurice, G. M., Laird, N. M., et al. (2004). Applied longitudinal data analysis. Hoboken: Wiley.
12. Hus, V., Bishop, S., et al. (2013). Factors influencing scores on the Social Responsiveness Scale. Journal of Child Psychology and Psychiatry, 54(2), 216–224.
13. Jones, R. M., & Lord, C. (2013). Diagnosing autism in neurobiological research studies. Behavioural Brain Research, 251, 113–124.
14. Lacher, D., J. Hughes, et al. (2010). Biological variation of laboratory analytes based on the 1999–2002 National Health and Nutrition Examination Survey. National health statistics reports. Hyattsville, MD, National Center for Health Statistic 21.
15. Leenders, M., Ros, M. M., et al. (2013). Reliability of selected antioxidants and compounds involved in one-carbon metabolism in two Dutch cohorts. Nutrition and Cancer, 65(1), 17–24.
16. Reiersen, A. M., Constantino, J. N., et al. (2007). Autistic traits in a population-based ADHD twin sample. Journal of Child Psychology and Psychiatry, 48(5), 464–472.
17. Roth, C., Magnus, P., et al. (2011). Folic acid supplements in pregnancy and severe language delay in children. JAMA, 306(14), 1566–1573.
18. Roth, C., Bjorke-Monsen, A. L., et al. (2013). Use of folic acid supplements in early pregnancy in relation to maternal plasma levels in week 18 of pregnancy. Molecular Nutrition & Food Research, 57(4), 653–660.
19. Rothenberg, S. P., da Costa, M. P., et al. (2004). Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. New England Journal of Medicine, 350(2), 134–142.
20. Schmidt, R. J. (2013). Maternal folic acid supplements associated with reduced autism risk in the child. Evidence-Based Medicine, 18, e53.
21. Schmidt, R. J., Hansen, R. L., et al. (2011). Prenatal vitamins, onecarbon metabolism gene variants, and risk for autism. Epidemiology, 22(4), 476–485.
22. Schmidt, R. J., Tancredi, D. J., et al. (2012). Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. American Journal of Clinical Nutrition, 96(1), 80–89.
23. Shiraishi, M., Haruna, M., et al. (2012). Validity and reproducibility of folate and vitamin B(12) intakes estimated from a selfadministered diet history questionnaire in Japanese pregnant women. Nutrition Journal, 11, 15.
24. Steenweg-de Graaff, J., Roza, S. J., et al. (2012). Maternal folate status in early pregnancy and child emotional and behavioral problems: The Generation R Study. American Journal of Clinical Nutrition, 95(6), 1413–1421.
25. Suren, P., Roth, C., et al. (2013). Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA, 309(6), 570–577.
26. Tamura, T., Goldenberg, R. L., et al. (2005). Folate status of mothers during pregnancy and mental and psychomotor development of their children at five years of age. Pediatrics, 116(3), 703–708.
27. Thomas, D. G., Grant, S. L., et al. (2009). The role of iron in neurocognitive development. Developmental Neuropsychology, 34(2), 196–222.
28. Zhang, T., Lou, J., et al. (2013). Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature. PLoS ONE, 8(4), e59570.