Development of hepatitis C virus genotype 3a cell culture system

Hepatology

Volumn 60, Issue 6, 2014, Pages 1838-1850

  Kim, Sulyi ^a   Date, Tomoko ^a   Yokokawa, Hiroshi ^a,b   Kono, Tamaki ^a   Aizaki, Hideki ^a   Maurel, Patrick ^c   Gondeau, Claire ^c,d   Wakita, Takaji ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b TORAY INDUSTRIES INC   (Japan)

^c INSERM   (France)

^d HÔPITAL SAINT ELOI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 2' FLUORO 2' METHYLCYTIDINE; ALPHA INTERFERON; ANTIVIRUS AGENT; CORE PROTEIN; CYCLOSPORIN A; DACLATASVIR; FAT DROPLET; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; TELAPREVIR;

ARTICLE; CELL CULTURE; FLUORESCENCE MICROSCOPY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS SUBTYPE 3A; HUMAN; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; CELL LINE; CULTURE TECHNIQUE; EVALUATION STUDY; HEPACIVIRUS; MICROBIAL SENSITIVITY TEST; MUTATION; PHYSIOLOGY; VIRION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CELL CULTURE TECHNIQUES; CELL LINE; GENOTYPE; HEPACIVIRUS; LIPID DROPLETS; MICROBIAL SENSITIVITY TESTS; MUTATION; VIRION; VIRUS REPLICATION;

EID: 84912016197     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27197     Document Type: Article

References (36)

1. Feld JJ, Liang TJ. Hepatitis C - identifying patients with progressive liver injury. Hepatology 2006;43:S194-206.
2. Smith DB, Bukh J, Kuiken C, Muerhoff AS, Rice CM, Stapleton JT, et al. Expanded classification of hepatitis C Virus into 7 genotypes and 67 subtypes: updated criteria and assignment web resource. Hepatology 2014;59:318-327.
3. Butt S, Idrees M, Akbar H, ur Rehman I, Awan Z, Afzal S, et al. The changing epidemiology pattern and frequency distribution of hepatitis C virus in Pakistan. Infect Genet Evol 2010;10:595-600.
4. Rehman IU, Idrees M, Ali M, Ali L, Butt S, Hussain A, et al. Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan. Genet Vaccines Ther 2011;9:2.
5. Hui JM, Kench J, Farrell GC, Lin R, Samarasinghe D, Liddle C, et al. Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection. J Gastroenterol Hepatol 2002;17:873-881.
6. Rubbia-Brandt L, Quadri R, Abid K, Giostra E, Male PJ, Mentha G, et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 2000;33:106-115.
7. Kumar D, Farrell GC, Fung C, George J. Hepatitis C virus genotype 3 is cytopathic to hepatocytes: reversal of hepatic steatosis after sustained therapeutic response. Hepatology 2002;36:1266-1272.
8. Gottwein JM, Scheel TK, Jensen TB, Ghanem L, Bukh J. Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses. Gastroenterology 2011;141:1067-1079.
9. Saeed M, Gondeau C, Hmwe S, Yokokawa H, Date T, Suzuki T, et al. Replication of hepatitis C virus genotype 3a in cultured cells. Gastroenterology 2013;144:56-58 e57.
10. Saeed M, Scheel TK, Gottwein JM, Marukian S, Dustin LB, Bukh J, et al. Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells. Antimicrob Agents Chemother 2012;56:5365-5373.
11. Jhaveri R, McHutchison J, Patel K, Qiang G, Diehl AM. Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. J Infect Dis 2008;197:283-291.
12. Jhaveri R, Qiang G, Diehl AM. Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation. J Infect Dis 2009;200:1781-1788.
13. Qiang G, Jhaveri R. Lipid droplet binding of hepatitis C virus core protein genotype 3. ISRN Gastroenterol 2012;2012:176728.
14. Lindenbach BD, Evans MJ, Syder AJ, Wolk B, Tellinghuisen TL, Liu CC, et al. Complete replication of hepatitis C virus in cell culture. Science 2005;309:623-626.
15. Pietschmann T, Kaul A, Koutsoudakis G, Shavinskaya A, Kallis S, Steinmann E, et al. Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras. Proc Natl Acad Sci U S A 2006;103:7408-7413.
16. Kato T, Date T, Murayama A, Morikawa K, Akazawa D, Wakita T. Cell culture and infection system for hepatitis C virus. Nat Protoc 2006;1:2334-2339.
17. Wakita T. Isolation of JFH-1 strain and development of an HCV infection system. Methods Mol Biol 2009;510:305-327.
18. Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005;11:791-796.
19. Saeed M, Suzuki R, Kondo M, Aizaki H, Kato T, Mizuochi T, et al. Evaluation of hepatitis C virus core antigen assays in detecting recombinant viral antigens of various genotypes. J Clin Microbiol 2009;47:4141-4143.
20. Takeuchi T, Katsume A, Tanaka T, Abe A, Inoue K, Tsukiyama-Kohara K, et al. Real-time detection system for quantification of hepatitis C virus genome. Gastroenterology 1999;116:636-642.
21. Date T, Miyamoto M, Kato T, Morikawa K, Murayama A, Akazawa D, et al. An infectious and selectable full-length replicon system with hepatitis C virus JFH-1 strain. Hepatol Res 2007;37:433-443.
22. Kato T, Date T, Miyamoto M, Furusaka A, Tokushige K, Mizokami M, et al. Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon. Gastroenterology 2003;125:1808-1817.
23. Date T, Kato T, Kato J, Takahashi H, Morikawa K, Akazawa D, et al. Novel cell culture-adapted genotype 2a hepatitis C virus infectious clone. J Virol 2012;86:10805-10820.
24. Zhong J, Gastaminza P, Cheng G, Kapadia S, Kato T, Burton DR, et al. Robust hepatitis C virus infection in vitro. Proc Natl Acad Sci U S A 2005;102:9294-9299.
25. Olmstead AD, Knecht W, Lazarov I, Dixit SB, Jean F. Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents. PLoS Pathog 2012;8:e1002468.
26. Kato T, Matsumura T, Heller T, Saito S, Sapp RK, Murthy K, et al. Production of infectious hepatitis C virus of various genotypes in cell cultures. J Virol 2007;81:4405-4411.
27. Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Zayas M, et al. The lipid droplet is an important organelle for hepatitis C virus production. Nat Cell Biol 2007;9:1089-1097.
28. Gastaminza P, Dryden KA, Boyd B, Wood MR, Law M, Yeager M, et al. Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture. J Virol 2010;84:10999-11009.
29. Zhong J, Gastaminza P, Chung J, Stamataki Z, Isogawa M, Cheng G, et al. Persistent hepatitis C virus infection in vitro: coevolution of virus and host. J Virol 2006;80:11082-11093.
30. Anderson N, Borlak J. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol Rev 2008;60:311-357.
31. Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, et al. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem 2003;278:34268-34276.
32. Videla LA, Rodrigo R, Orellana M, Fernandez V, Tapia G, Quinones L, et al. Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients. Clin Sci (Lond) 2004;106:261-268.
33. Ma S, Yang D, Li D, Tan Y, Tang B, Yang Y. Inhibition of uncoupling protein 2 with genipin exacerbates palmitate-induced hepatic steatosis. Lipids Health Dis 2012;11:154.
34. Perlemuter G, Sabile A, Letteron P, Vona G, Topilco A, Chretien Y, et al. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 2002;16:185-194.
35. Mirandola S, Realdon S, Iqbal J, Gerotto M, Dal Pero F, Bortoletto G, et al. Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis. Gastroenterology 2006;130:1661-1669.
36. Jackel-Cram C, Babiuk LA, Liu Q. Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core. J Hepatol 2007;46:999-1008.