메뉴 건너뛰기




Volumn 200, Issue 11, 2009, Pages 1781-1788

Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; FAT DROPLET; TRIACYLGLYCEROL;

EID: 72849151027     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/648094     Document Type: Article
Times cited : (16)

References (42)
  • 1
    • 72849108033 scopus 로고    scopus 로고
    • National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Atlanta: Centers for Disease Control and Prevention
    • National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Viral hepatitis C fact sheet. Atlanta: Centers for Disease Control and Prevention, 2007.
    • (2007) Viral hepatitis C fact sheet
  • 5
    • 22044447648 scopus 로고    scopus 로고
    • Steatosis and chronic hepatitis C virus infection: Mechanisms and significance
    • DOI 10.1016/j.cld.2005.05.007, PII S1089326105000395, Hepatitis C Virus
    • Patel K, Zekry A, McHutchison JG. Steatosis and chronic hepatitis C virus infection: mechanisms and significance. Clin Liver Dis 2005; 9: 399-410. (Pubitemid 40968203) (Pubitemid 40968203)
    • (2005) Clinics in Liver Disease , vol.9 , Issue.3 , pp. 399-410
    • Patel, K.1    Zekry, A.2    McHutchison, J.G.3
  • 8
    • 0037301686 scopus 로고    scopus 로고
    • Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies
    • DOI 10.1136/gut.52.2.288
    • Castera L, Hezode C, Roudot-Thoraval F, et al. Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies. Gut 2003; 52:288-292 (Pubitemid 36115074) (Pubitemid 36115074)
    • (2003) Gut , vol.52 , Issue.2 , pp. 288-292
    • Castera, L.1    Hezode, C.2    Roudot-Thoraval, F.3    Bastie, A.4    Zafrani, E.-S.5    Pawlotsky, J.-M.6    Dhumeaux, D.7
  • 9
    • 0036828802 scopus 로고    scopus 로고
    • Hepatitis C virus and liver steatosis: Is it the virus? Yes it is, but not always
    • DOI 10.1053/jhep.2002.37118
    • Negro F. Hepatitis C virus and liver steatosis: is it the virus? Yes it is, but not always. Hepatology 2002; 36:1050-1052 (Pubitemid 35253419) (Pubitemid 35253419)
    • (2002) Hepatology , vol.36 , pp. 1050-1052
    • Negro, F.1
  • 11
    • 0036892355 scopus 로고    scopus 로고
    • Steatosis accelerates fibrosis development over time in hepatitis C virus genotype 3 infected patients
    • DOI 10.1016/S0168-8278(02)00299-4, PII S0168827802002994
    • Westin J, Nordlinder H, Lagging M, Norkrans G, Wejstal R. Steatosis accelerates fibrosis development over time in hepatitis C virus genotype 3 infected patients. J Hepatol 2002; 37:837-842 (Pubitemid 35404224) (Pubitemid 35404224)
    • (2002) Journal of Hepatology , vol.37 , Issue.6 , pp. 837-842
    • Westin, J.1    Nordlinder, H.2    Lagging, M.3    Norkrans, G.4    Wejstal, R.5
  • 13
    • 0141757418 scopus 로고    scopus 로고
    • Worsening of steatosis and fibrosis progression in hepatitis C
    • DOI 10.1136/gut.52.10.1531
    • Castera L, Pawlotsky JM, Dhumeaux D. Worsening of steatosis and fibrosis progression in hepatitis C. Gut 2003; 52:1531. (Pubitemid 37176738)
    • (2003) Gut , vol.52 , Issue.10 , pp. 1531
    • Castera, L.1    Pawlotsky, J.-M.2    Dhumeaux, D.3
  • 16
    • 0034987263 scopus 로고    scopus 로고
    • Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
    • DOI 10.1053/jhep.2001.24432
    • Adinolfi LE, Gambardella M, Andreana A, Tripodi MF, Utili R, Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001; 33:1358-1364 (Pubitemid 32496971) (Pubitemid 32496971)
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1358-1364
    • Adinolfi, L.E.1    Gambardella, M.2    Andreana, A.3    Tripodi, M.-F.4    Utili, R.5    Ruggiero, G.6
  • 18
    • 67650421993 scopus 로고    scopus 로고
    • The impact of hepatic steatosis on the natural history of chronic hepatitis C infection
    • Cross TJ, Quaglia A, Hughes S, Joshi D, Harrison PM. The impact of hepatic steatosis on the natural history of chronic hepatitis C infection. J Viral Hepat 2009; 16:492-499
    • (2009) J Viral Hepat , vol.16 , pp. 492-499
    • Cross, T.J.1    Quaglia, A.2    Hughes, S.3    Joshi, D.4    Harrison, P.M.5
  • 19
    • 0033224562 scopus 로고    scopus 로고
    • The molecular biology of hepatitis C virus: Genotypes and quasispecies
    • Forns X, Bukh J. The molecular biology of hepatitis C virus: genotypes and quasispecies. Clin Liver Dis 1999; 3:693-716.
    • (1999) Clin Liver Dis , vol.3 , pp. 693-716
    • Forns, X.1    Bukh, J.2
  • 22
    • 18244365866 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
    • DOI 10.1096/fj.01-0396com
    • Perlemuter G, Sabile A, Letteron P, et al. Hepatitis C virus core proteininhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 2002; 16:185-194 (Pubitemid 34113012) (Pubitemid 34113012)
    • (2002) FASEB Journal , vol.16 , Issue.2 , pp. 185-194
    • Perlemuter, G.1    Sabile, A.2    Letteron, P.3    Vona, G.4    Topilco, A.5    Chretien, Y.6    Koike, K.7    Pessayre, D.8    Chapman, J.9    Barba, G.10    Brechot, C.11
  • 25
    • 37549005607 scopus 로고    scopus 로고
    • The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly
    • Shavinskaya A, Boulant S, Penin F, McLauchlan J, Bartenschlager R. The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly. J Biol Chem 2007; 282:37158-37169
    • (2007) J Biol Chem , vol.282 , pp. 37158-37169
    • Shavinskaya, A.1    Boulant, S.2    Penin, F.3    McLauchlan, J.4    Bartenschlager, R.5
  • 26
    • 39749098739 scopus 로고    scopus 로고
    • Cellular determinants of hepatitis c virus assembly, maturation, degradation, and secretion
    • DOI 10.1128/JVI.02053-07
    • Gastaminza P, Cheng G, Wieland S, Zhong J, Liao W, Chisari FV. Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion. J Virol 2008; 82:2120-2129 (Pubitemid 351293514) (Pubitemid 351293514)
    • (2008) Journal of Virology , vol.82 , Issue.5 , pp. 2120-2129
    • Gastaminza, P.1    Cheng, G.2    Wieland, S.3    Zhong, J.4    Liao, W.5    Chisari, F.V.6
  • 27
    • 34547592075 scopus 로고    scopus 로고
    • Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus
    • DOI 10.1099/vir.0.82898-0
    • Boulant S, Targett-Adams P, McLauchlan J. Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus. J Gen Virol 2007; 88:2204-2213 (Pubitemid 47194217) (Pubitemid 47194217)
    • (2007) Journal of General Virology , vol.88 , Issue.8 , pp. 2204-2213
    • Boulant, S.1    Targett-Adams, P.2    McLauchlan, J.3
  • 28
    • 39149138470 scopus 로고    scopus 로고
    • Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation
    • DOI 10.1086/524846
    • Jhaveri R, McHutchison J, Patel K, Qiang G, Diehl AM. Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. J Infect Dis 2008; 197:283-291 (Pubitemid 351263449) (Pubitemid 351263449)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.2 , pp. 283-291
    • Jhaveri, R.1    McHutchison, J.2    Patel, K.3    Qiang, G.4    Diehl, A.M.5
  • 32
    • 0030273064 scopus 로고    scopus 로고
    • Hepatitis C virus core protein: Carboxy-terminal boundaries of two processed species suggest cleavage by a signal peptide peptidase
    • DOI 10.1006/viro.1996.0510
    • Hussy P, Langen H, Mous J, Jacobsen H. Hepatitis C virus core protein: carboxy-terminal boundaries of two processed species suggest cleavage by a signal peptide peptidase. Virology 1996; 224:93-104. (Pubitemid 26358104) (Pubitemid 26358104)
    • (1996) Virology , vol.224 , Issue.1 , pp. 93-104
    • Hussy, P.1    Langen, H.2    Mous, J.3    Jacobsen, H.4
  • 33
    • 0035576260 scopus 로고    scopus 로고
    • Intramembrane proteolysis of signal peptides: An essential step in the generation of HLA-E epitopes
    • Lemberg MK, Bland FA, Weihofen A, Braud VM, Martoglio B. Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes. J Immunol 2001; 167:6441-6446 (Pubitemid 33081577)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6441-6446
    • Lemberg, M.K.1    Bland, F.A.2    Weihofen, A.3    Braud, V.M.4    Martoglio, B.5
  • 34
    • 0036683052 scopus 로고    scopus 로고
    • Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets
    • DOI 10.1093/emboj/cdf414
    • McLauchlan J, Lemberg MK, Hope G, Martoglio B. Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein t lipid droplets. EMBO J 2002; 21:3980-3988 (Pubitemid 34857431) (Pubitemid 34857431)
    • (2002) EMBO Journal , vol.21 , Issue.15 , pp. 3980-3988
    • McLauchlan, J.1    Lemberg, M.K.2    Hope, G.3    Martoglio, B.4
  • 36
    • 2642539953 scopus 로고    scopus 로고
    • Intramembrane proteolysis and endoplasmic reticulum retention of hepatitis C virus core protein
    • DOI 10.1128/JVI.78.12.6370-6380.2004
    • Okamoto K, Moriishi K, Miyamura T, Matsuura Y. Intramembrane proteolysis and endoplasmic reticulum retention of hepatitis C virus core protein. J Virol 2004; 78:6370-6380 (Pubitemid 38715935) (Pubitemid 38715935)
    • (2004) Journal of Virology , vol.78 , Issue.12 , pp. 6370-6380
    • Okamoto, K.1    Moriishi, K.2    Miyamura, T.3    Matsuura, Y.4
  • 37
    • 50149086906 scopus 로고    scopus 로고
    • Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation
    • Okamoto K, Mori Y, Komoda Y, et al. Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation. J Virol 2008; 82: 8349-8361
    • (2008) J Virol , vol.82 , pp. 8349-8361
    • Okamoto, K.1    Mori, Y.2    Komoda, Y.3
  • 38
    • 70349243589 scopus 로고    scopus 로고
    • Sequential processing of hepatitis C virus core protein by host cell signal peptidase and signal peptide peptidase: A reassessment
    • Pène V, Hernandez C, Vauloup-Fellous C, Garaud-Aunis J, Rosenberg AR. Sequential processing of hepatitis C virus core protein by host cell signal peptidase and signal peptide peptidase: a reassessment. J Viral Hepat 2009; 16:705-715
    • (2009) J Viral Hepat , vol.16 , pp. 705-715
    • Pène, V.1    Hernandez, C.2    Vauloup-Fellous, C.3    Garaud-Aunis, J.4    Rosenberg, A.R.5
  • 39
    • 47749084704 scopus 로고    scopus 로고
    • Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production
    • Targett-Adams P, Hope G, Boulant S, McLauchlan J. Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production. J Biol Chem 2008; 283:16850-16859
    • (2008) J Biol Chem , vol.283 , pp. 16850-16859
    • Targett-Adams, P.1    Hope, G.2    Boulant, S.3    McLauchlan, J.4
  • 40
    • 34548130208 scopus 로고    scopus 로고
    • The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model
    • DOI 10.1136/gut.2006.108647
    • Hourioux C, Patient R, Morin A, et al. The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model. Gut 2007; 56:1302-1308 (Pubitemid 47300434) (Pubitemid 47300434)
    • (2007) Gut , vol.56 , Issue.9 , pp. 1302-1308
    • Hourioux, C.1    Patient, R.2    Morin, A.3    Blanchard, E.4    Moreau, A.5    Trassard, S.6    Giraudeau, B.7    Roingeard, P.8
  • 41
    • 34247636649 scopus 로고    scopus 로고
    • Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: Genotype-3a core has a stronger effect than genotype-1b core
    • DOI 10.1016/j.jhep.2006.10.019, PII S0168827806006179
    • Jackel-Cram C, Babiuk LA, Liu Q. Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core. J Hepatol 2007; 46:999-1008. (Pubitemid 46669729) (Pubitemid 46669729)
    • (2007) Journal of Hepatology , vol.46 , Issue.6 , pp. 999-1008
    • Jackel-Cram, C.1    Babiuk, L.A.2    Liu, Q.3
  • 42
    • 34648827871 scopus 로고    scopus 로고
    • Alanine scanning of the hepatitis C virus core protein reveals numerous residues essential for production of infectious virus
    • DOI 10.1128/JVI.00793-07
    • Murray CL, Jones CT, Tassello J, Rice CM. Alanine scanning of the hepatitis C virus core protein reveals numerous residues essential for production of infectious virus. J Virol 2007; 81:10220-10231 (Pubitemid 47463297) (Pubitemid 47463297)
    • (2007) Journal of Virology , vol.81 , Issue.19 , pp. 10220-10231
    • Murray, C.L.1    Jones, C.T.2    Tassello, J.3    Rice, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.