Isolation of angiotensin I-converting enzyme inhibitor from pepsin hydrolysate of porcine hemoglobin

European Food Research and Technology

Volumn 239, Issue 6, 2014, Pages 933-940

  Deng, HuiLing ^a   Zheng, Jiong ^a   Zhang, Fusheng ^a   Wang, Yang ^a   Kan, Jianquan ^a  

^a SOUTHWEST UNIVERSITY   (China)

Author keywords

ACE inhibitory peptide; Amino acid sequence; Porcine hemoglobin; Purification

Indexed keywords

AMINO ACIDS; HEMOGLOBIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE; PEPTIDES; PURIFICATION;

ACE INHIBITORY PEPTIDES; ACE-INHIBITORY ACTIVITY; AMINO ACID SEQUENCE; ANGIOTENSIN I CONVERTING ENZYME INHIBITOR; GEL CHROMATOGRAPHY; MACROPOROUS RESIN; PEPSIN HYDROLYSATES; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ENZYMATIC HYDROLYSIS;

SUS;

EID: 84911987065     PISSN: 14382377     EISSN: 14382385     Source Type: Journal    
DOI: 10.1007/s00217-014-2290-0     Document Type: Article

References (31)

1. Lopez-Fandino R, Otte J, van Camp J (2006) Physiological, chemical and technological aspects of milk-protein-derived peptides with antihypertensive and ACE-inhibitory activity. Int Dairy J 16(11):1277–1293. doi:10.1016/j.idairyj.2006.06.004
2. Silva ACSE, Flynn JT (2012) The renin-angiotensin-aldosterone system in 2011: role in hypertension and chronic kidney disease. Pediatr Nephrol 27(10):1835–1845. doi:10.1007/s00467-011-2002-y
3. Murray BA, FitzGerald RJ (2007) Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr Pharm Design 13(8):773–791. doi:10.2174/138161207780363068
4. Atkinson AB, Robertson JI (1979) Captopril in the treatment of clinical hypertension and cardiac failure. Lancet 2(8147):836–839. doi:10.1016/S0140-6736(79)92186-X
5. FitzGerald RJ, Murray BA, Walsh DJ (2004) Hypotensive peptides from milk proteins. J Nutr 134(4):980s–988s
6. Liu LL, Liu LY, Lu BY, Xia DZ, Zhang Y (2012) Evaluation of antihypertensive and antihyperlipidemic effects of bamboo shoot angiotensin converting enzyme inhibitory peptide in vivo. J Agric Food Chem 60(45):11351–11358. doi:10.1021/Jf303471f
7. Ferreira SH, e Silva MR (1965) Potentiation of bradykinin and eledoisin by BPF (bradykinin potentiating factor) from Bothrops jararaca venom. Experientia 21(6):347–349
8. Hyun CK, Shin HK (2000) Utilization of bovine blood plasma proteins for the production of angiotensin I converting enzyme inhibitory peptides. Process Biochem 36:6
9. Zhao Q, Le Coeur C, Piot JM (1997) Analysis of peptides from bovine hemoglobin and tuna myoglobin enzymatic hydrolysate: use of HPLC with on-line second-order derivative spectroscopy for the characterization of biologically active peptides. Analytica Chimica Acta 352:20
10. Zhao Q, Garreau I, Sannier F, Piot JM (1997) Opioid peptides derived from hemoglobin: hemorphins. Biopolymers 43(2):75–98. doi:10.1002/(SICI)1097-0282(1997)43:2<75:AID-BIP2>3.0.CO;2-X
11. Wu T, Coeur-Tourneur C, Dhont G, Cassez A, Fertein E, He XD, Chen WD (2014) Simultaneous monitoring of temporal profiles of NO3, NO2 and O-3 by incoherent broadband cavity enhanced absorption spectroscopy for atmospheric applications. J Quant Spectrosc Ra 133:199–205. doi:10.1016/j.jqsrt.2013.08.002
12. Wu KC, Lin ZY, Chiang SH, Chang CY (2004) Antioxidant properties of porcine blood protein before and after enzymatic hydrolysis. J Biomass Ener Soc China 23:6
13. Miyaguchi Y, Sakai K, Yonekura M, Tsutsumi M (1989) Some properties of succinglated globin. Nippon Shokuhin Kogyo Gakkaishi 36:6
14. Chen C, Chi YJ, Zhao MY, Xu W (2012) Influence of degree of hydrolysis on functional properties, antioxidant and ACE inhibitory activities of egg white protein hydrolysate. Food Sci Biotechnol 21(1):27–34. doi:10.1007/s10068-012-0004-6
15. Cushman DW, Cheung HS (1971) Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem Pharmacol 20(7):1637–1648
16. Lee JK, Jeon JK, Byun HG (2011) Effect of angiotensin I converting enzyme inhibitory peptide purified from skate skin hydrolysate. Food Chem 125(2):495–499. doi:10.1016/j.foodchem.2010.09.039
17. Knecht R, Seemuller U, Liersch M, Fritz H, Braun DG, Chang JY (1983) Sequence determination of eglin C using combined microtechniques of amino acid analysis, peptide isolation, and automatic Edman degradation. Anal Biochem 130(1):65–71
18. Chang CY, Wu KC, Chiang SH (2007) Antioxidant properties and protein compositions of porcine haemoglobin hydrolysates. Food Chem 100(4):1537–1543. doi:10.1016/j.foodchem.2005.12.019
19. Vossenberg P, Beeftink HH, Nuijens T, Quaedflieg PJLM, Stuart MAC, Tramper J (2013) Dipeptide synthesis in near-anhydrous organic media: long-term stability and reusability of immobilized Alcalase. J Mol Catal B-Enzym 93:23–27. doi:10.1016/j.molcatb.2013.03.014
20. Zhao YH, Li BF, Liu ZY, Dong SY, Zhao X, Zeng MY (2007) Antihypertensive effect and purification of an ACE inhibitory peptide from sea cucumber gelatin hydrolysate. Process Biochem 42(12):1586–1591. doi:10.1016/j.procbio.2007.08.011
21. Zhong F, Liu JM, Ma JG, Shoemaker CF (2007) Preparation of hypocholesterol peptides from soy protein and their hypocholesterolemic effect in mice. Food Res Int 40(6):661–667. doi:10.1016/j.foodres.2006.11.011
22. Zhang FX, Wang Z, Xu SY (2009) Macroporous resin purification of grass carp fish (Ctenopharyngodon idella) scale peptides with in vitro angiotensin-I converting enzyme (ACE) inhibitory ability. Food Chem 117(3):387–392. doi:10.1016/j.foodchem.2009.04.015
23. Suetsuna K, Ukeda H, Ochi H (2000) Isolation and characterization of free radical scavenging activities peptides derived from casein. J Nutr Biochem 11(3):128–131. doi:10.1016/S0955-2863(99)00083-2
24. Suetsuna K, Yamagami M, Kuwata K (1988) Inhibitory activity against angiotensin I-converting enzyme of peptides originating from fish and shellfish muscle. Nippon Suisan Gakkaishi 54(10):5
25. Pihlanto-Leppala A, Koskinen P, Piilola K, Tupasela T, Korhonen H (2000) Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. J Dairy Res 67(1):53–64
26. Haque E, Chand R (2008) Antihypertensive and antimicrobial bioactive peptides from milk proteins. Eur Food Res Technol 227(1):7–15. doi:10.1007/s00217-007-0689-6
27. Chen QH, Xuan GD, Fu ML, He GQ, Wang W, Zhang HB, Ruan H (2007) Effect of angiotensin I-converting enzyme inhibitory peptide from rice dregs protein on antihypertensive activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr 16:281–285
28. Jia J, Zhou Y, Lu J, Chen A, Li Y, Zheng G (2010) Enzymatic hydrolysis of Alaska pollack (Theragra chalcogramma) skin and antioxidant activity of the resulting hydrolysate. J Sci Food Agric 90(4):635–640. doi:10.1002/jsfa.3861
29. Ruiz JAG, Ramos M, Recio I (2004) Angiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese. Stability under simulated gastrointestinal digestion. Int Dairy J 14(12):1075–1080. doi:10.1016/j.idairyj.2004.04.007
30. Saito T, Nakamura T, Kitazawa H, Kawai Y, Itoh T (2000) Isolation and structural analysis of antihypertensive peptides that exist naturally in Gouda cheese. J Dairy Sci 83(7):1434–1440. doi:10.3168/jds.S0022-0302(00)75013-2
31. Yu Y, Hu J, Miyaguchi Y, Bai X, Du Y, Lin B (2006) Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from porcine hemoglobin. Peptides 27(11):2950–2956. doi:10.1016/j.peptides.2006.05.025