Regioselective hydroxylation of 17β-estradiol by mutants of CYP102A1 from Bacillus megaterium

Biotechnology Letters

Volumn 36, Issue 12, 2014, Pages 2501-2506

  Cha, Gun Su ^a   Ryu, Sang Hoon ^a   Ahn, Taeho ^a   Yun, Chul Ho ^a  

^a Chonnam National University   (South Korea)

Author keywords

17 Estradiol; CYP102A1 mutant; Human metabolite; Hydroxylation; Regioselectivity

Indexed keywords

BACTERIOLOGY; BIOMOLECULES; METABOLITES; REGIOSELECTIVITY; STEROID HORMONES;

BACILLUS MEGATERIUM; CYP102A1 MUTANT; HUMAN CYTOCHROME; HUMAN METABOLITES; RANDOM MUTAGENESIS; REGIO-SELECTIVE;

HYDROXYLATION;

BACILLUS MEGATERIUM;

BACTERIAL PROTEIN; CYTOCHROME P450; ESTRADIOL; FLAVOCYTOCHROME P450 BM3 MONOXYGENASES; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

BACILLUS MEGATERIUM; BIOTRANSFORMATION; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HYDROXYLATION; METABOLISM; MUTAGENESIS;

BACILLUS MEGATERIUM; BACTERIAL PROTEINS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ESTRADIOL; HYDROXYLATION; MUTAGENESIS; MUTANT PROTEINS; NADPH-FERRIHEMOPROTEIN REDUCTASE; SUBSTRATE SPECIFICITY;

EID: 84911977066     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1628-9     Document Type: Article

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