GRP Receptor Imaging of Prostate Cancer Using [99mTc]Demobesin 4: a First-in-Man Study

Molecular Imaging and Biology

Volumn 16, Issue 6, 2014, Pages 888-895

  Mather, Stephen J ^a   Nock, Berthold A ^b   Maina, Theodosia ^b   Gibson, Vickie ^c   Ellison, David ^a   Murray, Iain ^c   Sobnack, Ravin ^c   Colebrook, Steve ^d   Wan, Susan ^d   Halberrt, Gavin ^e   Szysko, Teresa ^a,e   Powles, Thomas ^a   Avril, Norbert ^a,e  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

GRP receptor; Imaging; Peptide; Tc 99m

Indexed keywords

BOMBESIN RECEPTOR; DEMOBESIN 4 TC 99M; GASTRIN RELEASING PEPTIDE RECEPTOR; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; BOMBESIN; TECHNETIUM 99M DEMOBESIN 1; TECHNETIUM COMPLEX;

ADULT; AGED; ARTICLE; BONE SCINTISCANNING; CANCER SURGERY; CONSTIPATION; CONTROLLED STUDY; CT-SPECT SCANNER; DIARRHEA; DISTANT METASTASIS; DISTRIBUTION HALF-LIFE; DOSE RESPONSE; DOSIMETRY; DRUG CLEARANCE; DRUG EXCRETION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG TOLERABILITY; DRUG UPTAKE; DYSGEUSIA; ELIMINATION HALF-LIFE; FIRST IN HUMAN STUDY; FOLLOW UP; HUMAN; IMAGE ANALYSIS; IN VIVO STUDY; INJECTION SITE PAIN; KIDNEY CLEARANCE; LIVER METASTASIS; MIDDLE AGED; NAUSEA; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 1 CLINICAL TRIAL; PLASMA CLEARANCE; PROSTATE; PROSTATE CANCER; SINGLE DRUG DOSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; URINARY EXCRETION; VOMITING; WHOLE BODY IMAGING; ANALOGS AND DERIVATIVES; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; MALE; METABOLISM; PROSTATE TUMOR; SCINTISCANNING;

AGED; BOMBESIN; HUMANS; MALE; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; PROSTATIC NEOPLASMS; RADIOPHARMACEUTICALS; RECEPTORS, BOMBESIN; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 84911968420     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-014-0754-z     Document Type: Article

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