Association between the metabolic syndrome, its individual components, and unprovoked venous thromboembolism: Results of a patient-level meta-analysis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 11, 2014, Pages 2478-2485

  Ageno, Walter ^a   Di Minno, Matteo N D ^b,c   Ay, Cihan ^d   Jang, Moon Ju ^e   Hansen, John Bjarne ^f   Steffen, Lyn M ^g   Vayà, Amparo ⁱ   Rattazzi, Marcello ^j   Pabinger, Ingrid ^d   Oh, Doyeun ^e   Di Minno, Giovanni ^c   Braekkan, Sigrid K ^f   Cushman, Mary ^h   Bonet, Elena ⁱ   Pauletto, Paolo ^j   Squizzato, Alessandro ^a   Dentali, Francesco ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b CENTRO CARDIOLOGICO MONZINO   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e CHA University   (South Korea)

^f UNIVERSITY OF TROMSØ   (Norway)

^g UNIVERSITY OF MINNESOTA   (United States)

^h UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

ⁱ HOSPITAL UNIVERSITARIO LA FE   (Spain)

^j CA FONCELLO HOSPITAL   (Italy)

more..

Author keywords

Metabolic syndrome X; Obesity; Pulmonary embolism; Venous thromboembolism; Venous thrombosis

Indexed keywords

ABDOMINAL OBESITY; AGE; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CASE CONTROL STUDY; COHORT ANALYSIS; DEEP VEIN THROMBOSIS; DISEASE ASSOCIATION; HUMAN; LUNG EMBOLISM; METABOLIC SYNDROME X; OBESITY; PATHOGENESIS; PREDICTOR VARIABLE; RISK ASSESSMENT; VENOUS THROMBOEMBOLISM; ADULT; AGED; COMPLICATION; FEMALE; MALE; META ANALYSIS; MIDDLE AGED; RISK FACTOR; STATISTICAL MODEL;

ADULT; AGED; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HUMANS; LOGISTIC MODELS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY, ABDOMINAL; RISK FACTORS; VENOUS THROMBOEMBOLISM;

EID: 84911946400     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.304085     Document Type: Article

References (39)

1. Heit JA, O'Fallon WM, Petterson TM, Lohse CM, Silverstein MD, Mohr DN, Melton LJ III. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med. 2002;162:1245-1248.
2. White RH. The epidemiology of venous thromboembolism. Circulation. 2003;107(23 suppl 1):I4-I8.
3. Agnelli G, Verso M, Ageno W, Imberti D, Moia M, Palareti G, Rossi R, Pistelli R; MASTER Investigators. The MASTER registry on ven ous thromboembolism: description of the study cohort. Thromb Res. 2008;121:605-610.
4. Becattini C, Agnelli G, Prandoni P, Silingardi M, Salvi R, Taliani MR, Poggio R, Imberti D, Ageno W, Pogliani E, Porro F, Casazza F. A prospective study on cardiovascular events after acute pulmonary embolism. Eur Heart J. 2005;26:77-83.
5. Prandoni P, Ghirarduzzi A, Prins MH, Pengo V, Davidson BL, Sø rensen H, Pesavento R, Iotti M, Casiglia E, Iliceto S, Pagnan A, Lensing AW. Venous thromboembolism and the risk of subsequent symptomatic atherosclerosis. J Thromb Haemost. 2006;4:1891-1896.
6. Schulman S, Lindmarker P, Holmström M, Lärfars G, Carlsson A, Nicol P, Svensson E, Ljungberg B, Viering S, N ordlander S, Leijd B, Jahed K, Hjorth M, Linder O, Beckman M. Post-thrombotic syndrome, recurrence, and death 10 years after the first episode of venous thromboembolism treated with warfarin for 6 weeks or 6 months. J Thromb Haemost. 2006;4:734-742.
7. Bova C, Marchiori A, Noto A, Rossi V, Daniele F, Santoro C, Ricchio R, De Lorenzo R, Umbaca R, Prandoni P. Incidence of arterial cardiovascular event s in patients with idiopathic venous thromboembolism. A retrospective cohort study. Thromb Haemost. 2006;96:132-136.
8. Sø rensen HT, Horvath-Puho E, Pedersen L, Baron JA, Prandoni P. Venous thromb oembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet. 2007;370:1773-1779.
9. Becattini C, Vedovati MC, Ageno W, Dentali F, Agnelli G . Incidence of arterial cardiovascular events after venous thromboembolism: a systematic review and a meta-analysis. J Thromb Haemost. 2010;8:891-897.
10. Hansson PO, Eriksson H, Welin L, Svärdsudd K, Wilhelmsen L. Smoking and abdominal obesity: risk factors for venous thromboembolism among middle-aged men: "the study of men born in 1913 ". Arch Intern Med. 1999;159:1886-1890.
11. Samama MM. An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study. Arch Intern Med. 2000;160:3415-3420.
12. Ageno W, Becattini C, Brighton T, Selby R, Kamphuisen PW. Cardiovascular risk factors and venous thromboembolism: a meta-analysis. Circulation. 2008;117:93-102.
13. Expert Panel on Detection, Evaluation, and Treatment of Hig h Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2 001;285:2486-2496.
14. Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, Somers VK, Montori VM. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and me ta-analysis of longitudinal studies. J Am Coll Cardiol. 2007;49:403-414.
15. Ageno W, Prandoni P, Romualdi E, Ghirarduzzi A, Dentali F, Pesavento R, Crowther M, Venco A. The metab olic syndrome and the risk of venous thrombosis: a case-control study. J Thromb Haemost. 2006;4:1914-1918.
16. Ambrosetti M, Ageno W, Salerno M, Pedretti RF, Salerno-Uriarte JA. Metabolic syn drome as a risk factor for deep vein thrombosis after acute cardiac conditions. Thromb Res. 2007;120:815-818.
17. Ay C, Tengler T, Vormittag R, Simanek R, Dorda W, Vukovich T, Pabinger I. Venous thromboembolism-A manifestation of the metabolic syndrome. Haematologica. 2007;92:374-380.
18. Jang MJ, Choi WI, Bang SM, Lee T, Kim YK, Ageno W, Oh D. Metabolic syndrome is associated with venous thromboembolism in the Korean population. Arterioscler Thromb Vasc Biol. 2009;29:311-315.
19. Borch KH, Braekkan SK, Mathiesen EB, Njølstad I, Wilsgaard T, Stø rmer J, Hansen JB. Abdominal obesity is essential for the risk of venous thromboembolism in the metabolic syndrome: the Tromsø study. J Thromb Haemost. 2009;7:739-745.
20. Steffen LM, Cushman M, Peacock JM, Heckbert SR, Jacobs DR Jr, Rosamond WD, Folsom AR. Metabolic syndrome and risk of venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology. J Thromb Haemost. 2009;7:746-751.
21. Vayá A, Martínez-Triguero ML, España F, Todolí JA, Bonet E, Corella D. The metabolic syndrome and its individual components: its association with venous thromboembolism in a Mediterranean population. Metab Syndr Relat Disord. 2011;9:197-201.
22. Di Minno MN, Tufano A, Guida A, Di Capua M, De Gregorio AM, Cerbone AM, Tarantino G, Di Minno G. Abnormally high prevalence of major component s of the metabolic syndrome in subjects with early-onset idiopathic venous thromboembolism. Thromb Res. 2011;127:193-197.
23. Rattazzi M,Villalta S,Galliazzo S,Del Pup L,et al. Low CD34( +) cells, high neutrophils and the metabolic syndrome are associated with an increased risk of venous thromboembolism. Clin Sci (Lond). 2013;125:211-218.
24. Dentali F, Squizzato A, Ageno W. The metabolic syndrome as a risk factor for venous and arterial thrombosis. Semin Thromb Hemost. 2009;35:451-457.
25. Meltzer ME, Lisman T, de Groot PG, Meijers JC, le Cessie S, Doggen CJ, Rosend aal FR. Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1. Blood. 2010;116:113-121.
26. Meltzer ME, Bol L, Rosendaal FR, Lis man T, Cannegieter SC. Hypofibrinolysis as a risk factor for recurrent venous thrombosis; results of the LETS follow-up study. J Thromb Haemost. 2010;8:605-607.
27. Opie LH. Metabolic syndrome. Circulation. 2007;115:e32-e35.
28. Alberti KG, Zimmet P, Shaw J; IDF Epidemiology Task Force Consensus Group. The metabolic syndrome-A new worldwide definition. Lancet. 2005;366:1059-1062.
29. Dekker JM, Girman C, Rhodes T, Nijpels G, Stehouwer CD, Bouter LM, Heine RJ. Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study. Circulation. 2005;112:666-673.
30. Wilson PW, D'Agostino RB, Parise H, Sullivan L, Meigs JB. Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation. 2005;112:3066-3 072.
31. van Stralen KJ, Le Cessie S, Rosendaal FR, Doggen CJ. Regular sports activities decrease the risk of venous thrombosis. J Thromb Haemost. 2007;5:2186-2192.
32. Ste ffen LM, Folsom AR, Cushman M, Jacobs DR Jr, Rosamond WD. Greater fish, fruit, and vegetable intakes are related to lower incidence of venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology. Circulatio n. 2007;115:188-195.
33. Fitzgerald KC, Chiuve SE, Buring JE, Ridker PM, Glynn RJ. Comparison of associations of adherence to a Dietary Approaches to Stop Hypertension (DASH)-style diet with risks of cardiovascular disease and venous thromb oembolism. J Thromb Haemost. 2012;10:189-198.
34. Hansen-Krone IJ, Enga KF, Njølstad I, Hansen JB, Braekkan SK. Heart healthy diet and risk of myocardial infarction and venous thromboembolism. The Tromsø Study. Thromb Haemost. 2012;108:554-560.
35. Squizzato A, Galli M, Romualdi E, Dentali F, Kamphuisen PW, Guasti L, Venco A, Ageno W. Statins, fibrates, and venous thromb oembolism: a meta-analysis. Eur Heart J. 2010;31:1248-1256.
36. Alexander CM, Landsman PB, Grundy SM. The influence of age and body mass index on the metabolic syndrome and its components. Diabetes Obes Metab. 2008;10:246-250.
37. Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: prevalence and associated risk factor findings in the US pop ulation from the Third National Health and Nutrition Examination Survey, 1988- 1994. Arch Intern Med. 2003;163:427-436.
38. Steering Committee of the WHO Western Pacific Region, IASO & IOTF. The Asia-Pacific Perspective: Redefining Obesity and Its Treatment. Sydney: Health Communications; 2000.
39. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr; International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Ass o ciation for the Study of Obesity. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-1645.