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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 24, 2014, Pages 5782-5786

Design and synthesis of substituted morpholin/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential

(14) Bala, Veenu a,c Jangir, Santosh a Kumar, Vikas b Mandalapu, Dhanaraju a Gupta, Sonal a Kumar, Lalit a Kushwaha, Bhavana a Chhonker, Yashpal S a,c Krishna, Atul a Maikhuri, Jagdamba P a Shukla, Praveen K a Bhatta, Rabi S a,c Gupta, Gopal a Sharma, Vishnu L a,c

a CENTRAL DRUG RESEARCH INSTITUTE (India)

b National Institute of Pharmaceutical Education and Research (NIPER) (India)

c ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR (India)

Author keywords

Carbamodithioates; Microbicidal; Nonoxynol 9; Spermicide; Trichomonas vaginalis

Indexed keywords

ANTITRICHOMONAL AGENT; DITHIOCARBAMIC ACID; HEXOKINASE; METRONIDAZOLE; MICROBICIDE; MORPHOLINE DERIVATIVE; PIPERIDIN 1 YL CARBAMODITHIOATE DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; 2-(PYRROLIDIN-1-YL)ETHYL PIPERIDIN-1-YL-CARBAMODITHIOATE; ANTIFUNGAL AGENT; MORPHOLINE; PIPERIDINE; PIPERIDINE DERIVATIVE; SPERMICIDAL AGENT; THIOCARBAMIC ACID DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOCOMPATIBILITY; BIOLOGICAL ACTIVITY; CERVICAL CANCER CELL LINE; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SAFETY; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LACTOBACILLUS; MICROBIAL ACTIVITY; REACTION ANALYSIS; RISK ASSESSMENT; SPERM; SPERMATOZOON; STRUCTURE ACTIVITY RELATION; TRICHOMONAS VAGINALIS; VAGINA DISCHARGE; VAGINA FLORA; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; HELA CELL LINE; MALE; METABOLISM; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

TRICHOMONAS VAGINALIS;

ANTIFUNGAL AGENTS; CELL SURVIVAL; DRUG DESIGN; FEMALE; HELA CELLS; HEXOKINASE; HUMANS; LACTOBACILLUS; MALE; MICROBIAL SENSITIVITY TESTS; MORPHOLINES; PIPERIDINES; SPERMATOCIDAL AGENTS; SPERMATOZOA; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; THIOCARBAMATES; TRICHOMONAS VAGINALIS;

EID: 84911909652 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.10.040 Document Type: Article

Times cited : (14)

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