Free thiols in human spermatozoa: Are Na+/K+-ATPase, Ca2+-ATPase activities involved in sperm motility through peroxynitrite formation?

Reproductive BioMedicine Online

Volumn 18, Issue 1, 2009, Pages 132-140

  Vignini, Arianna ^a   Buldreghini, Eddi ^a   Nanetti, Laura ^a   Amoroso, Salvatore ^a   Boscaro, Marco ^b   Ricciardo Lamonica, Giuseppe ^a   Mazzanti, Laura ^a   Balercia, Giancarlo ^b  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b Azienda Ospedaliera Umberto I   (Italy)

Author keywords

Idiopathic asthenozoospermia; Membrane proteins; Oxidative stress; Peroxynitrite; Spermatozoa

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; PEROXYNITRITE; THIOL DERIVATIVE;

ADULT; ARTICLE; ASTHENOSPERMIA; CALCIUM CELL LEVEL; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OXIDATION; PATHOPHYSIOLOGY; SEMEN ANALYSIS; SPERMATOZOON MOTILITY; VELOCITY;

EID: 58649083039     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60435-X     Document Type: Article

References (49)

1. Agarwal A, Prabakaran SA 2005 Mechanism, measurement, and prevention of oxidative stress in male reproductive physiology. Indian Journal of Experimental Biology 43, 963-974.
2. Agarwal A, Gupta S, Sikka S 2006 The role of free radicals and antioxidants in reproduction. Current Opinion in Obstetrics and Gynecology 18, 325-332.
3. Agarwal A, Saleh RA, Bedaiwy MA 2003 Role of reactive oxygen species in the pathophysiology of human reproduction. Fertility and Sterility 79, 829-843
4. Aitken RJ 1994 A free radical theory of male infertility. Reproduction, Fertility and Development 6, 19-24.
5. Aitken RJ, Best FS, Richardson DW et al. 1982 An analysis of sperm function in cases of unexplained infertility: conventional criteria, movement characteristics, and fertilizing capacity. Fertility and Sterility 38, 212-221.
6. Baker MA, Aitken RJ 2005 Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility. Reproductive Biology and Endocrinology 3, 67.
7. Balercia G, Moretti S, Vignini A et al. 2004a Role of nitric oxide concentrations on human sperm motility. Journal of Andrology 25, 245-249.
8. Balercia G, Mosca F, Mantero F et al. 2004b Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertility and Sterility 81, 93-98.
9. Blanco G, Mercer RW 1998 Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function. American Journal of Physiology 275, F633-650.
10. Boni R, Gualtieri R, Talevi R et al. 2007 Calcium and other ion dynamics during gamete maturation and fertilization. Theriogenology 68, S156-164.
11. Bradford M 1976 A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Annals of Biochemistry 72, 248-254.
12. Buffone MG, Calamera JC, Verstraeten SV et al. 2005 Capacitation-associated protein tyrosine phosphorylation and membrane fluidity changes are impaired in the spermatozoa of asthenozoospermic patients. Reproduction 129, 697-705.
13. Bundy RE, Marczin N, Chester AH et al. 2000 A redox-based mechanism for nitric oxide-induced inhibition of DNA synthesis in human vascular smooth muscle cells. British Journal of Pharmacology 129, 1513-1521.
14. Cornwall GA, Vindivich D, Tillman S et al. 1988 The effect of sulfhydryl oxidation on the morphology of immature hamster epididymal spermatozoa induced to acquire motility in vitro. Biology of Reproduction 39, 141-155.
15. 2+-ATPase activity and on enzyme responsiveness in vitro to thyroid hormone and calmoduline. Diabetes 34, 639-646.
16. DeLamirande E, Jiang H, Zini A et al. 1997 Reactive oxygen species and sperm physiology. Reviews of Reproduction 2, 48-54.
17. Fiske CH, Subbarow Y 1925 The colorimetric determination of phosphorus. Journal of Biological Chemistry 66, 375-400.
18. Gil-Guzman E, Ollero M, Lopez MC et al. 2001 Differential production of reactive oxygen species by subsets of human spermatozoa at different stages of maturation. Human Reproduction 16, 1922-1930.
19. Grover AK, Khan I 1992 Calcium pump isoforms: diversity, selectivity and plasticity. Cell Calcium 13, 9-17.
20. 2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry 6, 3440-3450.
21. + ATPase by nitric oxide in mouse proximal tubule epithelial cells. Journal of Clinical Investigation 95, 2083-2088.
22. Iwasaki A, Gagnon C 1992 Formation of reactive oxygen species in spermatozoa of infertile patients. Fertility and Sterility 57, 409-416.
23. Jain S, Thomas M, Kumar GP et al. 1993 Programmed lipid peroxidation of biomembranes generating kinked phospholipids permitting local molecular mobility: a peroxidative theory of fluidity management. Biochemical and Biophysical Research Communications 195, 574-580.
24. Kao SH, Chao HT, Chen HW et al. 2008 Increase of oxidative stress in human sperm with lower motility. Fertility and Sterility 89, 1183-1190.
25. Kim YM, Son K, Hong ST et al. 1998 Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: nitric oxide induces phosphorylation of initiation factor eIF-2 alpha. Molecular Medicine 4, 179-190.
26. Kitao T, Hattori K 1983 Inhibition of erythrocyte ATPase activity by aclacinomycin and reverse effect of ascorbate on ATPase activity. Experientia 39, 1362-1364.
27. Koçak-Toker N, Aktan G, Aykaç-Toker G 2002 The role of Na,K-ATPase in human sperm motility. International Journal of Andrology 25, 180-185.
28. Kooy NW, Royall JA, Ischiropoulos H 1997 Oxidation of 2′,7′-dichlorofluorescin by peroxynitrite. Free Radical Research 27, 245-254.
29. Kosower NS, Katayose H, Yanagimachi R 1992 Thioldisulfide status and acridine orange fluorescence of mammalian sperm nuclei. Journal of Andrology 13, 342-348.
30. Lenzi A, Gandini L, Maresca V et al. 2000 Fatty acid composition of spermatozoa and immature germ cells. Molecular Human Reproduction 6, 226-231.
31. Luconi M, Baldi E 2003 How do sperm swim?: molecular mechanisms underlying sperm motility. Cellular and Molecular Biology 49, 357-369.
32. Mann T, Lutwak-Mann C 1981 Male Reproductive Function and Semen. Springer Verlag, Berlin 337 pp.
33. Marklund S, Marklund G 1974 Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. European Journal of Biochemistry 47, 469-474.
34. Mazzanti L, Rabini RA, Faloia E et al. 1990 Altered cellular calcium and sodium transport in diabetes mellitus. Diabetes 39, 850-854.
35. + ATPase activity. Nitric Oxide 4, 333-342.
36. +-ATPase inhibition by nitric oxide and peroxynitrite anion. Journal of Applied Toxicology 23, 275-278.
37. Nivsarkar M, Cherian B, Patel S 1998 A regulatory role of sulfhydryl groups in modulation of sperm membrane conformation by heavy metals: sulfhydryl groups as markers for infertility assessment. Biochemical and Biophysical Research Communications 247, 716-718.
38. Olson GE, Winfrey VP, Winer MA, Davenport GR 1987 Outer acrosomal membrane of guinea pig spermatozoa: isolation and structural characterization. Gamete Research 17, 77-94.
39. Oztezcan S, Turkoglu UM, Kervancioglu E et al. 1999 In vitro effects of peroxynitrite on human spermatozoa. Andrologia 31, 195-198.
40. Rao GHR 1988 Measurement of ionized calcium in normal human blood platelets. Annals of Biochemistry 169, 400-404.
41. Sanchez G, Nguyen AN, Timmerberg B et al. 2006 The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility. Molecular Human Reproduction 12: 565-576.
42. Sedlak J, Lindsay H 1968 Estimation of total, protein-bound and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Analytical Biochemistry 25, 192-205.
43. Shalgi R, Seligman J, Kosower NS 1989 Dynamics of the thiol status of rat spermatozoa during maturation: analysis with the fluorescent labelling agent monobromobimane. Biology of Reproduction 40, 1037-1045.
44. Shi YI, Ma XH 1998 Ion-channels reconstituted into lipid bilayer from human sperm plasma membrane. Molecular Reproduction and Development 50, 354-360.
45. Sinha S, Kumar GP, Laloraya M 1994 Abnormal physical architecture of the lipophilic domains of human sperm membrane in oligospermia: a logical cause for low fertility profiles. Biochemical and Biophysical Research Communications 198, 266-273.
46. Skou JC, Esmann M 1992 The Na,K-ATPase. Journal of Bioenergetics and Biomembranes 24, 249-261.
47. Takahashi A, Camacho P, Lechleiter JO et al. 1999 Measurement of intracellular calcium. Physiological Reviews 79, 1089-1125.
48. Vignini A, Nanetti L, Buldreghini E et al. 2006 The production of peroxynitrite by human spermatozoa may affect sperm motility through the formation of protein nitrotyrosine. Fertility and Sterility 85, 947-953.
49. World Health Organization 1999 WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. Cambridge University Press, Cambridge.