Streptococcus pneumoniae phosphoglycerate kinase is a novel complement inhibitor affecting the membrane attack complex formation

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32499-32511

  Blom, Anna M ^a   Bergmann, Simone ^b   Fulde, Marcus ^c   Riesbeck, Kristian ^a   Agarwal, Vaibhav ^a  

^a LUND UNIVERSITY   (Sweden)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BINDING SITES; ENZYMES;

BACTERIAL SURFACES; DOSE-DEPENDENT MANNER; GRAM-POSITIVE BACTERIUM; MEMBRANE ATTACK COMPLEXES; PHOSPHOGLYCERATE KINASE; SHEEP ERYTHROCYTES; STREPTOCOCCUS PNEUMONIAE; TISSUE PLASMINOGEN ACTIVATOR;

RECOMBINANT PROTEINS;

COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C7; COMPLEMENT COMPONENT C9; COMPLEMENT INHIBITOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; PHOSPHOGLYCERATE KINASE; PLASMIN; PLASMINOGEN; BACTERIAL PROTEIN; COMPLEMENT; PROTEIN BINDING; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEMENT DEPOSITION; COMPLEX FORMATION; DOSE RESPONSE; HEMOLYSIS; HUMAN; IONIC STRENGTH; NONHUMAN; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SHEEP; STREPTOCOCCUS PNEUMONIAE; ANIMAL; COMPLEMENT ACTIVATION; DRUG EFFECTS; ENZYMOLOGY; ERYTHROCYTE; FLOW CYTOMETRY; GENETICS; METABOLISM; POLYMERIZATION; SERUM;

STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BACTERIAL PROTEINS; COMPLEMENT ACTIVATION; COMPLEMENT C3B; COMPLEMENT C5; COMPLEMENT C7; COMPLEMENT C9; COMPLEMENT INACTIVATING AGENTS; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT SYSTEM PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FLOW CYTOMETRY; HEMOLYSIS; HUMANS; PHOSPHOGLYCERATE KINASE; PLASMINOGEN; POLYMERIZATION; PROTEIN BINDING; RECOMBINANT PROTEINS; SERUM; SHEEP; STREPTOCOCCUS PNEUMONIAE;

EID: 84911909640     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.610212     Document Type: Article

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