Trichinella spiralis paramyosin binds to c8 and c9 and protects the tissue-dwelling nematode from being attacked by host complement

PLoS Neglected Tropical Diseases

Volumn 5, Issue 7, 2011, Pages

  Zhang, Zhifei ^a   Yang, Jing ^a   Wei, Junfei ^a   Yang, Yaping ^a   Chen, Xiaoqin ^a   Zhao, Xi ^a   Gu, Yuan ^a   Cui, Shijuan ^a   Zhu, Xinping ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; MYOSIN ANTIBODY; PARAMYOSIN; RECOMBINANT PROTEIN; HELMINTH RNA; MESSENGER RNA; TROPOMYOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOLYSIS; DEVELOPMENTAL STAGE; ERYTHROCYTE COUNT; FEMALE; HOST PARASITE INTERACTION; HOST RESISTANCE; IMMUNE EVASION; IN VITRO STUDY; LARVAL STAGE; MICROFILARIA (NEMATODE LARVA); MOUSE; NONHUMAN; OUTER MEMBRANE; PARASITE IMMUNITY; PARASITE SURVIVAL; PARASITE VIABILITY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRICHINELLA SPIRALIS; ANIMAL; DNA SEQUENCE; DRUG ANTAGONISM; ERYTHROCYTE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENETICS; HEMOLYSIS; IMMUNOELECTRON MICROSCOPY; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOLECULAR GENETICS; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; COMPLEMENT C8; COMPLEMENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; ERYTHROCYTES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; HEMOLYSIS; IMMUNE EVASION; MICE; MICE, INBRED ICR; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, HELMINTH; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TRICHINELLA SPIRALIS; TROPOMYOSIN;

EID: 79960933692     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001225     Document Type: Article

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