-
1
-
-
75749108374
-
-
Chinese Patent Application No: CN 2007-10137548, 20070807; Chinese Patent
-
J. Chang, X. Bao, Q. Wang, X. Guo, W. Wang, X. Qi, Preparation of 2′-fluoro-4′-substituted nucleoside analogs as antiviral agents, Chinese Patent Application No: CN 2007-10137548, 20070807; Chinese Patent No: CN 101177442A, 20080514.
-
Preparation of 2′-fluoro-4′-substituted Nucleoside Analogs As Antiviral Agents
-
-
Chang, J.1
Bao, X.2
Wang, Q.3
Guo, X.4
Wang, W.5
Qi, X.6
-
3
-
-
79952576074
-
-
preparation methods and uses thereof. US Patent No: US 2010/0234584A1, 20100916
-
J. Chang, 2′-Fluorine-4′-substituted nucleoside analogues, preparation methods and uses thereof. US Patent No: US 2010/0234584A1, 20100916.
-
2′-Fluorine-4′-substituted Nucleoside Analogues
-
-
Chang, J.1
-
5
-
-
65649096631
-
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4′-azidocytidine against hepatitis C virus replication: The discovery of 4′-azido-2′-deoxy-2′-fluorocytidine and 4′-azido-2′-dideoxy-2′,2′-difluorocytidine
-
D.B. Smith, G. Kalayanov, C. Sund, A. Winqvist, T. Maltseva, and V.J. Leveque The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4′-azidocytidine against hepatitis C virus replication: the discovery of 4′-azido-2′-deoxy-2′-fluorocytidine and 4′-azido-2′-dideoxy-2′,2′-difluorocytidine J. Med. Chem. 52 2009 2971 2978
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2971-2978
-
-
Smith, D.B.1
Kalayanov, G.2
Sund, C.3
Winqvist, A.4
Maltseva, T.5
Leveque, V.J.6
-
7
-
-
79952574371
-
-
Q. Wang, X.B. Liu, Q.D. Wang, Y. Zhang, J.H. Jiang, X.H. Guo, Q.X. Fan, L.Y. Zheng, X.J. Yu, N. Wang, Z.L. Pan, C.J. Song, W.Q. Qi, and J.B. Chang Biochem. Pharmacol. 81 2011 848 855
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 848-855
-
-
Wang, Q.1
Liu, X.B.2
Wang, Q.D.3
Zhang, Y.4
Jiang, J.H.5
Guo, X.H.6
Fan, Q.X.7
Zheng, L.Y.8
Yu, X.J.9
Wang, N.10
Pan, Z.L.11
Song, C.J.12
Qi, W.Q.13
Chang, J.B.14
-
9
-
-
84861674959
-
-
L.Y. Zheng, Q. Wang, X.R. Yang, X.H. Guo, L. Chen, L. Tao, L.H. Dong, Y.J. Li, H.Y. An, X.J. Yu, Q.D. Wang, and J.B. Chang Antivir. Ther. 17 2012 679 687
-
(2012)
Antivir. Ther.
, vol.17
, pp. 679-687
-
-
Zheng, L.Y.1
Wang, Q.2
Yang, X.R.3
Guo, X.H.4
Chen, L.5
Tao, L.6
Dong, L.H.7
Li, Y.J.8
An, H.Y.9
Yu, X.J.10
Wang, Q.D.11
Chang, J.B.12
-
10
-
-
84871915422
-
-
Y.B. Zhou, Y. Zhang, X.A. Yang, J. Zhao, L.Y. Zheng, C.Y. Sun, J.H. Jiang, Q.H. Yang, Q.D. Wang, and J.B. Chang Antivir. Ther. 17 2012 1593 1599
-
(2012)
Antivir. Ther.
, vol.17
, pp. 1593-1599
-
-
Zhou, Y.B.1
Zhang, Y.2
Yang, X.A.3
Zhao, J.4
Zheng, L.Y.5
Sun, C.Y.6
Jiang, J.H.7
Yang, Q.H.8
Wang, Q.D.9
Chang, J.B.10
-
11
-
-
80052925838
-
-
Q. Wang, W.D. Hu, S.Y. Wang, Z.L. Pan, L. Tao, X.H. Guo, K.D. Qian, C.H. Chen, K.H. Lee, and J.B. Chang Eur. J. Med. Chem. 46 2011 4178 4183
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 4178-4183
-
-
Wang, Q.1
Hu, W.D.2
Wang, S.Y.3
Pan, Z.L.4
Tao, L.5
Guo, X.H.6
Qian, K.D.7
Chen, C.H.8
Lee, K.H.9
Chang, J.B.10
-
12
-
-
77953873094
-
-
Q. Wang, Y.F. Li, C.J. Song, K.D. Qian, C.H. Chen, K.H. Lee, and J.B. Chang Bioorg. Med. Chem. Lett. 20 2010 4053 4056
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 4053-4056
-
-
Wang, Q.1
Li, Y.F.2
Song, C.J.3
Qian, K.D.4
Chen, C.H.5
Lee, K.H.6
Chang, J.B.7
-
14
-
-
36949066642
-
-
M.F. Perutz, M.G. Rossmann, A.F. Cullis, H. Muirhead, G. Will, and A.C.T. North Nature 185 1960 416 422
-
(1960)
Nature
, vol.185
, pp. 416-422
-
-
Perutz, M.F.1
Rossmann, M.G.2
Cullis, A.F.3
Muirhead, H.4
Will, G.5
North, A.C.T.6
-
20
-
-
70349932423
-
-
G.M. Morris, R. Huey, W. Lindstrom, M.F. Sanner, R.K. Belew, D.S. Goodsell, and A.J. Olson J. Comput. Chem. 16 2009 2785 2791
-
(2009)
J. Comput. Chem.
, vol.16
, pp. 2785-2791
-
-
Morris, G.M.1
Huey, R.2
Lindstrom, W.3
Sanner, M.F.4
Belew, R.K.5
Goodsell, D.S.6
Olson, A.J.7
-
21
-
-
79959190033
-
-
Gaussian, Inc. Wallingford, CT
-
M.J. Frisch, G.W. Trucks, H.B. Schlegel, and G.E. Scuseria GAUSSIAN 09, Revision C.01 2010 Gaussian, Inc. Wallingford, CT
-
(2010)
GAUSSIAN 09, Revision C.01
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Scuseria, G.E.4
-
25
-
-
34547903944
-
-
S. Patil, A. Sandberg, E. Heckert, W. Self, and S. Seal Biomaterials 28 2007 4600 4607
-
(2007)
Biomaterials
, vol.28
, pp. 4600-4607
-
-
Patil, S.1
Sandberg, A.2
Heckert, E.3
Self, W.4
Seal, S.5
-
35
-
-
0037205125
-
-
M. Ranjan, P. Diffley, G. Stephen, D. Price, T.J. Walton, and R.P. Newton Life Sci. 71 2002 115 126
-
(2002)
Life Sci.
, vol.71
, pp. 115-126
-
-
Ranjan, M.1
Diffley, P.2
Stephen, G.3
Price, D.4
Walton, T.J.5
Newton, R.P.6
-
38
-
-
84865422449
-
-
R.Y. Wang, Y.H. Chai, R.Q. Wang, L. Zhang, J. Wu, and J.B. Chang Spectrochim. Acta A 96 2012 324 331
-
(2012)
Spectrochim. Acta A
, vol.96
, pp. 324-331
-
-
Wang, R.Y.1
Chai, Y.H.2
Wang, R.Q.3
Zhang, L.4
Wu, J.5
Chang, J.B.6
-
40
-
-
0033567380
-
-
A. Haouz, S.E. Mohsni, C. Zentz, F. Merola, and B. Alpert Eur. J. Biochem. 264 1999 250 257
-
(1999)
Eur. J. Biochem.
, vol.264
, pp. 250-257
-
-
Haouz, A.1
Mohsni, S.E.2
Zentz, C.3
Merola, F.4
Alpert, B.5
-
46
-
-
33644935077
-
-
G.L. Lin, Y.Y. Liao, X.H. Wang, S.L. Sheng, and D.Z. Yin Exp. Gerontol. 41 2006 328 336
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 328-336
-
-
Lin, G.L.1
Liao, Y.Y.2
Wang, X.H.3
Sheng, S.L.4
Yin, D.Z.5
|