메뉴 건너뛰기




Volumn 87, Issue 1044, 2014, Pages

Imageguided radiotherapy of the prostate using daily CBCT: The feasibility and likely benefit of implementing a margin reduction

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL ARTICLE; CONE BEAM COMPUTED TOMOGRAPHY; CONTROLLED STUDY; DOSE VOLUME HISTOGRAM; FEASIBILITY STUDY; HISTOGRAM; HUMAN; IMAGE GUIDED RADIOTHERAPY; MALE; PROSTATE CANCER; RADIATION DOSE DISTRIBUTION; RADIATION DOSE REDUCTION; TREATMENT OUTCOME; COMPUTER ASSISTED RADIOTHERAPY; PROCEDURES; PROSTATE; PROSTATIC NEOPLASMS; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL;

EID: 84911893986     PISSN: 00071285     EISSN: 1748880X     Source Type: Journal    
DOI: 10.1259/bjr.20140459     Document Type: Article
Times cited : (57)

References (47)
  • 1
    • 84911913892 scopus 로고    scopus 로고
    • London, UK: National Statistics
    • Office for National Statistics Mortality Statistics. Deaths registrered in 2010, England and Wales. London, UK: National Statistics; 2011.
    • (2011) Deaths Registrered in 2010, England and Wales
  • 2
    • 76049095874 scopus 로고    scopus 로고
    • Dose-volume constraints to reduce rectal side effects from prostate radiotherapy: Evidence from MRC RT01 Trial ISRCTN 47772397
    • Gulliford SL, Foo K, Morgan RC, Aird EG, Bidmead AM, Critchley H, et al. Dose-volume constraints to reduce rectal side effects from prostate radiotherapy: evidence from MRC RT01 Trial ISRCTN 47772397. Int J Radiat Oncol Biol Phys 2010; 76: 747-54. doi: 10.1016/j.ijrobp.2009.02.025
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 747-754
    • Gulliford, S.L.1    Foo, K.2    Morgan, R.C.3    Aird, E.G.4    Bidmead, A.M.5    Critchley, H.6
  • 3
    • 33746216870 scopus 로고    scopus 로고
    • Late rectal symptoms and quality of life after conformal radiation therapy for prostate cancer
    • Geinitz H, Zimmermann FB, Thamm R, Erber C, Müller T, Keller M, et al. Late rectal symptoms and quality of life after conformal radiation therapy for prostate cancer. Radio-ther Oncol 2006; 79: 341-7.
    • (2006) Radio-ther Oncol , vol.79 , pp. 341-347
    • Geinitz, H.1    Zimmermann, F.B.2    Thamm, R.3    Erber, C.4    Müller, T.5    Keller, M.6
  • 4
    • 4444270625 scopus 로고    scopus 로고
    • Measurements of intrafraction motion and interfrac-tion and intrafraction rotation of prostate by three-dimensional analysis of daily portal imaging with radiopaque markers
    • Aubry JF, Beaulieu L, Girouard LM, Aubin S, Tremblay D, Laverdière J, et al. Measurements of intrafraction motion and interfrac-tion and intrafraction rotation of prostate by three-dimensional analysis of daily portal imaging with radiopaque markers. Int J Radiat Oncol Biol Phys 2004; 60: 30-9.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 30-39
    • Aubry, J.F.1    Beaulieu, L.2    Girouard, L.M.3    Aubin, S.4    Tremblay, D.5    Laverdière, J.6
  • 5
    • 34249650238 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy using implanted fiducial markers with daily portal imaging: Assessment of prostate organ motion
    • Chen J, Lee RJ, Handrahan D, Sause WT. Intensity-modulated radiotherapy using implanted fiducial markers with daily portal imaging: assessment of prostate organ motion. Int J Radiat Oncol Biol Phys 2007; 68: 912-19.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 912-919
    • Chen, J.1    Lee, R.J.2    Handrahan, D.3    Sause, W.T.4
  • 9
    • 25844451193 scopus 로고    scopus 로고
    • Prostate position relative to pelvic bony anatomy based on intraprostatic gold markers and electronic portal imaging
    • Schallenkamp JM, Herman MG, Kruse JJ, Pisansky TM. Prostate position relative to pelvic bony anatomy based on intraprostatic gold markers and electronic portal imaging. Int J Radiat Oncol Biol Phys 2005; 63: 800-11.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 800-811
    • Schallenkamp, J.M.1    Herman, M.G.2    Kruse, J.J.3    Pisansky, T.M.4
  • 10
    • 0033974376 scopus 로고    scopus 로고
    • Short-course intensity-modulated radiotherapy for localized prostate cancer with daily transabdominal ultrasound localization of the prostate gland
    • Mohan DS, Kupelian PA, Willoughby TR. Short-course intensity-modulated radiotherapy for localized prostate cancer with daily transabdominal ultrasound localization of the prostate gland. Int J Radiat Oncol Biol Phys 2000; 46: 575-80.
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 575-580
    • Mohan, D.S.1    Kupelian, P.A.2    Willoughby, T.R.3
  • 11
    • 77951720308 scopus 로고    scopus 로고
    • Practical aspects of implementation of helical tomotherapy for intensity-modulated and image-guided radiotherapy
    • Burnet NG, Adams EJ, Fairfoul J, Tudor GS, Hoole AC, Routsis DS, et al. Practical aspects of implementation of helical tomotherapy for intensity-modulated and image-guided radiotherapy. Clin Oncol (R Coll Radiol) 2010; 22: 294-312. doi: 10.1016/j.clon.2010.02.003
    • (2010) Clin Oncol (R Coll Radiol) , vol.22 , pp. 294-312
    • Burnet, N.G.1    Adams, E.J.2    Fairfoul, J.3    Tudor, G.S.4    Hoole, A.C.5    Routsis, D.S.6
  • 12
    • 79954420210 scopus 로고    scopus 로고
    • Image-guided radiotherapy (IGRT) for prostate cancer comparing kV imaging of fiducial markers with cone beam computed tomography (CBCT)
    • Barney BM, Lee RJ, Handrahan D, Welsh KT, Cook JT, Sause WT. Image-guided radiotherapy (IGRT) for prostate cancer comparing kV imaging of fiducial markers with cone beam computed tomography (CBCT). Int J Radiat Oncol Biol Phys 2011; 80: 301-5. doi: 10.1016/j.ijrobp.2010.06.007
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 301-305
    • Barney, B.M.1    Lee, R.J.2    Handrahan, D.3    Welsh, K.T.4    Cook, J.T.5    Sause, W.T.6
  • 14
    • 33846829584 scopus 로고    scopus 로고
    • Comparison of localization performance with implanted fiducial markers and cone-beam computed tomography for on-line image-guided radiotherapy of the prostate
    • Moseley DJ, White EA, Wiltshire KL, Rosewall T, Sharpe MB, Siewerdsen JH, et al. Comparison of localization performance with implanted fiducial markers and cone-beam computed tomography for on-line image-guided radiotherapy of the prostate. Int J Radiat Oncol Biol Phys 2007; 67: 942-53.
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 942-953
    • Moseley, D.J.1    White, E.A.2    Wiltshire, K.L.3    Rosewall, T.4    Sharpe, M.B.5    Siewerdsen, J.H.6
  • 15
    • 84866089003 scopus 로고    scopus 로고
    • Consideration of the likely benefit from implementation of prostate image-guided radiotherapy using current margin sizes: A radiobiological analysis
    • Tudor GS, Rimmer YL, Nguyen TB, Cowen MA, Thomas SJ. Consideration of the likely benefit from implementation of prostate image-guided radiotherapy using current margin sizes: a radiobiological analysis. Br J Radiol 2012; 85: 1263-71. doi: 10.1259/bjr/27924223
    • (2012) Br J Radiol , vol.85 , pp. 1263-1271
    • Tudor, G.S.1    Rimmer, Y.L.2    Nguyen, T.B.3    Cowen, M.A.4    Thomas, S.J.5
  • 16
    • 38149102436 scopus 로고    scopus 로고
    • Question of dose, fractionation and technique: Ingredients for testing hypofractionation in prostate cancer-The CHHiP trial
    • Khoo VS, Dearnaley DP. Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer-the CHHiP trial. Clin Oncol (R Coll Radiol) 2008; 20: 12-14.
    • (2008) Clin Oncol (R Coll Radiol) , vol.20 , pp. 12-14
    • Khoo, V.S.1    Dearnaley, D.P.2
  • 17
    • 0034036868 scopus 로고    scopus 로고
    • BIOPLAN: Software for the biological evaluation of radiotherapy treatment plans
    • Sanchez-Nieto B, Nahum AE. BIOPLAN: software for the biological evaluation of radiotherapy treatment plans. Med Dosim 2000; 25: 71-6.
    • (2000) Med Dosim , vol.25 , pp. 71-76
    • Sanchez-Nieto, B.1    Nahum, A.E.2
  • 19
    • 0022323855 scopus 로고
    • Complication probability as assessed from dose-volume histograms
    • Lyman JT. Complication probability as assessed from dose-volume histograms. Radiat Res 1985; 104: S13-19.
    • (1985) Radiat Res , vol.104 , pp. S13-19
    • Lyman, J.T.1
  • 20
    • 0024317128 scopus 로고
    • Calculation of complication probability factors for non uniform normal tissue irradiation: The effective volume method
    • Kutcher GJ, Burman C. Calculation of complication probability factors for non uniform normal tissue irradiation: the effective volume method. Int J Radiat Oncol Biol Phys 1988; 16: 1623-30.
    • (1988) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1623-1630
    • Kutcher, G.J.1    Burman, C.2
  • 22
    • 76049102148 scopus 로고    scopus 로고
    • Reduction of dose delivered to organs at risk in prostate cancer patients via image-guided radiation therapy
    • Pawlowski JM, Yang ES, Malcolm AW, Coffey CW, Ding GX. Reduction of dose delivered to organs at risk in prostate cancer patients via image-guided radiation therapy. Int J Radiat Oncol Biol Phys 2010; 76: 924-34. doi: 10.1016/j.ijrobp.2009.06.068
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 924-934
    • Pawlowski, J.M.1    Yang, E.S.2    Malcolm, A.W.3    Coffey, C.W.4    Ding, G.X.5
  • 23
    • 79951849484 scopus 로고    scopus 로고
    • Does the planning dose-volume histogram represent treatment doses in image-guided prostate radiation therapy? Assessment with cone-beam computerised tomography scans
    • Hatton JA, Greer PB, Tang C, Wright P, Capp A, Gupta S, et al. Does the planning dose-volume histogram represent treatment doses in image-guided prostate radiation therapy? Assessment with cone-beam computerised tomography scans. Radiother Oncol 2011; 98: 162-8. doi: 10.1016/j.radonc.2011.01.006
    • (2011) Radiother Oncol , vol.98 , pp. 162-168
    • Hatton, J.A.1    Greer, P.B.2    Tang, C.3    Wright, P.4    Capp, A.5    Gupta, S.6
  • 25
    • 61649103524 scopus 로고    scopus 로고
    • Rectal motion can reduce CTV coverage and increase rectal dose during prostate radiotherapy: A daily cone-beam CT study
    • Sripadam R, Stratford J, Henry AM, Jackson A, Moore CJ, Price P. Rectal motion can reduce CTV coverage and increase rectal dose during prostate radiotherapy: a daily cone-beam CT study. Radiother Oncol 2009; 90: 312-17. doi: 10.1016/j.radonc.2008.07.031
    • (2009) Radiother Oncol , vol.90 , pp. 312-317
    • Sripadam, R.1    Stratford, J.2    Henry, A.M.3    Jackson, A.4    Moore, C.J.5    Price, P.6
  • 26
    • 0028865996 scopus 로고
    • Variation in volumes, dose-volume histograms, and estimated normal tissue complication probabilities of rectum and bladder during conformal radiotherapy of T3 prostate cancer
    • Lebesque JV, Bruce AM, Kroes AP, Touw A, Shouman RT, van Herk M. Variation in volumes, dose-volume histograms, and estimated normal tissue complication probabilities of rectum and bladder during conformal radiotherapy of T3 prostate cancer. Int J Radiat Oncol Biol Phys 1995; 33: 1109-19.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , pp. 1109-1119
    • Lebesque, J.V.1    Bruce, A.M.2    Kroes, A.P.3    Touw, A.4    Shouman, R.T.5    Van Herk, M.6
  • 27
    • 61749089077 scopus 로고    scopus 로고
    • Assessment of rectal distension in radiotherapy of prostate cancer using daily megavolt-age CT image guidance
    • Engels B, Tournel K, Soete G, Storme G. Assessment of rectal distension in radiotherapy of prostate cancer using daily megavolt-age CT image guidance. Radiother Oncol 2009; 90: 377-81. doi: 10.1016/j. radonc.2008.12.005
    • (2009) Radiother Oncol , vol.90 , pp. 377-381
    • Engels, B.1    Tournel, K.2    Soete, G.3    Storme, G.4
  • 28
    • 79951853867 scopus 로고    scopus 로고
    • A significant decrease in rectal volume and diameter during prostate IMRT
    • Anderson NS, Yu JB, Peschel RE, Decker RH. A significant decrease in rectal volume and diameter during prostate IMRT. Radiother Oncol 2011; 98: 197-91. doi: 10.1016/j. radonc.2010.12.005
    • (2011) Radiother Oncol , vol.98 , pp. 197-291
    • Anderson, N.S.1    Yu, J.B.2    Peschel, R.E.3    Decker, R.H.4
  • 29
    • 33748878207 scopus 로고    scopus 로고
    • Emptying the rectum before treatment delivery limits the variations of rectal dose-volume parameters during 3DCRT of prostate cancer
    • Stasi M, Munoz F, Fiorino C, Pasquino M, Baiotto B, Marini P, et al. Emptying the rectum before treatment delivery limits the variations of rectal dose-volume parameters during 3DCRT of prostate cancer. Radiother Oncol 2006; 80: 363-70.
    • (2006) Radiother Oncol , vol.80 , pp. 363-370
    • Stasi, M.1    Munoz, F.2    Fiorino, C.3    Pasquino, M.4    Baiotto, B.5    Marini, P.6
  • 30
    • 41749105794 scopus 로고    scopus 로고
    • Examining margin reduction and its impact on dose distribution for prostate cancer patients undergoing daily cone-beam computed tomography
    • Hammoud R, Patel SH, Pradhan D, Kim J, Guan H, Li S, et al. Examining margin reduction and its impact on dose distribution for prostate cancer patients undergoing daily cone-beam computed tomography. Int J Radiat Oncol Biol Phys 2008; 71: 265-73. doi: 10.1016/j.ijrobp.2008.01.015
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 265-273
    • Hammoud, R.1    Patel, S.H.2    Pradhan, D.3    Kim, J.4    Guan, H.5    Li, S.6
  • 31
    • 84860490575 scopus 로고    scopus 로고
    • Clinical impact of margin reduction on late toxicity and short-term biochemical control for patients treated with daily on-line image guided IMRT for prostate cancer
    • Crehange G, Mirjolet C, Gauthier M, Martin E, Truc G, Peignaux-Casasnovas K, et al. Clinical impact of margin reduction on late toxicity and short-term biochemical control for patients treated with daily on-line image guided IMRT for prostate cancer. Radiother Oncol 2012; 103: 244-6. doi: 10.1016/j. radonc.2011.10.025
    • (2012) Radiother Oncol , vol.103 , pp. 244-246
    • Crehange, G.1    Mirjolet, C.2    Gauthier, M.3    Martin, E.4    Truc, G.5    Peignaux-Casasnovas, K.6
  • 32
    • 58149147173 scopus 로고    scopus 로고
    • Inter-observer variability of prostate delineation on cone beam computerised tomography images
    • White EA, Brock KK, Jaffray DA, Catton CN. Inter-observer variability of prostate delineation on cone beam computerised tomography images. Clin Oncol (R Coll Radiol) 2009; 21: 32-8. doi: 10.1016/j. clon.2008.11.007
    • (2009) Clin Oncol (R Coll Radiol) , vol.21 , pp. 32-38
    • White, E.A.1    Brock, K.K.2    Jaffray, D.A.3    Catton, C.N.4
  • 33
    • 79951855794 scopus 로고    scopus 로고
    • Feasibility of CBCT-based target and normal structure delineation in prostate cancer radiotherapy: Multi-observer and image multi-modality study
    • Lütgendorf-Caucig C, Fotina I, Stock M, Pötter R, Goldner G, Georg D. Feasibility of CBCT-based target and normal structure delineation in prostate cancer radiotherapy: multi-observer and image multi-modality study. Radiother Oncol 2011; 98: 154-61. doi: 10.1016/j.radonc.2010.11.016
    • (2011) Radiother Oncol , vol.98 , pp. 154-161
    • Lütgendorf-Caucig, C.1    Fotina, I.2    Stock, M.3    Pötter, R.4    Goldner, G.5    Georg, D.6
  • 34
    • 34548474887 scopus 로고    scopus 로고
    • Intrafraction motion of the prostate during external-beam radiation therapy: Analysis of 427 patients with implanted fiducial markers
    • Kotte AN, Hofman P, Lagendijk JJ, van Vulpen M, van der Heide UA. Intrafraction motion of the prostate during external-beam radiation therapy: analysis of 427 patients with implanted fiducial markers. Int J Radiat Oncol Biol Phys 2007; 69: 419-25.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 419-425
    • Kotte, A.N.1    Hofman, P.2    Lagendijk, J.J.3    Van Vulpen, M.4    Van Der Heide, U.A.5
  • 37
    • 84873324971 scopus 로고    scopus 로고
    • Relationship of imaging frequency and planning margin to account for intrafraction prostate motion: Analysis based on real-time monitoring data
    • Curtis W, Khan M, Magnelli A, Stephans K, Tendulkar R, Xia P. Relationship of imaging frequency and planning margin to account for intrafraction prostate motion: analysis based on real-time monitoring data. Int J Radiat Oncol Biol Phys 2013; 85: 700-6. doi: 10.1016/j.ijrobp.2012.05.044
    • (2013) Int J Radiat Oncol Biol Phys , vol.85 , pp. 700-706
    • Curtis, W.1    Khan, M.2    Magnelli, A.3    Stephans, K.4    Tendulkar, R.5    Xia, P.6
  • 38
    • 84859879931 scopus 로고    scopus 로고
    • Patient-specific three-dimensional concomitant dose from cone beam computed tomography exposure in image-guided radiotherapy
    • Spezi E, Downes P, Jarvis R, Radu E, Staffurth J. Patient-specific three-dimensional concomitant dose from cone beam computed tomography exposure in image-guided radiotherapy. Int J Radiat Oncol Biol Phys 2012; 83: 419-26. doi: 10.1016/j. ijrobp.2011.06.1972
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , pp. 419-426
    • Spezi, E.1    Downes, P.2    Jarvis, R.3    Radu, E.4    Staffurth, J.5
  • 39
    • 84876138779 scopus 로고    scopus 로고
    • Imaging doses and secondary cancer risk from kilo-voltage cone-beam CT in radiation therapy
    • Kim DW, Chung WK, Yoon M. Imaging doses and secondary cancer risk from kilo-voltage cone-beam CT in radiation therapy. Health Phys 2013; 104: 499-503. doi: 10.1097/HP.0b013e318285c685
    • (2013) Health Phys , vol.104 , pp. 499-503
    • Kim, D.W.1    Chung, W.K.2    Yoon, M.3
  • 40
    • 0031777574 scopus 로고    scopus 로고
    • Intra-and inter-observer variability in contouring prostate and seminal vesicles: Implications for conformal treatment planning
    • Fiorino C, Reni M, Bolognesi A, Cattaneo GM, Calandrino R. Intra-and inter-observer variability in contouring prostate and seminal vesicles: implications for conformal treatment planning. Radiother Oncol 1998; 47: 285-92.
    • (1998) Radiother Oncol , vol.47 , pp. 285-292
    • Fiorino, C.1    Reni, M.2    Bolognesi, A.3    Cattaneo, G.M.4    Calandrino, R.5
  • 41
    • 0028784185 scopus 로고
    • Evaluation of changes in the size and location of the prostate, seminal vesicles, bladder, and rectum during a course of external beam radiation therapy
    • Roeske JC, Forman JD, Mesina CF, He T, Pelizzari CA, Fontenla E, et al. Evaluation of changes in the size and location of the prostate, seminal vesicles, bladder, and rectum during a course of external beam radiation therapy. Int J Radiat Oncol Biol Phys 1995; 33: 1321-9.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , pp. 1321-1329
    • Roeske, J.C.1    Forman, J.D.2    Mesina, C.F.3    He, T.4    Pelizzari, C.A.5    Fontenla, E.6
  • 42
    • 59649087394 scopus 로고    scopus 로고
    • The role of seminal vesicle motion in target margin assessment for online image-guided radiotherapy for prostate cancer
    • Liang J, Wu Q, Yan D. The role of seminal vesicle motion in target margin assessment for online image-guided radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 2009; 73: 935-43. doi: 10.1016/j. ijrobp.2008.10.019
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 935-943
    • Liang, J.1    Wu, Q.2    Yan, D.3
  • 43
    • 0042890340 scopus 로고    scopus 로고
    • Limitations of a convolution method for modeling geometric uncertainties in radiation therapy. I. The effect of shift invariance
    • Craig T, Battista J, van Dyk J. Limitations of a convolution method for modeling geometric uncertainties in radiation therapy. I. The effect of shift invariance. Med Phys 2003; 30: 2001-11.
    • (2003) Med Phys , vol.30 , pp. 2001-2011
    • Craig, T.1    Battista, J.2    Van Dyk, J.3
  • 44
    • 77956599240 scopus 로고    scopus 로고
    • Normal tissue complication probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: A test of the QUANTEC-recommended NTCP model
    • Liu M, Moiseenko V, Agranovich A, Karvat A, Kwan W, Saleh ZH, et al. Normal tissue complication probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: a test of the QUANTEC-recommended NTCP model. Acta Oncol 2010; 49: 1040-4. doi: 10.3109/0284186X.2010.509736
    • (2010) Acta Oncol , vol.49 , pp. 1040-1044
    • Liu, M.1    Moiseenko, V.2    Agranovich, A.3    Karvat, A.4    Kwan, W.5    Zh, S.6
  • 45
    • 84857913514 scopus 로고    scopus 로고
    • Parameters for the Lyman Kutcher Burman (LKB) model of normal tissue complication probability (NTCP) for specific rectal complications observed in clinical practise
    • Gulliford SL, Partridge M, Sydes MR, Webb S, Evans PM, Dearnaley DP. Parameters for the Lyman Kutcher Burman (LKB) model of normal tissue complication probability (NTCP) for specific rectal complications observed in clinical practise. Radiother Oncol 2012; 102: 347-51. doi: 10.1016/j. radonc.2011.10.022
    • (2012) Radiother Oncol , vol.102 , pp. 347-351
    • Gulliford, S.L.1    Partridge, M.2    Sydes, M.R.3    Webb, S.4    Evans, P.M.5    Dearnaley, D.P.6
  • 46
    • 0036140325 scopus 로고    scopus 로고
    • Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue
    • Brenner DJ, Martinez AA, Edmundson GK, Mitchell C, Thames HD, Armour EP. Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue. Int J Radiat Oncol Biol Phys 2002; 52: 6-13.
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 6-13
    • Brenner, D.J.1    Martinez, A.A.2    Edmundson, G.K.3    Mitchell, C.4    Thames, H.D.5    Armour, E.P.6
  • 47
    • 79955470532 scopus 로고    scopus 로고
    • Radiobiological impact of reduced margins and treatment technique for prostate cancer in terms of tumor control probability (TCP) and normal tissue complication probability (NTCP)
    • Jensen I, Carl J, Lund B, Larsen EH, Nielsen J. Radiobiological impact of reduced margins and treatment technique for prostate cancer in terms of tumor control probability (TCP) and normal tissue complication probability (NTCP). Med Dosim 2011; 36: 130-7. doi: 10.1016/j.meddos.2010.02.004
    • (2011) Med Dosim , vol.36 , pp. 130-137
    • Jensen, I.1    Carl, J.2    Lund, B.3    Larsen, E.H.4    Nielsen, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.