Bioconcentration, metabolism and neurotoxicity of the organophorous flame retardant 1,3-dichloro 2-propyl phosphate (TDCPP) to zebrafish

Aquatic Toxicology

Volumn 158, Issue , 2015, Pages 108-115

  Wang, Qiangwei ^a,b   Lam, James Chung Wah ^c,d   Man, Yin Chung ^c,d   Lai, Nelson Lok Shun ^c,d   Kwok, Karen Ying ^c,d   Guo, Yong yong ^a   Lam, Paul Kwan Sing ^c,d   Zhou, Bingsheng ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d Research Institute Building   (Hong Kong)

Author keywords

Bioconcentration and metabolism; Gender specific toxicity; Neurotoxicity; TDCPP; Zebrafish

Indexed keywords

ACETYLCHOLINESTERASE; BIS(1,3 DICHLORO 2 PROPYL)PHOSPHATE; DOPAMINE; FLAME RETARDANT; GLIAL FIBRILLARY ACIDIC PROTEIN; MALTOSE BINDING PROTEIN; MESSENGER RNA; NEUROMODULIN; NEUROTRANSMITTER; SEROTONIN; TRIS(1,3 DICHLORO 2 PROPYL) PHOSPHATE; UNCLASSIFIED DRUG; ORGANOPHOSPHORUS COMPOUND; TRIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE; WATER POLLUTANT;

BIOACCUMULATION; EMBRYO; FISH; MATURATION; METABOLISM; ORGANOPHOSPHATE; PROTEIN; RNA; TOXICITY;

ADULT; ALPHA1 TUBULIN GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUATIC SPECIES; ARTICLE; BIOACCUMULATION; BODY BURDEN; BRAIN LEVEL; CHEMICAL STRESS; CONCENTRATION (PARAMETERS); CONTAMINATED FISH; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOPAMINE BRAIN LEVEL; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; FEMALE; GAP 43 GENE; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GFAP GENE; LOCOMOTION; LONG TERM EXPOSURE; MALE; MBP GENE; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; SEROTONIN BRAIN LEVEL; SEX DIFFERENCE; SYN2A GENE; TOXICOLOGY; UPREGULATION; ZEBRA FISH; ANALYSIS; ANIMAL; ANIMAL EMBRYO; BRAIN; CHEMISTRY; DRUG EFFECTS; EMBRYOLOGY; ENVIRONMENTAL EXPOSURE; GENETICS; METABOLISM; NERVOUS SYSTEM; PHYSIOLOGY; TOXICITY; WATER POLLUTANT;

DANIO RERIO;

ANIMALS; BRAIN; EMBRYO, NONMAMMALIAN; ENVIRONMENTAL EXPOSURE; FEMALE; FLAME RETARDANTS; GENE EXPRESSION REGULATION; MALE; NERVOUS SYSTEM; ORGANOPHOSPHORUS COMPOUNDS; RNA, MESSENGER; SEX FACTORS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

EID: 84911891784     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2014.11.001     Document Type: Article

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