Testosterone increases renal anti-aging klotho gene expression via the androgen receptor-mediated pathway

Biochemical Journal

Volumn 464, Issue 2, 2014, Pages 221-229

  Hsu, Shih Che ^a   Huang, Shih Ming ^a   Lin, Shih Hua ^a,b   Ka, Shuk Man ^b   Chen, Ann ^b   Shih, Meng Fu ^c   Hsu, Yu Juei ^a,b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Aging; Androgen; Androgen receptor; Klotho

Indexed keywords

ANDROGEN RECEPTOR; FLUTAMIDE; KLOTHO PROTEIN; MESSENGER RNA; TESTOSTERONE; BETA GLUCURONIDASE; ESTROGEN;

ANDROGEN RESPONSE ELEMENT; ANDROGEN THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; KIDNEY EPITHELIUM; MALE; MOUSE; NONHUMAN; NRK 52E CELL; PROMOTER REGION; PROTEIN BINDING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TESTOSTERONE BLOOD LEVEL; UPREGULATION; AGING; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LONGEVITY; METABOLISM;

AGING; ANIMALS; ESTROGENS; FLUTAMIDE; GENE EXPRESSION REGULATION; GLUCURONIDASE; KIDNEY; LONGEVITY; MALE; MICE; PROMOTER REGIONS, GENETIC; RECEPTORS, ANDROGEN; RESPONSE ELEMENTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TESTOSTERONE;

EID: 84911867793     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140739     Document Type: Article

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