Sonic hedgehog and androgen signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer

Scandinavian Journal of Urology

Volumn 48, Issue 6, 2014, Pages 523-532

  Yamamichi, Fukashi ^a   Shigemura, Katsumi ^a   Behnsawy, Hosny M ^a,c   Meligy, Fatma Y ^a,d,e   Huang, Wen Chin ^c   Li, Xiangyan ^c   Yamanaka, Kunito ^a   Hanioka, Keisuke ^d   Miyake, Hideaki ^a   Tanaka, Kazushi ^a   Kawabata, Masato ^b   Shirakawa, Toshiro ^a,b   Fujisawa, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c Department of Urology ^*  (Japan)

^d Akashi Municipal Hospital   (Japan)

^e Assiut University Faculty of Medicine   (Egypt)

Author keywords

Androgens; Epithelial mesenchymal transition; Prostate cancer; Prostate epithelial and stroma; Sonic hedgehog.

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; CYCLOPAMINE; NERVE CELL ADHESION MOLECULE; OSTEONECTIN; PROSTATE SPECIFIC ANTIGEN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UVOMORULIN; VIMENTIN; CADHERIN; CULTURE MEDIUM; GLI1 PROTEIN, HUMAN; SHH PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VERATRUM ALKALOID;

ARTICLE; CANCER GROWTH; CANCER PATIENT; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GLEASON SCORE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LNCAP CELL LINE; MALE; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECTS; EPITHELIUM CELL; FIBROBLAST; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; PHARMACOLOGY; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CADHERINS; CELL LINE, TUMOR; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; DIHYDROTESTOSTERONE; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROBLASTS; GENE EXPRESSION; HEDGEHOG PROTEINS; HUMANS; MALE; OSTEONECTIN; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION; STROMAL CELLS; TRANSCRIPTION FACTORS; VERATRUM ALKALOIDS; VIMENTIN;

EID: 84911861854     PISSN: 21681805     EISSN: 21681813     Source Type: Journal    
DOI: 10.3109/21681805.2014.898336     Document Type: Article

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