Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells

Prostate

Volumn 71, Issue 16, 2011, Pages 1711-1722

  Shigemura, Katsumi ^a,d   Huang, Wen Chin ^a,b   Li, Xiangyan ^b   Zhau, Haiyen E ^a,b   Zhu, Guodong ^a   Gotoh, Akinobu ^c   Fujisawa, Masato ^d   Xie, Jingwu ^e   Marshall, Fray F ^a   Chung, Leland W K ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e University of Texas Medical Branch School of Medicine   (United States)

Author keywords

androgen independent prostate cancer; bone marrow stroma; prostate stroma; Sonic hedgehog; tumor stromal interaction

Indexed keywords

ANDROGEN; CYCLOPAMINE; MESSENGER RNA; OSTEONECTIN; PROSTATE SPECIFIC ANTIGEN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BONE MARROW CELL; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL GROWTH; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; FIBROBLAST; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROMA CELL; UPREGULATION;

ANDROGENS; ANIMALS; BONE MARROW CELLS; CELL COMMUNICATION; CELL LINE, TUMOR; CHIMERA; CULTURE MEDIA, CONDITIONED; FIBROBLASTS; HEDGEHOG PROTEINS; HUMANS; MALE; MICE; MICE, MUTANT STRAINS; PARACRINE COMMUNICATION; PROSTATE; PROSTATIC NEOPLASMS; STROMAL CELLS; TRANSCRIPTION FACTORS; VERATRUM ALKALOIDS;

EID: 80054066295     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21388     Document Type: Article

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