메뉴 건너뛰기




Volumn 105, Issue 11, 2014, Pages 1496-1502

Expression of L-type amino acid transporter 1 (LAT1) as a prognostic and therapeutic indicator in multiple myeloma

Author keywords

CD98; L type amino acid transporter 1; Melphalan; Multiple myeloma; Prognosis

Indexed keywords

AMINO ACID TRANSPORTER; ANTINEOPLASTIC AGENT; CD98 ANTIGEN;

EID: 84911458266     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12529     Document Type: Article
Times cited : (53)

References (47)
  • 1
    • 0023741488 scopus 로고
    • Value of beta 2-microglobulin level and plasma cell labeling indices as prognostic factors in patients with newly diagnosed myeloma
    • Greipp PR, Katzmann JA, O'Fallon WM et al. Value of beta 2-microglobulin level and plasma cell labeling indices as prognostic factors in patients with newly diagnosed myeloma. Blood 1988; 72: 219-23.
    • (1988) Blood , vol.72 , pp. 219-223
    • Greipp, P.R.1    Katzmann, J.A.2    O'Fallon, W.M.3
  • 2
    • 70149107680 scopus 로고    scopus 로고
    • Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone
    • Kapoor P, Kumar S, Fonseca R et al. Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone. Blood 2009; 114: 518-21.
    • (2009) Blood , vol.114 , pp. 518-521
    • Kapoor, P.1    Kumar, S.2    Fonseca, R.3
  • 3
    • 0038495926 scopus 로고    scopus 로고
    • Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression
    • Shaughnessy J, Jacobson J, Sawyer J et al. Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression. Blood 2003; 101: 3849-56.
    • (2003) Blood , vol.101 , pp. 3849-3856
    • Shaughnessy, J.1    Jacobson, J.2    Sawyer, J.3
  • 4
    • 0021752735 scopus 로고
    • Low plasma cell 3(H) thymidine incorporation in monoclonal gammopathy of undetermined significance (MGUS), smouldering myeloma and remission phase myeloma: a reliable indicator of patients not requiring therapy
    • Boccadoro M, Gavarotti P, Fossati G et al. Low plasma cell 3(H) thymidine incorporation in monoclonal gammopathy of undetermined significance (MGUS), smouldering myeloma and remission phase myeloma: a reliable indicator of patients not requiring therapy. Br J Haematol 1984; 58: 689-96.
    • (1984) Br J Haematol , vol.58 , pp. 689-696
    • Boccadoro, M.1    Gavarotti, P.2    Fossati, G.3
  • 5
    • 0022547494 scopus 로고
    • Determination of the plasma cell labelling index with bromodeoxyuridine in a double fluorescence technique
    • Lokhorst HM, Boom SE, Bast BJ et al. Determination of the plasma cell labelling index with bromodeoxyuridine in a double fluorescence technique. Br J Haematol 1986; 64: 271-5.
    • (1986) Br J Haematol , vol.64 , pp. 271-275
    • Lokhorst, H.M.1    Boom, S.E.2    Bast, B.J.3
  • 6
    • 0842327296 scopus 로고    scopus 로고
    • Ki-67 proliferation index: correlation with prognostic parameters and outcome in multiple myeloma
    • Alexandrakis MG, Passam FH, Kyriakou DS et al. Ki-67 proliferation index: correlation with prognostic parameters and outcome in multiple myeloma. Am J Clin Oncol 2004; 27: 8-13.
    • (2004) Am J Clin Oncol , vol.27 , pp. 8-13
    • Alexandrakis, M.G.1    Passam, F.H.2    Kyriakou, D.S.3
  • 7
    • 34548561645 scopus 로고    scopus 로고
    • Plasma cell growth fraction using Ki-67 antigen expression identifies a subgroup of multiple myeloma patients displaying short survival within the ISS stage I
    • Gastinne T, Leleu X, Duhamel A et al. Plasma cell growth fraction using Ki-67 antigen expression identifies a subgroup of multiple myeloma patients displaying short survival within the ISS stage I. Eur J Haematol 2007; 79: 297-304.
    • (2007) Eur J Haematol , vol.79 , pp. 297-304
    • Gastinne, T.1    Leleu, X.2    Duhamel, A.3
  • 8
    • 78650981539 scopus 로고    scopus 로고
    • Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma
    • Hose D, Rème T, Hielscher T et al. Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma. Haematologica 2011; 96: 87-95.
    • (2011) Haematologica , vol.96 , pp. 87-95
    • Hose, D.1    Rème, T.2    Hielscher, T.3
  • 9
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen HN. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 1990; 70: 43-77.
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 10
    • 0028205533 scopus 로고
    • Regulatory and molecular aspects of mammalian amino acid transport
    • McGivan JD, Pastor-Anglada M. Regulatory and molecular aspects of mammalian amino acid transport. Biochem J 1994; 299: 321-34.
    • (1994) Biochem J , vol.299 , pp. 321-334
    • McGivan, J.D.1    Pastor-Anglada, M.2
  • 11
    • 0032508585 scopus 로고    scopus 로고
    • Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)
    • Kanai Y, Segawa H, Miyamoto K et al. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J Biol Chem 1998; 273: 23629-32.
    • (1998) J Biol Chem , vol.273 , pp. 23629-23632
    • Kanai, Y.1    Segawa, H.2    Miyamoto, K.3
  • 12
    • 4243389920 scopus 로고    scopus 로고
    • Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
    • Yanagida O, Kanai Y, Chairoungdua A et al. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta 2001; 1514: 291-302.
    • (2001) Biochim Biophys Acta , vol.1514 , pp. 291-302
    • Yanagida, O.1    Kanai, Y.2    Chairoungdua, A.3
  • 13
    • 39449101130 scopus 로고    scopus 로고
    • Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer
    • Kaira K, Oriuchi N, Imai H et al. Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer. Br J Cancer 2008a; 98: 742-8.
    • (2008) Br J Cancer , vol.98 , pp. 742-748
    • Kaira, K.1    Oriuchi, N.2    Imai, H.3
  • 14
    • 33646540633 scopus 로고    scopus 로고
    • L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors
    • Nawashiro H, Otani N, Shinomiya N et al. L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors. Int J Cancer 2006; 119: 484-92.
    • (2006) Int J Cancer , vol.119 , pp. 484-492
    • Nawashiro, H.1    Otani, N.2    Shinomiya, N.3
  • 15
    • 57649185073 scopus 로고    scopus 로고
    • L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer
    • Sakata T, Ferdous G, Tsuruta T et al. L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer. Pathol Int 2009; 59: 7-18.
    • (2009) Pathol Int , vol.59 , pp. 7-18
    • Sakata, T.1    Ferdous, G.2    Tsuruta, T.3
  • 16
    • 79955017462 scopus 로고    scopus 로고
    • High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: comparison with non-cancerous lesions
    • Ichinoe M, Mikami T, Yoshida T et al. High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: comparison with non-cancerous lesions. Pathol Int 2011; 61: 281-9.
    • (2011) Pathol Int , vol.61 , pp. 281-289
    • Ichinoe, M.1    Mikami, T.2    Yoshida, T.3
  • 17
    • 84864879465 scopus 로고    scopus 로고
    • Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer
    • Kaira K, Sunose Y, Arakawa K et al. Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer. Br J Cancer 2012; 107: 632-8.
    • (2012) Br J Cancer , vol.107 , pp. 632-638
    • Kaira, K.1    Sunose, Y.2    Arakawa, K.3
  • 18
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders
    • International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders. Br J Haematol 2003; 121: 749-57.
    • (2003) Br J Haematol , vol.121 , pp. 749-757
  • 19
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
    • Durie BG, Salmon SE. A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975; 36: 842-54.
    • (1975) Cancer , vol.36 , pp. 842-854
    • Durie, B.G.1    Salmon, S.E.2
  • 20
    • 20644460600 scopus 로고    scopus 로고
    • International staging system for multiple myeloma
    • Greipp PR, San Miguel J, Durie BG et al. International staging system for multiple myeloma. J Clin Oncol, 2005; 23: 3412-20.
    • (2005) J Clin Oncol , vol.23 , pp. 3412-3420
    • Greipp, P.R.1    San Miguel, J.2    Durie, B.G.3
  • 21
    • 57349177871 scopus 로고    scopus 로고
    • L-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms
    • Kaira K, Oriuchi N, Imai H et al. L-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms. Cancer Sci 2008b; 99: 2380-6.
    • (2008) Cancer Sci , vol.99 , pp. 2380-2386
    • Kaira, K.1    Oriuchi, N.2    Imai, H.3
  • 22
    • 0036066144 scopus 로고    scopus 로고
    • Proliferation, apoptosis, and intratumoral vascularity in multiple myeloma: correlation with the clinical stage and cytological grade
    • Xu JL, Lai R, Kinoshita T et al. Proliferation, apoptosis, and intratumoral vascularity in multiple myeloma: correlation with the clinical stage and cytological grade. J Clin Pathol 2002; 55: 530-4.
    • (2002) J Clin Pathol , vol.55 , pp. 530-534
    • Xu, J.L.1    Lai, R.2    Kinoshita, T.3
  • 23
    • 0042529207 scopus 로고    scopus 로고
    • Expression of neutral amino acid transporter ASCT2 in human prostate
    • Li R, Younes M, Frolov A et al. Expression of neutral amino acid transporter ASCT2 in human prostate. Anticancer Res 2003; 23: 3413-8.
    • (2003) Anticancer Res , vol.23 , pp. 3413-3418
    • Li, R.1    Younes, M.2    Frolov, A.3
  • 24
    • 0036765406 scopus 로고    scopus 로고
    • Overexpression of the neutral amino acid transporter ASCT2 in human colorectal adenocarcinoma
    • Witte D, Ali N, Carlson N et al. Overexpression of the neutral amino acid transporter ASCT2 in human colorectal adenocarcinoma. Anticancer Res 2002; 22: 2555-7.
    • (2002) Anticancer Res , vol.22 , pp. 2555-2557
    • Witte, D.1    Ali, N.2    Carlson, N.3
  • 25
    • 0014236097 scopus 로고
    • Melphalan therapy for plasma cell myeloma
    • Alexanian R, Bergsagel DE, Migliore PJ et al. Melphalan therapy for plasma cell myeloma. Blood 1968; 31: 1-10.
    • (1968) Blood , vol.31 , pp. 1-10
    • Alexanian, R.1    Bergsagel, D.E.2    Migliore, P.J.3
  • 26
    • 79954448518 scopus 로고    scopus 로고
    • Melphalan and prednisone versus melphalan, prednisone and thalidomide for elderly and/or transplant ineligible patients with multiple myeloma: a meta-analysis
    • Kapoor P, Rajkumar SV, Dispenzieri A et al. Melphalan and prednisone versus melphalan, prednisone and thalidomide for elderly and/or transplant ineligible patients with multiple myeloma: a meta-analysis. Leukemia 2011; 25: 689-96.
    • (2011) Leukemia , vol.25 , pp. 689-696
    • Kapoor, P.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 27
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva NK et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med, 2008; 359: 906-17.
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 28
    • 0018668451 scopus 로고
    • The chemotherapy on plasma-cell myeloma and the incidence of acute leukemia
    • Bergsagel DE, Bailey AJ, Langley GR et al. The chemotherapy on plasma-cell myeloma and the incidence of acute leukemia. N Engl J Med 1979; 301: 743-8.
    • (1979) N Engl J Med , vol.301 , pp. 743-748
    • Bergsagel, D.E.1    Bailey, A.J.2    Langley, G.R.3
  • 29
    • 0023198180 scopus 로고
    • A comparison of the incidence of the myelodysplastic syndrome and acute myeloid leukaemia following melphalan and cyclophosphamide treatment for myelomatosis
    • Cuzick J, Erskine S, Edelman D et al. A comparison of the incidence of the myelodysplastic syndrome and acute myeloid leukaemia following melphalan and cyclophosphamide treatment for myelomatosis. Br J Cancer 1987; 55: 523-9.
    • (1987) Br J Cancer , vol.55 , pp. 523-529
    • Cuzick, J.1    Erskine, S.2    Edelman, D.3
  • 30
    • 0030924408 scopus 로고    scopus 로고
    • Factors influencing collection of peripheral blood progenitor cells following high-dose cyclophosphamide and granulocyte colony-stimulating factor in patients with multiple myeloma
    • Goldschmidt H, Hegenbart U, Wallmeier M et al. Factors influencing collection of peripheral blood progenitor cells following high-dose cyclophosphamide and granulocyte colony-stimulating factor in patients with multiple myeloma. Br J Haematol 1997; 98: 736-44.
    • (1997) Br J Haematol , vol.98 , pp. 736-744
    • Goldschmidt, H.1    Hegenbart, U.2    Wallmeier, M.3
  • 31
    • 0037303497 scopus 로고    scopus 로고
    • Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity
    • Kanai Y, Endou H. Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity. J Toxicol Sci 2003; 28: 1-17.
    • (2003) J Toxicol Sci , vol.28 , pp. 1-17
    • Kanai, Y.1    Endou, H.2
  • 32
    • 12144287436 scopus 로고    scopus 로고
    • L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma
    • Lin J, Raoof DA, Thomas DG et al. L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma. Neoplasia 2004; 6: 74-84.
    • (2004) Neoplasia , vol.6 , pp. 74-84
    • Lin, J.1    Raoof, D.A.2    Thomas, D.G.3
  • 33
    • 0033642321 scopus 로고    scopus 로고
    • Down-regulation of CD98 in melphalan-resistant myeloma cells with reduced drug uptake
    • Harada N, Nagasaki A, Hata H et al. Down-regulation of CD98 in melphalan-resistant myeloma cells with reduced drug uptake. Acta Haematol 2000; 103: 144-51.
    • (2000) Acta Haematol , vol.103 , pp. 144-151
    • Harada, N.1    Nagasaki, A.2    Hata, H.3
  • 34
    • 0023115893 scopus 로고
    • Sensitivity to melphalan as a function of transport activity and proliferative rate in BALB/c 3T3 fibroblasts
    • Blosmanis R, Wright JA, Goldenberg GJ. Sensitivity to melphalan as a function of transport activity and proliferative rate in BALB/c 3T3 fibroblasts. Cancer Res 1987; 47: 1273-7.
    • (1987) Cancer Res , vol.47 , pp. 1273-1277
    • Blosmanis, R.1    Wright, J.A.2    Goldenberg, G.J.3
  • 35
    • 84864570434 scopus 로고    scopus 로고
    • Darwinian evolution and tiding clones in multiple myeloma
    • Bahlis NJ. Darwinian evolution and tiding clones in multiple myeloma. Blood 2012; 120: 927-8.
    • (2012) Blood , vol.120 , pp. 927-928
    • Bahlis, N.J.1
  • 36
    • 33644833147 scopus 로고    scopus 로고
    • Thalidomide and hematopoietic-cell transplantation for multiple myeloma
    • Barlogie B, Tricot G, Anaissie E et al. Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N Engl J Med 2006; 354: 1021-30.
    • (2006) N Engl J Med , vol.354 , pp. 1021-1030
    • Barlogie, B.1    Tricot, G.2    Anaissie, E.3
  • 37
    • 37249040444 scopus 로고    scopus 로고
    • Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling
    • Haessler J, Shaughnessy JD Jr, Zhan F et al. Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling. Clin Cancer Res 2007; 13: 7073-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 7073-7079
    • Haessler, J.1    Shaughnessy, J.D.2    Zhan, F.3
  • 38
    • 33845974073 scopus 로고    scopus 로고
    • Complete response in myeloma extends survival without, but not with history of prior monoclonal gammopathy of undetermined significance or smouldering disease
    • Pineda-Roman M, Bolejack V, Arzoumanian V et al. Complete response in myeloma extends survival without, but not with history of prior monoclonal gammopathy of undetermined significance or smouldering disease. Br J Haematol 2007; 136: 393-9.
    • (2007) Br J Haematol , vol.136 , pp. 393-399
    • Pineda-Roman, M.1    Bolejack, V.2    Arzoumanian, V.3
  • 39
    • 33745779502 scopus 로고    scopus 로고
    • The molecular classification of multiple myeloma
    • Zhan F, Huang Y, Colla S et al. The molecular classification of multiple myeloma. Blood 2006; 108: 2020-8.
    • (2006) Blood , vol.108 , pp. 2020-2028
    • Zhan, F.1    Huang, Y.2    Colla, S.3
  • 40
    • 77956060344 scopus 로고    scopus 로고
    • 11C-methionine (MET) uptake with L-type amino acid transporter 1 in human gliomas
    • 11C-methionine (MET) uptake with L-type amino acid transporter 1 in human gliomas. J Neurooncol 2010; 99: 217-25.
    • (2010) J Neurooncol , vol.99 , pp. 217-225
    • Okubo, S.1    Zhen, H.N.2    Kawai, N.3
  • 41
    • 84864755188 scopus 로고    scopus 로고
    • Transport of 3-fluoro-L-α-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET
    • Wiriyasermkul P, Nagamori S, Tominaga H et al. Transport of 3-fluoro-L-α-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET. J Nucl Med 2012; 53: 1253-61.
    • (2012) J Nucl Med , vol.53 , pp. 1253-1261
    • Wiriyasermkul, P.1    Nagamori, S.2    Tominaga, H.3
  • 42
    • 84876473907 scopus 로고    scopus 로고
    • Prognostic implications of serial 18-fluoro-deoxyglucose emission tomography in multiple myeloma treated with total therapy 3
    • Usmani SZ, Mitchell A, Waheed S et al. Prognostic implications of serial 18-fluoro-deoxyglucose emission tomography in multiple myeloma treated with total therapy 3. Blood 2013; 121: 1819-23.
    • (2013) Blood , vol.121 , pp. 1819-1823
    • Usmani, S.Z.1    Mitchell, A.2    Waheed, S.3
  • 43
    • 82955189267 scopus 로고    scopus 로고
    • Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation
    • Zamagni E, Patriarca F, Nanni C et al. Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation. Blood 2011; 118: 5989-95.
    • (2011) Blood , vol.118 , pp. 5989-5995
    • Zamagni, E.1    Patriarca, F.2    Nanni, C.3
  • 45
    • 35948940869 scopus 로고    scopus 로고
    • Fluorine-18-α-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study
    • Kaira K, Oriuchi N, Otani Y et al. Fluorine-18-α-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study. Clin Cancer Res 2007; 13: 6369-78.
    • (2007) Clin Cancer Res , vol.13 , pp. 6369-6378
    • Kaira, K.1    Oriuchi, N.2    Otani, Y.3
  • 46
    • 84885423533 scopus 로고    scopus 로고
    • 18F-FAMT PET and L-type amino acid transporter 1 (LAT1) expression in oral squamous cell carcinoma
    • 18F-FAMT PET and L-type amino acid transporter 1 (LAT1) expression in oral squamous cell carcinoma. Eur J Nucl Med Mol Imaging 2013; 40: 1692-700.
    • (2013) Eur J Nucl Med Mol Imaging , vol.40 , pp. 1692-1700
    • Nobusawa, A.1    Kim, M.2    Kaira, K.3
  • 47
    • 79952042047 scopus 로고    scopus 로고
    • Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study
    • Ghobrial IM, Weller E, Vij R et al. Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study. Lancet Oncol 2011; 12: 263-72.
    • (2011) Lancet Oncol , vol.12 , pp. 263-272
    • Ghobrial, I.M.1    Weller, E.2    Vij, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.