메뉴 건너뛰기




Volumn 9, Issue 11, 2014, Pages

Evidence for SH2 domain-containing 5′ -Inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SHIP2; PROTEIN TYROSINE PHOSPHATASE SHP; REGULATOR PROTEIN; UNCLASSIFIED DRUG; HGF PROTEIN, HUMAN; INPPL1 PROTEIN, HUMAN; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHATASE; SCATTER FACTOR;

EID: 84911453582     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112548     Document Type: Article
Times cited : (13)

References (59)
  • 1
    • 81255188905 scopus 로고    scopus 로고
    • The lymphatic vasculature in disease
    • Alitalo K (2011) The lymphatic vasculature in disease. Nat Med 17: 1371-1380.
    • (2011) Nat Med , vol.17 , pp. 1371-1380
    • Alitalo, K.1
  • 2
    • 41749093830 scopus 로고    scopus 로고
    • Molecular biology and pathology of lymphangiogenesis
    • Karpanen T, Alitalo K (2008) Molecular biology and pathology of lymphangiogenesis. Annu Rev Pathol 3: 367-397.
    • (2008) Annu Rev Pathol , vol.3 , pp. 367-397
    • Karpanen, T.1    Alitalo, K.2
  • 3
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • Tammela T, Alitalo K (2010) Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140: 460-476.
    • (2010) Cell , vol.140 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 4
    • 84896768295 scopus 로고    scopus 로고
    • New developments in clinical aspects of lymphatic disease
    • Mortimer PS, Rockson SG (2014) New developments in clinical aspects of lymphatic disease. J Clin Invest 124: 915-921.
    • (2014) J Clin Invest , vol.124 , pp. 915-921
    • Mortimer, P.S.1    Rockson, S.G.2
  • 5
    • 0033646615 scopus 로고    scopus 로고
    • Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome
    • Fang J, Dagenais SL, Erickson RP, Arlt MF, Glynn MW, et al. (2000) Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome. Am J Hum Genet 67: 1382-1388.
    • (2000) Am J Hum Genet , vol.67 , pp. 1382-1388
    • Fang, J.1    Dagenais, S.L.2    Erickson, R.P.3    Arlt, M.F.4    Glynn, M.W.5
  • 6
    • 0038353732 scopus 로고    scopus 로고
    • Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia
    • Irrthum A, Devriendt K, Chitayat D, Matthijs G, Glade C, et al. (2003) Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. Am J Hum Genet 72: 1470-1478.
    • (2003) Am J Hum Genet , vol.72 , pp. 1470-1478
    • Irrthum, A.1    Devriendt, K.2    Chitayat, D.3    Matthijs, G.4    Glade, C.5
  • 8
    • 70649091987 scopus 로고    scopus 로고
    • Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans
    • Alders M, Hogan BM, Gjini E, Salehi F, Al-Gazali L, et al. (2009) Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans. Nat Genet 41: 1272-1274.
    • (2009) Nat Genet , vol.41 , pp. 1272-1274
    • Alders, M.1    Hogan, B.M.2    Gjini, E.3    Salehi, F.4    Al-Gazali, L.5
  • 9
    • 84857061433 scopus 로고    scopus 로고
    • Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy
    • Ostergaard P, Simpson MA, Mendola A, Vasudevan P, Connell FC, et al. (2012) Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy. Am J Hum Genet 90: 356-362.
    • (2012) Am J Hum Genet , vol.90 , pp. 356-362
    • Ostergaard, P.1    Simpson, M.A.2    Mendola, A.3    Vasudevan, P.4    Connell, F.C.5
  • 11
    • 84859867164 scopus 로고    scopus 로고
    • Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment
    • Finegold DN, Baty CJ, Knickelbein KZ, Perschke S, Noon SE, et al. (2012) Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment. Clin Cancer Res 18: 2382-2390.
    • (2012) Clin Cancer Res , vol.18 , pp. 2382-2390
    • Finegold, D.N.1    Baty, C.J.2    Knickelbein, K.Z.3    Perschke, S.4    Noon, S.E.5
  • 12
    • 80053385569 scopus 로고    scopus 로고
    • Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
    • Ostergaard P, Simpson MA, Connell FC, Steward CG, Brice G, et al. (2011) Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet 43: 929-931.
    • (2011) Nat Genet , vol.43 , pp. 929-931
    • Ostergaard, P.1    Simpson, M.A.2    Connell, F.C.3    Steward, C.G.4    Brice, G.5
  • 14
    • 84875209848 scopus 로고    scopus 로고
    • Mutation in vascular endothelial growth factor-C, a ligand for vascular endothelial growth factor receptor-3, is associated with autosomal dominant milroy-like primary lymphedema
    • Gordon K, Schulte D, Brice G, Simpson MA, Roukens MG, et al. (2013) Mutation in vascular endothelial growth factor-C, a ligand for vascular endothelial growth factor receptor-3, is associated with autosomal dominant milroy-like primary lymphedema. Circ Res 112: 956-960.
    • (2013) Circ Res , vol.112 , pp. 956-960
    • Gordon, K.1    Schulte, D.2    Brice, G.3    Simpson, M.A.4    Roukens, M.G.5
  • 18
    • 70349306570 scopus 로고    scopus 로고
    • Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha
    • Mouta-Bellum C, Kirov A, Miceli-Libby L, Mancini ML, Petrova TV, et al. (2009) Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Dev Dyn 238: 2670-2679.
    • (2009) Dev Dyn , vol.238 , pp. 2670-2679
    • Mouta-Bellum, C.1    Kirov, A.2    Miceli-Libby, L.3    Mancini, M.L.4    Petrova, T.V.5
  • 19
    • 34249026448 scopus 로고    scopus 로고
    • Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice
    • Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, et al. (2007) Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell 129: 957-968.
    • (2007) Cell , vol.129 , pp. 957-968
    • Gupta, S.1    Ramjaun, A.R.2    Haiko, P.3    Wang, Y.4    Warne, P.H.5
  • 20
    • 77957365795 scopus 로고    scopus 로고
    • Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development
    • Zhou F, Chang Z, Zhang L, Hong YK, Shen B, et al. (2010) Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development. Am J Pathol 177: 2124-2133.
    • (2010) Am J Pathol , vol.177 , pp. 2124-2133
    • Zhou, F.1    Chang, Z.2    Zhang, L.3    Hong, Y.K.4    Shen, B.5
  • 22
    • 16844383228 scopus 로고    scopus 로고
    • SH2-containing 5′-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor
    • Prasad NK, Decker SJ (2005) SH2-containing 5′-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor. J Biol Chem 280: 13129-13136.
    • (2005) J Biol Chem , vol.280 , pp. 13129-13136
    • Prasad, N.K.1    Decker, S.J.2
  • 23
    • 0345688084 scopus 로고    scopus 로고
    • SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: Their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels
    • Giuriato S, Pesesse X, Bodin S, Sasaki T, Viala C, et al. (2003) SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels. Biochem J 376: 199-207.
    • (2003) Biochem J , vol.376 , pp. 199-207
    • Giuriato, S.1    Pesesse, X.2    Bodin, S.3    Sasaki, T.4    Viala, C.5
  • 24
    • 77955291512 scopus 로고    scopus 로고
    • Regulation of SHIP2 function through plasma membrane interaction
    • Deneubourg L, Vanderwinden JM, Erneux C (2010) Regulation of SHIP2 function through plasma membrane interaction. Adv Enzyme Regul 50: 262-271.
    • (2010) Adv Enzyme Regul , vol.50 , pp. 262-271
    • Deneubourg, L.1    Vanderwinden, J.M.2    Erneux, C.3
  • 25
    • 78650400912 scopus 로고    scopus 로고
    • Human lymphatic architecture and dynamic transport imaged using nearinfrared fluorescence
    • Rasmussen JC, Tan IC, Marshall MV, Adams KE, Kwon S, et al. (2010) Human Lymphatic Architecture and Dynamic Transport Imaged Using Nearinfrared Fluorescence. Transl Oncol 3: 362-372.
    • (2010) Transl Oncol , vol.3 , pp. 362-372
    • Rasmussen, J.C.1    Tan, I.C.2    Marshall, M.V.3    Adams, K.E.4    Kwon, S.5
  • 27
    • 77951799158 scopus 로고    scopus 로고
    • Analysis of genetic inheritance in a family quartet by whole-genome sequencing
    • Roach JC, Glusman G, Smit AF, Huff CD, Hubley R, et al. (2010) Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science 328: 636-639.
    • (2010) Science , vol.328 , pp. 636-639
    • Roach, J.C.1    Glusman, G.2    Smit, A.F.3    Huff, C.D.4    Hubley, R.5
  • 29
    • 78449283134 scopus 로고    scopus 로고
    • Lymphedema beyond breast cancer: A systematic review and meta-analysis of cancer-related secondary lymphedema
    • Cormier JN, Askew RL, Mungovan KS, Xing Y, Ross MI, et al. (2010) Lymphedema beyond breast cancer: a systematic review and meta-analysis of cancer-related secondary lymphedema. Cancer 116: 5138-5149.
    • (2010) Cancer , vol.116 , pp. 5138-5149
    • Cormier, J.N.1    Askew, R.L.2    Mungovan, K.S.3    Xing, Y.4    Ross, M.I.5
  • 30
    • 30544452034 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes lymphatic vessel formation and function
    • Kajiya K, Hirakawa S, Ma B, Drinnenberg I, Detmar M (2005) Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 24: 2885-2895.
    • (2005) EMBO J , vol.24 , pp. 2885-2895
    • Kajiya, K.1    Hirakawa, S.2    Ma, B.3    Drinnenberg, I.4    Detmar, M.5
  • 31
    • 33748670727 scopus 로고    scopus 로고
    • Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis
    • Saito Y, Nakagami H, Morishita R, Takami Y, Kikuchi Y, et al. (2006) Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis. Circulation 114: 1177-1184.
    • (2006) Circulation , vol.114 , pp. 1177-1184
    • Saito, Y.1    Nakagami, H.2    Morishita, R.3    Takami, Y.4    Kikuchi, Y.5
  • 32
    • 84911363146 scopus 로고    scopus 로고
    • Lymphatic vessel abnormalities arising from disorders of ras signal transduction
    • Sevick-Muraca EM, King PD (2013) Lymphatic vessel abnormalities arising from disorders of Ras signal transduction. Trends Cardiovasc Med.
    • (2013) Trends Cardiovasc Med
    • Sevick-Muraca, E.M.1    King, P.D.2
  • 33
    • 19444363140 scopus 로고    scopus 로고
    • The SH2-domiancontaining inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading
    • Koch A, Mancini A, El Bounkari O, Tamura T (2005) The SH2-domiancontaining inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading. Oncogene 24: 3436-3447.
    • (2005) Oncogene , vol.24 , pp. 3436-3447
    • Koch, A.1    Mancini, A.2    El Bounkari, O.3    Tamura, T.4
  • 34
    • 38849148269 scopus 로고    scopus 로고
    • Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover
    • Prasad NK, Tandon M, Badve S, Snyder PW, Nakshatri H (2008) Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover. Carcinogenesis 29: 25-34.
    • (2008) Carcinogenesis , vol.29 , pp. 25-34
    • Prasad, N.K.1    Tandon, M.2    Badve, S.3    Snyder, P.W.4    Nakshatri, H.5
  • 35
    • 84856540111 scopus 로고    scopus 로고
    • RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice
    • Lapinski PE, Kwon S, Lubeck BA, Wilkinson JE, Srinivasan RS, et al. (2012) RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. J Clin Invest 122: 733-747.
    • (2012) J Clin Invest , vol.122 , pp. 733-747
    • Lapinski, P.E.1    Kwon, S.2    Lubeck, B.A.3    Wilkinson, J.E.4    Srinivasan, R.S.5
  • 36
    • 77950346287 scopus 로고    scopus 로고
    • H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice
    • Ichise T, Yoshida N, Ichise H (2010) H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice. Development 137: 1003-1013.
    • (2010) Development , vol.137 , pp. 1003-1013
    • Ichise, T.1    Yoshida, N.2    Ichise, H.3
  • 37
    • 84874631217 scopus 로고    scopus 로고
    • Endothelial ERK signaling controls lymphatic fate specification
    • Deng Y, Atri D, Eichmann A, Simons M (2013) Endothelial ERK signaling controls lymphatic fate specification. J Clin Invest 123: 1202-1215.
    • (2013) J Clin Invest , vol.123 , pp. 1202-1215
    • Deng, Y.1    Atri, D.2    Eichmann, A.3    Simons, M.4
  • 38
    • 33751252292 scopus 로고    scopus 로고
    • Direct observation of individual endogenous protein complexes in situ by proximity ligation
    • Soderberg O, Gullberg M, Jarvius M, Ridderstrale K, Leuchowius KJ, et al. (2006) Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods 3: 995-1000.
    • (2006) Nat Methods , vol.3 , pp. 995-1000
    • Soderberg, O.1    Gullberg, M.2    Jarvius, M.3    Ridderstrale, K.4    Leuchowius, K.J.5
  • 39
    • 84861851208 scopus 로고    scopus 로고
    • Indocyanine green (ICG) lymphography is superior to lymphoscintigraphy for diagnostic imaging of early lymphedema of the upper limbs
    • Mihara M, Hara H, Araki J, Kikuchi K, Narushima M, et al. (2012) Indocyanine green (ICG) lymphography is superior to lymphoscintigraphy for diagnostic imaging of early lymphedema of the upper limbs. PLoS One 7: e38182.
    • (2012) PLoS One , vol.7 , pp. e38182
    • Mihara, M.1    Hara, H.2    Araki, J.3    Kikuchi, K.4    Narushima, M.5
  • 40
    • 84896765574 scopus 로고    scopus 로고
    • Emerging lymphatic imaging technologies for mouse and man
    • Sevick-Muraca EM, Kwon S, Rasmussen JC (2014) Emerging lymphatic imaging technologies for mouse and man. J Clin Invest 124: 905-914.
    • (2014) J Clin Invest , vol.124 , pp. 905-914
    • Sevick-Muraca, E.M.1    Kwon, S.2    Rasmussen, J.C.3
  • 41
    • 84856541129 scopus 로고    scopus 로고
    • Using indocyanine green fluorescent lymphography and lymphatic-venous anastomosis for cancer-related lymphedema
    • Mihara M, Murai N, Hayashi Y, Hara H, Iida T, et al. (2012) Using indocyanine green fluorescent lymphography and lymphatic-venous anastomosis for cancer-related lymphedema. Ann Vasc Surg 26: 278 e271-276.
    • (2012) Ann Vasc Surg , vol.26 , Issue.278 , pp. e271-e276
    • Mihara, M.1    Murai, N.2    Hayashi, Y.3    Hara, H.4    Iida, T.5
  • 44
    • 0033710778 scopus 로고    scopus 로고
    • The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells
    • Tamir I, Stolpa JC, Helgason CD, Nakamura K, Bruhns P, et al. (2000) The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells. Immunity 12: 347-358.
    • (2000) Immunity , vol.12 , pp. 347-358
    • Tamir, I.1    Stolpa, J.C.2    Helgason, C.D.3    Nakamura, K.4    Bruhns, P.5
  • 45
    • 21044450947 scopus 로고    scopus 로고
    • Impact of SRC homology 2-containing inositol 5′9-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling
    • Kagawa S, Sasaoka T, Yaguchi S, Ishihara H, Tsuneki H, et al. (2005) Impact of SRC homology 2-containing inositol 59-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling. J Clin Endocrinol Metab 90: 2911-2919.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2911-2919
    • Kagawa, S.1    Sasaoka, T.2    Yaguchi, S.3    Ishihara, H.4    Tsuneki, H.5
  • 46
    • 61849110214 scopus 로고    scopus 로고
    • Tec kinases regulate T-lymphocyte development and function: New insights into the roles of Itk and Rlk/Txk
    • Readinger JA, Mueller KL, Venegas AM, Horai R, Schwartzberg PL (2009) Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk. Immunol Rev 228: 93-114.
    • (2009) Immunol Rev , vol.228 , pp. 93-114
    • Readinger, J.A.1    Mueller, K.L.2    Venegas, A.M.3    Horai, R.4    Schwartzberg, P.L.5
  • 47
    • 73649089980 scopus 로고    scopus 로고
    • ERK and cell death: Mechanisms of ERKinduced cell death-apoptosis, autophagy and senescence
    • Cagnol S, Chambard JC (2010) ERK and cell death: mechanisms of ERKinduced cell death-apoptosis, autophagy and senescence. FEBS J 277: 2-21.
    • (2010) Febs J , vol.277 , pp. 2-21
    • Cagnol, S.1    Chambard, J.C.2
  • 48
    • 36048936602 scopus 로고    scopus 로고
    • Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2
    • Moro L, Arbini AA, Marra E, Greco M (2007) Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2. Int J Oncol 30: 217-224.
    • (2007) Int J Oncol , vol.30 , pp. 217-224
    • Moro, L.1    Arbini, A.A.2    Marra, E.3    Greco, M.4
  • 49
    • 84862785325 scopus 로고    scopus 로고
    • Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases
    • Liu X, Ma B, Malik AB, Tang H, Yang T, et al. (2012) Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nat Immunol 13: 457-464.
    • (2012) Nat Immunol , vol.13 , pp. 457-464
    • Liu, X.1    Ma, B.2    Malik, A.B.3    Tang, H.4    Yang, T.5
  • 51
    • 84872323508 scopus 로고    scopus 로고
    • Wholegenome analysis reveals that mutations in inositol polyphosphate phosphataselike 1 cause opsismodysplasia
    • Below JE, Earl DL, Shively KM, McMillin MJ, Smith JD, et al. (2013) Wholegenome analysis reveals that mutations in inositol polyphosphate phosphataselike 1 cause opsismodysplasia. Am J Hum Genet 92: 137-143.
    • (2013) Am J Hum Genet , vol.92 , pp. 137-143
    • Below, J.E.1    Earl, D.L.2    Shively, K.M.3    McMillin, M.J.4    Smith, J.D.5
  • 52
    • 0035804251 scopus 로고    scopus 로고
    • The lipid phosphatase SHIP2 controls insulin sensitivity
    • Clement S, Krause U, Desmedt F, Tanti JF, Behrends J, et al. (2001) The lipid phosphatase SHIP2 controls insulin sensitivity. Nature 409: 92-97.
    • (2001) Nature , vol.409 , pp. 92-97
    • Clement, S.1    Krause, U.2    Desmedt, F.3    Tanti, J.F.4    Behrends, J.5
  • 53
    • 20044364159 scopus 로고    scopus 로고
    • Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
    • Sleeman MW, Wortley KE, Lai KM, Gowen LC, Kintner J, et al. (2005) Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity. Nat Med 11: 199-205.
    • (2005) Nat Med , vol.11 , pp. 199-205
    • Sleeman, M.W.1    Wortley, K.E.2    Lai, K.M.3    Gowen, L.C.4    Kintner, J.5
  • 54
    • 33745727207 scopus 로고    scopus 로고
    • Association of SH-2 containing inositol 5′-phosphatase 2 gene polymorphisms and hyperglycemia
    • Ishida S, Funakoshi A, Miyasaka K, Shimokata H, Ando F, et al. (2006) Association of SH-2 containing inositol 59-phosphatase 2 gene polymorphisms and hyperglycemia. Pancreas 33: 63-67.
    • (2006) Pancreas , vol.33 , pp. 63-67
    • Ishida, S.1    Funakoshi, A.2    Miyasaka, K.3    Shimokata, H.4    Ando, F.5
  • 55
    • 3042820621 scopus 로고    scopus 로고
    • Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome
    • Kaisaki PJ, Delepine M, Woon PY, Sebag-Montefiore L, Wilder SP, et al. (2004) Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome. Diabetes 53: 1900-1904.
    • (2004) Diabetes , vol.53 , pp. 1900-1904
    • Kaisaki, P.J.1    Delepine, M.2    Woon, P.Y.3    Sebag-Montefiore, L.4    Wilder, S.P.5
  • 56
    • 0034701247 scopus 로고    scopus 로고
    • Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis
    • Zhou XP, Marsh DJ, Hampel H, Mulliken JB, Gimm O, et al. (2000) Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis. Hum Mol Genet 9: 765-768.
    • (2000) Hum Mol Genet , vol.9 , pp. 765-768
    • Zhou, X.P.1    Marsh, D.J.2    Hampel, H.3    Mulliken, J.B.4    Gimm, O.5
  • 57
    • 84871326758 scopus 로고    scopus 로고
    • Prospective transcriptomic pathway analysis of human lymphatic vascular insufficiency:Identification and validation of a circulating biomarker panel
    • Lin S, Kim J, Lee MJ, Roche L, Yang NL, et al. (2012) Prospective transcriptomic pathway analysis of human lymphatic vascular insufficiency:identification and validation of a circulating biomarker panel. PLoS One 7:e52021.
    • (2012) Plos One , vol.7 , pp. e52021
    • Lin, S.1    Kim, J.2    Lee, M.J.3    Roche, L.4    Yang, N.L.5
  • 58
    • 0028351702 scopus 로고
    • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
    • Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, et al. (1994) A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77: 261-271.
    • (1994) Cell , vol.77 , pp. 261-271
    • Ponzetto, C.1    Bardelli, A.2    Zhen, Z.3    Maina, F.4    Dalla Zonca, P.5
  • 59
    • 84862637350 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis
    • Coso S, Zeng Y, Opeskin K, Williams ED (2012) Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis. PLoS One 7: e39558.
    • (2012) PLoS One , vol.7 , pp. e39558
    • Coso, S.1    Zeng, Y.2    Opeskin, K.3    Williams, E.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.