Histopathological features of Proteus syndrome

Clinical and Experimental Dermatology

Volumn 33, Issue 3, 2008, Pages 234-238

  Hoey, S E H ^a   Eastwood, D ^a   Monsell, F ^a,b   Kangesu, L ^a   Harper, J I ^a   Sebire, N J ^a  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILD; CLINICAL ARTICLE; CONGENITAL BLOOD VESSEL MALFORMATION; CONTROLLED STUDY; DATA BASE; EDEMA; HAMARTOMA; HEMANGIOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MULTIPLE CANCER; PRIORITY JOURNAL; SKIN DEFECT; SOFT TISSUE;

CHILD; CHILD, PRESCHOOL; CONNECTIVE TISSUE CELLS; FEMALE; GIGANTISM; HEMANGIOMA; HUMANS; INFANT; LIPOMATOSIS; MALE; PHENOTYPE; PROTEUS SYNDROME; SOFT TISSUE NEOPLASMS;

EID: 42249086114     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2007.02601.x     Document Type: Article

References (12)

1. Happle R. Lethal genes surviving by mosaicism: a possible explanation for sporadic birth defects involving the skin. J Am Acad Dermatol 1987 16 : 899 906.
2. Cohen MM, Hayden PW. A newly recognised hamartomatous syndrome. Birth Defects Orig Artic Se 1979 15 : 291 6.
3. Wiedemann HR, Burgio GR, Aldenhoff P et al. The Proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections. Eur J Pediatr 1983 140 : 5 12.
4. Biesecker LG, Happle R, Mulliken JB et al. Proteus syndrome: diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet 1999 84 : 389 95.
5. Hoeger PH, Martinez A, Maerker J, Harper JI. Vascular anomalies in Proteus syndrome. Clin Exp Dermatol 2004 29 : 222 30.
6. Nguyen D, Turner JT, Olsen C et al. Cutaneous manifestations of Proteus syndrome: correlations with general clinical severity. Arch Dermatol 2004 140 : 947 53.
7. Barker K, Martinez A, Wang R et al. PTEN mutations are uncommon in Proteus syndrome. J Med Genet 2001 38 : 480 1.
8. Biesecker LG, Rosenberg MJ, Vacha S et al. PTEN mutations and Proteus syndrome. Lancet 2001 358 : 2079 80.
9. Sampaio C, Martinez A, Barker K et al. Proteus syndrome. In : Textbook of Pediatric Dermatology (Harper JI, Oranje A, Prose N, eds 2nd edn, Vol. 2. Oxford : Blackwell Publishing, 2005 1143 50.
10. Zhou X, Hampel H, Thiele H et al. Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes. Lancet 2001 358 : 210 1.
11. Eng C, Thiele H, Zhou XP et al. PTEN mutations and proteus syndrome. Lancet 2001 358 : 2079 80.
12. Loffeld A, McLellan NJ, Cole T et al. Epidermal naevus in Proteus syndrome showing loss of heterozygosity for an inherited PTEN mutation. Br J Dermatol 2006 154 : 1194 8.