Mutation in vascular endothelial growth factor-c, a ligand for vascular endothelial growth factor receptor-3, is associated with autosomal dominant milroy-like primary lymphedema

Circulation Research

Volumn 112, Issue 6, 2013, Pages 956-960

  Gordon, Kristiana ^a   Schulte, Dörte ^b   Brice, Glen ^c   Simpson, Michael A ^d   Roukens, M Guy ^b   Van Impel, Andreas ^b   Connell, Fiona ^d   Kalidas, Kamini ^a   Jeffery, Steve ^a   Mortimer, Peter S ^a   Mansour, Sahar ^c   Schulte Merker, Stefan ^b,e   Ostergaard, Pia ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^d GUY S HOSPITAL   (United Kingdom)

^e WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

lymphatic capillary; Milroy disease; primary lymphedema; vascular endothelial growth factor; vascular endothelial growth factor receptor

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

ADULT; ANIMAL EXPERIMENT; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; EXOME; FRAMESHIFT MUTATION; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; IN VIVO STUDY; LYMPHEDEMA; LYMPHOSCINTIGRAPHY; MALE; MILROY DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ADOLESCENT; ADULT; ANIMALS; CHILD; FEMALE; FRAMESHIFT MUTATION; HUMANS; LYMPHEDEMA; MALE; PEDIGREE; PHENOTYPE; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3; YOUNG ADULT; ZEBRAFISH;

EID: 84875209848     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.300350     Document Type: Article

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