An in vitro study of the neuroprotective effect of propofol on hypoxic hippocampal slice

Brain Injury

Volumn 28, Issue 13-14, 2014, Pages 1758-1765

  Zhang, Deng Xing ^a   Ding, Hao Zhong ^a   Jiang, Shan ^b   Zeng, Ying Ming ^b   Tang, Qi Feng ^c  

^a JIANGNAN UNIVERSITY   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Hippocampal slice; Hypoxic injury; Neuroprotection; Propofol

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID RECEPTOR AFFECTING AGENT; ASPARTIC ACID; GLUCOSE; GLUTAMIC ACID; GLYCINE; LACTIC ACID; OXYGEN; PROPOFOL; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN EDEMA; BRAIN HYPOXIA; BRAIN PERFUSION; BRAIN SLICE; CELL STRUCTURE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE DURATION; ELECTRON MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIP; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HISTOPATHOLOGY; IN VITRO STUDY; MITOCHONDRION; NERVE CELL LESION; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NICK END LABELING; NONHUMAN; OUTCOME ASSESSMENT; PYRAMIDAL NERVE CELL; RAT; ANIMAL; DRUG EFFECTS; HIPPOCAMPUS; HYPOXIA, BRAIN; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HIPPOCAMPUS; HYPOXIA, BRAIN; IN VITRO TECHNIQUES; NEUROPROTECTIVE AGENTS; PROPOFOL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84911421976     PISSN: 02699052     EISSN: 1362301X     Source Type: Journal    
DOI: 10.3109/02699052.2014.947624     Document Type: Article

References (40)

1. Kataoka K, Yanase H. Mild hypothermia: A revived countermeas-ure against ischemic neuronal damages. Neuroscience Research 1998;32:103-117.
2. Feiner JR, Bickler PE, Estrada S, Donohoe PH, Fahlman CS, Schuyler JA. Mild hypothermia, but not propofol, is neuroprotective in organotypic hippocampal cultures. Anesthesia & Analgesia 2005;100:215-225.
3. Kochs E, Hoffman WE, Werner C, Thomas C, Albrecht RF, Schulte am Esch J. The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats. Anesthesiology 1992;76:245-252.
4. Hara M, Yoshihisa K, Ikemoto Y. Propofol activates GABA (A) receptor chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 1993;79:781-788.
5. Hans P, Bonhomme V, Collette J, Albert A, Moonen G. Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity. Journal of Neurosurgical Anesthesiology 1994;6:249-253.
6. Amorim P, Chambers G, Cottrell J, Kass IS. Propofol reduces neuronal transmission damage and attenuates the changes in calcium, potassium, and sodium during hyperthermic anoxia in the rat hippocampal slice. Anesthesiology 1995;83:1254-1265.
7. Young Y, Menon DK, Tisavipat N, Matta BF, Jones JG. Propofol neuroprotection in a rat model of ischaemia reperfusion injury. European Journal of Anaesthiology 1997;14:320-326.
8. Ito H, Watanabe Y, Isshiki A, Uchino H. Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABA (A) receptors. Acta Anaesthesiologica Scandinavica 1999;43:153-162.
9. Yano T, Nakayama R, Ushijima K. Intracerebroventricular propofol is neuroprotective against transient global ischemia in rats: Extracellular glutamate level is not a major determinant. Brain Research 2000;883:69-76.
10. O'Shea SM, Wong LC, Harrison NL. Propofol increases agonist efficacy at the GABA (A) receptor. Brain Research 2000;85: 344-348.
11. Daskalopoulos R, Korcok J, Farhangkhgoee P, Karmazyn M, Gelb AW, Wilson JX. Propofol protection of sodium-hygrogen exchange activity sustains glutamate uptake during oxidative stress. Anesthesia & Analgesia 2001;93:1199-1204.
12. Grasshoff C, Gillessen T. The effect of propofol on increased superoxide concentration in cultured rat cerebrocortical neurons after stimulation of N-methyl-D-aspartate receptors. Anesthesia & Analgesia 2002;95:920-922.
13. Tsai YC, Huang SJ, Lai YY, Chang CL, Cheng JT. Propofol does not reduce infarc volume in rats undergoing permanent middle cerebral artery occlusion. Acta Anaesthesiologica Sinica 1994;32: 99-104.
14. Kass IS, Schurr A, Teyler TJ, Tseng MT. Brain slices, fundamental, applications and implications. New York: S Karge Publishers Inc; 1986. pp 105-117.
15. Zhang Peilin. Neuroanatomy. Beijing: Beijing People Health Press; 1987.
16. Fairchild MD, Parsons JE, Wasterlain CG, Rinaldi PC, Wallis RA. A hypoxic injury potential in the hippocampal slice. Brain Research 1988;453:357-361.
17. Tokunaga H, Hiramatsu K, Sakaki T Effect of preceding in vivo sublethal ischemia on the evoked potentials during secondary in vitro hypoxia evaluated with gerbil hippocampal slices. Brain Research 1998;784:316-320.
18. Kleckner NW, Dingledine R. Requirement for glycine in activation of NMDA-receptor expressed in xenopus oocytes. Science 1988; 241:835-837.
19. Globus MY, Busto R, Dietnich WD, Ginsberg MD. Comparative effect of transient global ischemia on extracellular levels glutamate, glycine and y-amino butyric acid in vulnerable and nonvulnerable brain regions in the rat. Journal of Neurochemistry 1991;57: 470-478.
20. Kemp JA. The glycine of NMDA receptor-five years on trends. Trends in Pharmacological Sciences 1993;14:20-25.
21. Sitar SM, Hanifi Moghaddam P, Gellb A, Cechetto DF, Siushansian R, Wilson JX. Propofol prevents peroxide-induced inhibition of glutamate transport in cultured asrtocytes. Anesthesiology 1999;91: 1446-1453.
22. Balestrino M, Aitken PG, Somjen GG Spreading depression-like hypoxic depolarization in CA1 and fascia dentate of hippocampal slice: Relationship to selective vulnerability. Brain Research 1989; 497:102-107.
23. Sick TJ, Solow EL, Roberts EL Jr. Extracellular potassium ion activity and electrophysiology in the hippocampal slice: Paradoxical recovery of synaptic transmission during anoxia. Brain Research 1987;418:227-234.
24. 2+-permeable AMPA receptors in neurological disorders. Trends in Neuroscience 1997;20: 464-470.
25. Hirose K, Chan PH. Blockade of glutamate excitoxicity and its clinical applications. Neurochemical Research 1993;18:479-483.
26. Kollegger H, McBean HG, Tipton KF. Reduction of Striatal N-methyl-D-aspartate toxicity by inhibition of nitric oxide syn-thase. Biochemical Pharmacology 1993;45:260-264.
27. Katsura K, Ekholm A, Siesijo BK. Coupling among changes in energy metabolism, acidbase homestasis, and ion fluxes in ischemia. Canadian Journal of Physiology & Pharmacology 1992; 70(Suppl):S170-175.
28. Martins E, Inamura K, Themner K, Malmqvist KG, Siesjö BK. Accumulation of calcium and loss of potassium in the hippocampus following transient cerebral ischemia: A proton microprobe study. Journal of Cerebral Blood Flow & Metabolism 1988;8: 531-538.
29. Salinska E, Pluta R, Puka M, Lazarewicz JW. Blockade of N-methyl-D-aspartate-sensitive excitatory amino acid receptors with 2-amino-5-phosphovalerate reduces ischemia-evoked calcium redistribution in rabbit hippocampus. Experimental Neurology 1991;112:89-94.
30. Xia YX, Zacharias E, Hoff P, Tegtmeier F. Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain. Journal of Cerebral Blood Flow & Metabolism 1995;15:587-594.
31. Rehberg B, Duch DS. Suppression of central nervous system sodium channels by propofol. Anesthesiology 1999;91:512-520.
32. Chen L, Gong Q, Gao H, Xiao C. The effect of propofol, midazolam and sodium thiopental on accumulation of amino acids after reperfusion of ischemic brain in rats. Journal of Chinese Anesthesiology 2001;21:666-668.
33. Lauder JM, Han VKM, Henderson P, Verdoorn T, Towle AC. Prenatal ontogeny of the GABAergic system in the rat brain: an immunocytochemical study. Neuroscience 1986;19:465-493.
34. Fairen CA, Aivarez-Bolado G, Sanchez MP. Prenatal development of intrinsic neurons of rat neocortex: A comparative study of the distribution of GABA-immunoreactive cells and the GABA (A) receptor. Neuroscience 1991;40:375-397.
35. Grondahl TO, Berg-Johnsen J, Langmoen IA. Chloride influx during cerebral energy deprivation. Neurological Research 1998; 20:131-136.
36. Mantz J, Lecharny JB, Laudenbach V, Henzel D, Peytavin G, Desmonts JM. Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes. Anesthesiology 1995;82:502-511.
37. Wang H, Wang G, Wang C, Wei Y, Wen Z, Wang C, Zhu A. The early stage formation of PI3K-AMPAR GluR2 subunit complex facilitates the long term neuroprotection induced by propofol post-conditioning in rats. PLoS One 2013;8:e65187.
38. Cui DR, Wang L, Jiang W, Qi AH, Zhou QH, Zhang XL. Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-kB/p53 signaling pathway. Neuroscience 2013;246:117-132.
39. Shu L, Li T, Han S, Ji F, Pan C, Zhang B, Li J. Inhibition of neuron-specific CREB dephosphorylation is involved in propofol and ketamine-induced neuroprotection against cerebral ischemic injuries of mice. Neurochemical Research 2012;37:49-58.
40. Wang H, Luo M, Li C, Wang G. Propofol post-conditioning induced long-term neuroprotection and reduced internalization of AMPAR GluR2 subunit in a rat model of focal cerebral ischemia/reperfusion. Journal of Neurochemistry 2011;119:210-219.