Pre-emptive value of methylprednisolone intravenous infusion in patients with vertebral metastases. A double-blind randomized study

Journal of Pain and Symptom Management

Volumn 48, Issue 5, 2014, Pages 762-769

  Yousef, Ayman Abd Al Maksoud ^a   El Mashad, Nehal Mohamed ^b  

^a TANTA UNIVERSITY   (Egypt)

^b TANTA UNIVERSITY   (Egypt)

Author keywords

Methylprednisolone; pain flare; vertebral metastasis

Indexed keywords

METHYLPREDNISOLONE; NEUROPROTECTIVE AGENT;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; BRIEF PAIN INVENTORY; DISEASE EXACERBATION; DOUBLE BLIND PROCEDURE; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEGAVOLTAGE RADIOTHERAPY; MOOD CHANGE; MOTOR PERFORMANCE; NUMERICAL RATING SCALE; PAIN; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SPINE METASTASIS; TREATMENT DURATION; CONTROLLED STUDY; DRUG EFFECTS; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; MOTOR ACTIVITY; PAIN MEASUREMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION (PROCESS); SEVERITY OF ILLNESS INDEX; SPINAL NEOPLASMS; TREATMENT OUTCOME;

AGED; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; METHYLPREDNISOLONE; MIDDLE AGED; MOTOR ACTIVITY; NEUROPROTECTIVE AGENTS; PAIN; PAIN MEASUREMENT; SEVERITY OF ILLNESS INDEX; SPINAL NEOPLASMS; TREATMENT OUTCOME;

EID: 84911418038     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2013.12.232     Document Type: Article

References (21)

1. M. Mizumoto, H. Harada, and H. Asakura Prognostic factors and a scoring system for survival after radiotherapy for metastasis to the spinal column Cancer 113 2008 2816 2822
2. O. Zaikova, S.D. Fossa, O.S. Bruland, K.E. Giercksky, and B. Sandstad Radiotherapy or surgery for spine metastases? A population-based study of 903 patients in the south-eastern region of Norway Acta Orthop 82 2011 365 371
3. E. Chow, L. Holden, and J. Rubenstein Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy: a feasibility study Radiother Oncol 70 2004 291 294
4. K.K. Li, S. Hadi, A. Kirou-Mauro, and E. Chow When should we define the response rates in the treatment of bone metastases by palliative radiotherapy? Clin Oncol (R Coll Radiol) 20 2008 83 89
5. D.A. Loblaw, J.S.Y. Wu, and P. Warde Pain flare in patients with bone metastases after palliative radiotherapy: a nested randomized controlled trial Support Care Cancer 15 2007 451 455
6. A. Hird, L. Zhang, and T. Holt Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for symptomatic bone metastases: a phase II study Clin Oncol 21 2009 329 335
7. D. Rades, T. Veninga, and L.J. Stalpers Outcome after radiotherapy alone for metastatic spinal cord compression in patients with oligometastases J Clin Oncol 25 2007 50 56
8. E. Chow, D.A. Loblaw, and K. Harris Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study Support Care Cancer 15 2007 643 664
9. H. Hugenholtz, D.E. Cass, and M.F. Dvorak High-dose methylprednisolone for acute closed spinal cord injury - only a treatment option Can J Neurol Sci 29 2002 227 235
10. S.P. Kumar Utilization of brief pain inventory as an assessment tool for pain in patients with cancer. A focused review Indian J Palliat Care 17 2011 108 115
11. K. San, M.B. Carla, and L.D. Sheri Validity of the Brief Pain Inventory for use in documenting the outcomes of patients with noncancer pain Clin J Pain 20 2004 309 318
12. K.A.S.L. Ferreira, M. Kimura, and M.J. Teixeira The WHO analgesic ladder for cancer pain control, twenty years of use. How much pain relief does one get from using it? Support Care Cancer 14 2006 1086 1093
13. D. Rades, L.J.A. Stalpers, and T. Veninga Evaluation of five radiation schedules and prognostic factors for metastatic spinal cord compression J Clin Oncol 23 2005 3366 3375
14. S.I. Grivennikov, F.R. Greten, and M. Karin Immunity, inflammation and cancer Cell 140 2010 883 899
15. A. Hird, E. Chow, and L. Zhang Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases. Results from three Canadian cancer centers Int J Radiat Oncol Biol Phys 75 2009 193 197
16. E. Chow, A. Ling, L. Davis, T. Panzarella, and C. Danjoux Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastases Radiother Oncol 75 2005 64 69
17. K. Takda, S. Sawamura, H. Sekiyama, H. Tamai, and K. Hanaoka Effect of methylprednisolone on neuropathic pain and spinal glial activation in rats Anesthesiology 100 2004 1249 1257
18. T.C. Griffin, D. McIntire, and G.R. Buchanan High-dose intravenous methylprednisolone therapy for pain in children and adolescents with sickle cell disease N Engl J Med 330 1994 733 737
19. E.D. Hall, and J.E. Springer Neuroprotection and acute spinal cord injury: a reappraisal NeuroRx 1 2004 80 100
20. M.B. Bracken, M.J. Shepard, and W.F. Collins A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury N Engl J Med 322 1990 1405 1411
21. P.S. Sorensen, S. Helweg-Larsen, and H. Mouridsen Effects of high-dose dexamethasone in carcinamatous metastatic spinal cord compression treated with radiotherapy: a randomized trial Eur J Cancer 30A 1994 22 27.