Modeling of plant in vitro cultures: Overview and estimation of biotechnological processes

Biotechnology and Bioengineering

Volumn 112, Issue 1, 2015, Pages 1-12

  Maschke, Rüdiger W ^a   Geipel, Katja ^a   Bley, Thomas ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Cell suspension culture; Hairy root; Kinetic model; Mathematical model; Plant biotechnology; Simulation

Indexed keywords

BIOTECHNOLOGY; CELL CULTURE; CULTIVATION; MATHEMATICAL MODELS;

CELL SUSPENSION CULTURES; HAIRY ROOTS; KINETIC MODELING; PLANT BIOTECHNOLOGY; SIMULATION;

COMPUTER SIMULATION;

CELL GROWTH; CHRONOLOGY; HAIRY ROOT CULTURE; IN VITRO STUDY; MATHEMATICAL MODEL; NONHUMAN; PLANT BIOTECHNOLOGY; PLANT CELL; PLANT CELL CULTURE; PLANT PARAMETERS; PREDICTION; REVIEW; SUSPENSION CELL CULTURE; BIOLOGICAL MODEL; BIOTECHNOLOGY; EMBRYOLOGY; KINETICS; METABOLISM; PLANT; PROCEDURES; TISSUE CULTURE TECHNIQUE;

BIOTECHNOLOGY; KINETICS; MODELS, BIOLOGICAL; PLANT CELLS; PLANTS; TISSUE CULTURE TECHNIQUES;

EID: 84911366683     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25346     Document Type: Review

References (75)

1. Allen MP, Tildesley DJ. 1989. Computer simulation of liquids. Oxford University Press.
2. Bailey CM, Nicholson H. 1989. A new structured model for plant cell culture. Biotechnol Bioeng 34:1331-1336.
3. Bailey CM, Nicholson H. 1990. Optimal temperature control for a structured model of plant cell culture. Biotechnol Bioeng 35:252-259.
4. Bailey CM, Nicholson H, Morris P, Smart NJ. 1985. A simple model of growth and product formation in cell suspensions of Catharanthus roseus G. Don Appl Biochem Biotechnol 11:207-219.
5. Bailey JE. 1998. Mathematical modeling and analysis in biochemical engineering: Past accomplishments and future opportunities. Biotechnol Prog 14:8-20.
6. Bastian P, Chavarría-Krauser A, Engwer C, Jäger W, Marnach S, Ptashnyk M. 2008. Modelling in vitro growth of dense root networks. J Theor Biol 254:99-109.
7. Becker T, Krause D. 2010. Softsensorsysteme-Mathematik als Bindeglied zum Prozessgeschehen. Chem Ing Tech 82:429-440.
8. Bley T. 2011. From single cells to microbial population dynamics: Modelling in biotechnology based on measurements of individual cells. Adv Biochem Eng Biotechnol 124:211-227.
9. Bramble JL, Graves DJ, Brodelius P. 1991. Calcium and phosphate effects on growth and alkaloid production in Coffea arabica: Experimental results and mathematical model. Biotechnol Bioeng 37:859-868.
10. Choi J-W, Kim Y-K, Lee WH, Pedersen H, Chin C-K. 1999. Kinetic model of cell growth and secondary metabolite synthesis in plant cell culture of Thalictrum rugosum. Biotechnol Bioprocess Eng 4:129-137.
11. Cloutier M, Bouchard-Marchand É, Perrier M, Jolicoeur M. 2008. A predictive nutritional model for plant cells and hairy roots. Biotechnol Bioeng 99:189-200.
12. Curtis WR, Hasegawa PM, Emery AH. 1991. Modeling linear and variable growth in phosphate limited suspension cultures of Opium poppy. Biotechnol Bioeng 38:371-379.
13. de Gunst MCM, Harkes PAA, Val J, van Zwet WR, Libbenga KR. 1990. Modelling the growth of a batch culture of plant cells: A corpuscular approach. Enzyme Microb Technol 12:61-71.
14. Doran PM. 2009. Bioreactors, stirred tank for culture of plant cells. In: Flickinger MC, editor. Encyclopedia of industrial biotechnology, bioprocess, bioseparation, and cell technology. John Wiley & Sons, Inc.
15. Dörnenburg H, Knorr D. 1995. Strategies for the improvement of secondary metabolite production in plant cell cultures. Enzyme Microb Technol 17:674-684.
16. Dunn IJ, Heinzle E, Ingham J, Prenosil JE. 2003. Biological reaction engineering: Dynamic modelling fundamentals with simulation examples. 2nd edition. Weinheim: Wiley-VCH. p 524.
17. Eibl R, Eibl D. 2008. Design of bioreactors suitable for plant cell and tissue cultures. Phytochem Rev 7:593-598.
18. Frazier GC. 1989. A simple, leaky cell growth model for plant cell aggregates. Biotechnol Bioeng 33:313-320.
19. Fredrickson AG, Ramkrishna D, Tsuchiya HM. 1967. Statistics and dynamics of procaryotic cell populations. Math Biosci 1:327-374.
20. Gaden EL. 1959. Fermentation process kinetics. J Biochem Microbiol Technol Eng 1:413-429.
21. Geipel K, Socher ML, Haas C, Bley T, Steingroewer J. 2013. Growth kinetics of a Helianthus annuus and a Salvia fruticosa suspension cell line: Shake flask cultivations with online monitoring system. Eng Life Sci 13:593-602.
22. Geipel K, Song X, Socher M, Kümmritz S, Püschel J, Bley T, Ludwig-Müller J, Steingroewer J. 2014. Induction of a photomixotrophic plant cell culture of Helianthus annuus and optimization of culture conditions for improved α-tocopherol production. Appl Microbiol Biotechnol 98:2029-2040.
23. Georgiev M, Pavlov A, Bley T. 2007. Hairy root type plant in vitro systems as sources of bioactive substances. Appl Microbiol Biotechnol 74:1175-1185.
24. Georgiev M, Weber J, Maciuk A. 2009. Bioprocessing of plant cell cultures for mass production of targeted compounds. Appl Microbiol Biotechnol 83:809-823.
25. Georgiev M, Eibl R, Zhong J-J. 2013. Hosting the plant cells in vitro: Recent trends in bioreactors. Appl Microbiol Biotechnol 97:3787-3800.
26. Glicklis R, Mills D, Sitton D, Stortelder W, Merchuk JC. 1998. Polysaccharide production by plant cells in suspension: Experiments and mathematical modeling. Biotechnol Bioeng 57:732-740.
27. Guardiola J, Iborra JL, Canovas M. 1995. A model that links growth and secondary metabolite production in plant cell suspension cultures. Biotechnol Bioeng 46:291-297.
28. Haas C, Weber J, Ludwig-Muller J, Deponte S, Bley T, Georgiev M. 2008. Flow cytometry and phytochemical analysis of a sunflower cell suspension culture in a 5-L bioreactor. Z für Naturforschung C J Biosci 63:699-705.
29. Han B, Linden JC, Gujarathi NP, Wickramasinghe SR. 2004. Population balance approach to modeling hairy root growth. Biotechnol Prog 20:872-879.
30. Haseltine EL, Rawlings JB. 2005. Critical evaluation of extended Kalman filtering and moving-horizon estimation. Ind Eng Chem Res 44:2451-2460.
31. Hepler PK, Wayne RO. 1985. Calcium and plant development. Annu Rev Plant Physiol 36:397-439.
32. Hjortso MA. 1997. Mathematical modelling of hairy root growth. In: Doran PM, editor. Hairy roots: Culture and application. Harwood Academic Publishers. Amsterdam, The Netherlands: p 169-178.
33. Hooker BS, Lee JM. 1992. Application of a new structured model to tobacco cell cultures. Biotechnol Bioeng 39:765-774.
34. Jolicoeur M, Bouchard-Marchand E, Bécard G, Perrier M. 2002. Regulation of mycorrhizal symbiosis: Development of a structured nutritional dual model. Ecol Model 158:121-142.
35. Kalman RE. 1960. A new approach to linear filtering and prediction problems. J Basic Eng 82:35-45.
36. Kieran PM. 2001. Bioreactor design for plant cell suspension cultures. New Jersey: Harwood Academic.
37. King RE, Aragona J, Constantinides A. 1974. Specific optimal control of a batch fermentor. Int J Control 20:869-879.
38. Knobloch K-H, Beutnagel G, Berlin J. 1981. Influence of accumulated phosphate on culture growth and formation of cinnamoyl putrescines in medium-induced cell suspension cultures of Nicotiana tabacum. Planta 153:582-585.
39. Kolewe ME, Gaurav V, Roberts SC. 2008. Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Mol Pharm 5:243-256.
40. Kolewe ME, Henson MA, Roberts SC. 2011. Analysis of aggregate size as a process variable affecting paclitaxel accumulation in Taxus suspension cultures. Biotechnol Prog 27:1365-1372.
41. Kolewe ME, Roberts SC, Henson MA. 2012. A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnol Bioeng 109:472-482.
42. Kottmeier K, Weber J, Müller C, Bley T, Büchs J. 2009. Asymmetric division of Hansenula polymorpha reflected by a drop of light scatter intensity measured in batch microtiter plate cultivations at phosphate limitation. Biotechnol Bioeng 104:554-561.
43. Krull R, Wucherpfennig T, Esfandabadi ME, Walisko R, Melzer G, Hempel DC, Kampen I, Kwade A, Wittmann C. 2013. Characterization and control of fungal morphology for improved production performance in biotechnology. J Biotechnol 163:112-123.
44. Leduc M, Tikhomiroff C, Cloutier M, Perrier M, Jolicoeur M. 2006. Development of a kinetic metabolic model: Application to Catharanthus roseus hairy root. Bioprocess Biosyst Eng 28:295-313.
45. Lee JM. 1992. Biochemical engineering. Englewood Cliffs, NJ: Prentice Hall X. p 321.
46. Lenk F, Sürmann A, Oberthür P, Schneider M, Steingroewer J, Bley T. 2014. Modeling hairy root tissue growth in in vitro environments using an agent-based, structured growth model. Bioprocess Biosyst Eng 37:1173-1184.
47. Li C, Yuan Y-J, Wu J-C, Hu Z-D. 2003. A structured kinetic model for suspension cultures of Taxus chinensis var. mairei induced by an oligosaccharide from Fusarium oxysporum. Biotechnol Lett 25:1335-1343.
48. Luedeking R, Piret EL. 1959. Transient and steady states in continuous fermentation. Theory and experiment. J Biochem Microbiol Technol Eng 1:431-459.
49. Mairet F, Villon P, Boitel-Conti M, Shakourzadeh K. 2010. Modeling and optimization of hairy root growth in fed-batch process. Biotechnol Prog 26:847-856.
50. Monod J. 1959. Recherche sur la croissance des cultures bactériennes. Hermann: Actualités Scientifiques et Industrielles.
51. Mulabagal V, Tsay H-S. 2004. Plant cell cultures-An alternative and efficient source for the production of biologically important secondary metabolites. Int J Appl Sci Eng 2(1):29-48.
52. Müller S, Bley T. 2010. Flow cytometry. In: Flickinger MC, Drew S, editors. Encyclopedia of industrial biotechnology, bioprocess, bioseparation, and cell technology. Vol. 7. New York: Wiley. p 2451-2467.
53. Murashige T, Skoog F. 1962. A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physiol Plant 15:473-497.
54. Mustafa NR, de Winter W, van Iren F, Verpoorte R. 2011. Initiation, growth and cryopreservation of plant cell suspension cultures. Nat Protoc 6:715-742.
55. Nakashimada Y, Uozumi N, Kobayashi T. 1994. Stimulation of emergence of root apical meristems in horseradish hairy root by auxin supplementation and its kinetic model. J Ferment Bioeng 77:178-182.
56. Omar R, Abdullah MA, Hasan MA, Rosfarizan M, Marziah M. 2006. Kinetics and modelling of cell growth and substrate uptake in Centella asiatica cell culture. Biotechnol Bioprocess Eng 11:223-229.
57. Palavalli RR, Srivastava S, Srivastava AK. 2012. Development of a mathematical model for growth and oxygen transfer in in vitro plant hairy root cultivations. Appl Biochem Biotechnol 167:1831-1844.
58. Pires Cabral PMNAC, Lima Costa ME, Cabral JMS. 2000. A structured growth model for Cynara cardunculus cell suspension. Bioprocess Eng 23:199-203.
59. Rao SR, Ravishankar GA. 2002. Plant cell cultures: Chemical factories of secondary metabolites. Biotechnol Adv 20:101-153.
60. Sagmeister P, Wechselberger P, Jazini M, Meitz A, Langemann T, Herwig C. 2013. Soft sensor assisted dynamic bioprocess control: Efficient tools for bioprocess development. Chem Eng Sci 96:190-198.
61. Schlatmann JE, Koolhaas CMA, Vinke JL, tenHoopen HJG, Heijnen JJ. 1995a. The role of glucose in ajmalicine production by Catharanthus roseus cell cultures. Biotechnol Bioeng 47:525-534.
62. Schlatmann JE, Moreno PRH, Vinke JL, Ten Hoopen HJG, Verpoorte R, Heijnen JJ. 1997. Gaseous metabolites and the ajmalicine production rate in high density cell cultures of Catharanthus roseus. Enzyme Microb Technol 20:107-115.
63. Schlatmann JE, TenHoopen HJG, Heijnen JJ. 1999. A simple structured model for maintenance, biomass formation, and ajmalicine production by nondividing Catharanthus roseus cells. Biotechnol Bioeng 66:147-157.
64. Schlatmann JE, Vinke JL, tenHoopen HJG, Heijnen JJ. 1995b. Relation between dissolved oxygen concentration and ajmalicine production rate in high-density cultures of Catharanthus roseus. Biotechnol Bioeng 45:435-439.
65. Schügerl K. 2001. Progress in monitoring, modeling and control of bioprocesses during the last 20 years. J Biotechnol 85:149-173.
66. Shibasaki N, Yonemoto T, Tadaki T. 1993. Application of five-state structured models for growth and secondary metabolite production in cultures of Nicotiana tabacum. J Chem Technol Biotechnol 58:151-157.
67. Sirois J, Perrier M, Archambault J. 2000. Development of a two-step segregated model for the optimization of plant cell growth. Control Eng Pract 8:813-820.
68. Smetanska I. 2008. Production of secondary metabolites using plant cell cultures. In: Stahl U, Donalies UB, Nevoigt E, editors. Food biotechnology. Berlin Heidelberg: Springer. p 187-228.
69. Takeda T, Takeuchi Y, Seki M, Furusaki S, Matsuoka H. 1998. Kinetic analysis of cell growth and vitamin E production in plant cell culture of Carthamus tinctorius using a structured model. Biochem Eng J 1:233-242.
70. Taya M, Kino-oka M, Tone S, Kobayashi T. 1989. A kinetic model of branching growth of plant hairy root. J Chem Eng Jpn 22:698-700.
71. Uozumi N, Makino S, Kobayashi T. 1995. 20-Hydroxyecdysone production in Ajuga hairy root controlling intracellular phosphate content based on kinetic model. J Ferment Bioeng 80:362-368.
72. van Gulik WM, TenHoopen HJ, Heijnen JJ. 1993. A structured model describing carbon and phosphate limited growth of Catharanthus roseus plant cell suspensions in batch and chemostat culture. Biotechnol Bioeng 41:771-780.
73. Weathers P, Towler M, Xu J. 2010. Bench to batch: Advances in plant cell culture for producing useful products. Appl Microbiol Biotechnol 85:1339-1351.
74. Yan Q, Wu J, Liu R. 2011. Modeling of tanshinone synthesis and phase distribution under the combined effect of elicitation and in situ adsorption in Salvia miltiorrhiza hairy root cultures. Biotechnol Lett 33:813-819.
75. Zhang J, Su WW. 2002. Estimation of intracellular phosphate content in plant cell cultures using an extended Kalman filter. J Biosci Bioeng 94:8-14.