Cancer stem cells and stemness markers in oral squamous cell carcinomas

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 20, 2014, Pages 8549-8556

  Patel, Shanaya Saurin ^a   Shah, Kanisha Atul ^a   Shah, Manoj Jashwantbhai ^a   Kothari, Kiran Champaklal ^a   Rawal, Rakesh Mahesh ^a  

^a GUJARAT CANCER AND RESEARCH INSTITUTE   (India)

Author keywords

Cancer stem cells; Oral squamous cell carcinoma; Self renewal and proliferation; Stemness markers

Indexed keywords

TUMOR MARKER;

CANCER STEM CELL; CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION; FEMALE; HEAD AND NECK NEOPLASMS; HUMAN; MALE; MORTALITY; MOUTH NEOPLASMS; PATHOLOGY; RISK ASSESSMENT; SURVIVAL; TUMOR RECURRENCE;

CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MOUTH NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; NEOPLASTIC STEM CELLS; RISK ASSESSMENT; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84911162812     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.20.8549     Document Type: Short Survey

References (85)

1. Albert S, Hourseau M, Halimi C, et al, (2012). Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue. Oral Oncol, 48, 1263-71.
2. Al-Hajj M, Wicha MS, Benito-Hernandez A (2003). Prospective identification of tumourigenic breast cancer cells. ProcNatlAcadSci USA, 100, 3983-8.
3. Bankovic J, Stojsic J, Jovanovic D, et al, (2010). Identification of genes associated with non-small-cell lung cancer promotion and progression. Lung Cancer, 67, 151-9.
4. Bass AJ, Watanabe H, Mermel CH, et al, (2009). SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics, 41, 1238-42.
5. Boldrup L, Coates PJ, Gu X, Nylander K. (2007). Delta Np63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck. J Pathol, 4, 384-391.
6. Bonner JA, Harari PM, Giralt J, et al, (2006). Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med, 354, 567-78.
7. Bonnet D, Dick JE (1997). Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med, 3, 730-7.
8. Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T (2005). Migrating cancer stem cells-an integrated concept of malignant tumour progression. Nature Reviews Cancer, 5, 744-9.
9. Campoli M, Ferrone S, Wang X (2010). Functional and clinical relevance of chondroitin sulfate proteoglycan 4. Adv Cancer Res, 109, 73-121.
10. Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP (2005). Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer, 114, 806-16.
11. Chen YC, Chen YW, Hsu HS, et al, (2009). Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer. Biochem Biophys Res Commun, 385, 307-13.
12. Chen YW, Chen KH, Huang PI, et al, (2010). Cucurbitacin I Suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44+ALDH+ cells. Mol Cancer Ther, 9, 2879-92.
13. Chen Z (2009). The cancer stem cell concept in progression of head and neck cancer. J Oncol, 2009, 894064.
14. Chen H, Zhou L, Dou T, et al, (2011). Bmi-1's maintenance of the proliferative capacity of laryngeal cancer stem cells. Head Neck, 33, 1115-25.
15. Chikamatsu K, Ishii H, Takahashi G, et al, (2011). Resistance to apoptosis-inducing stimuli in CD44+ head and neck squamous cell carcinoma cells. Head Neck, 34, 336-343.
16. Chikamatsu K, Takahashi G, Sakakura K, Ferrone S, Masuyama K. (2011). Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck. Head Neck, 33, 208-15.
17. Chiou SH, Yu CC, Huang CY, et al, (2008). Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high grade oral squamous cell carcinoma. Clin Cancer Res, 14, 4085-95.
18. Chiou SH, Yu CC, Lo WL, et al, (2011). Bmi-1 regulates snail expression and promotes metastasis ability in head and neck squamous cancer-derived ALDH1 positive cells. J Oncol, 609259
19. Clay MR, Tabor M, Owen JH, et al, (2010). Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck, 32, 1195-201.
20. Davis SJ, Divi V, Owen JH, et al, (2010). Metastatic potential of cancer stem cells in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg, 136, 1260-6.
21. Facompre N, Nakagawa H, Herlyn M, Basu D (2012). Stem-like cells and therapy resistance in squamous cell carcinomas. AdvPharmacol, 65, 235-265.
22. Gao Q, Tong W, Luria JS, et al, (2010). Effects of bone morphogenetic protein-2 on proliferation and angiogenesis in oral squamous cell carcinoma. Int J Oral Maxillofac Surg, 39, 266-71.
23. Geng S, Guo Y, Wang Q, Li L, Wang J (2013). Cancer stem-like cells enriched with CD29 and CD44 markers exhibit molecular characteristics with epithelial-mesenchymal transition in squamous cell carcinoma. Arch Dermatol Res, 305, 35-47.
24. Ginestier C, Hur MH, Charafe-Jauffret E, et al, (2007). ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell, 1, 555-67.
25. Grimm M, Krimmel M, Polligkeit J, et al, (2012). ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma. Eur J Cancer, 48, 3186-97.
26. Haegebarth A, Clevers H (2009). Wnt signaling, Lgr5, and stem cells in the intestine and skin. Am J Pathol, 174, 715-21.
27. Hombach-Klonisch S, Paranjothy T, Wiechec E, et al, (2008). Cancer stem cells as targets for cancer therapy: selected cancers as examples. Arch ImmunolTherExp (Warsz), 56, 165-80.
28. Huang C, Zhu Y, Duan GL, et al, (2013). Screening for MiRNAs related to laryngeal squamous carcinoma stem cell radiation. Asian Pac J Cancer Prev, 14, 4533-7.
29. Jeng JH, Wang YJ, Chiang BL, et al, (2003). Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-α production of oral epithelial cells by areca nut extract and arecoline. Carcinogenesis, 24, 1301-15.
30. Kejner AE, Burch MB, Sweeny L, Rosenthal EL (2013). Bone morphogenetic protein 6 expression in oral cavity squamous cell cancer is associated with bone invasion. Laryngoscope, 123, 3061-5.
31. Keymoosi H, Gheytanchi E, Asgari M, Shariftabrizi A, Madjd Z (2014). ALDH1 in Combination with CD44 as putative cancer stem cell markers are correlated with poor prognosis in urothelial carcinoma of the urinary bladder. Asian Pac J Cancer Prev, 15, 2013-20.
32. Lapidot T, Sirard C, Vormoor J, et al, (1994). A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature, 367, 645-8.
33. Lim YC, Oh SY, Cha YY, et al, (2011). Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas. Oral Oncol, 47, 83-91.
34. Liu W, Feng JQ, Shen XM, et al, (2012). Two stem cell markers, ATP-binding cassette, G2 subfamily (ABCG2) and BMI-1, predict the transformation of oral leukoplakia to cancer: a long-term follow-up study. Cancer, 118, 1693-700.
35. Lu SL, Herrington H and Wang XJ (2006). Mouse models for human head and neck squamous cell carcinomas. Head Neck, 28, 945-54.
36. Madhira SL, Vemuganti G, Bhaduri A, et al, (2008). Culture and characterization of oral mucosal epithelial cells on human amniotic membrane for ocular surface reconstruction. Mol Vis, 14, 189-96.
37. Madjd Z, Ramezani B, Molanae S, Asadi-Lari M (2012). High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas. Asian Pac J Cancer Prev, 13, 2973-8.
38. Maetzel D, Denzel S, Mack B, et al, (2009). Nuclear signalling by tumour-associated antigen EpCAM. Nat. Cell Biol, 11, 162-71.
39. Major AG, Pitty LP, Farah CS (2013). Cancer stem cell markers in head and neck squamous cell carcinoma. Stem Cells International, 319489.
40. Mao L, Hong WK, Papadimitrakopoulou VA (2004). Focus on head and neck cancer. Cancer Cell, 5, 311-6.
41. Mascolo M, GennaroIlardi, Romano MF (2012). Overexpression of chromatin assembly factor-1 p60, poly(ADP-ribose) polymerase 1 and nestin predicts metastasizing behaviour of oral cancer. Histopathology, 61, 1089-105.
42. McCullough MJ, Prasad G, Farah CS (2010). Oral mucosal malignancy and potentially malignant lesions: an update on the epidemiology, risk factors, diagnosis and management. Aust Dent J, 55, 61-65.
43. Meng X, Wuyi L, Yuhong X, Xinming C (2010). Expression of CXCR4 in oral squamous cell carcinoma: correlations with clinicopathology and pivotal role of proliferation. J Oral Pathol Med, 39, 63-8.
44. Mishra A, Verma M (2010). Cancer biomarkers: are we ready for the prime time? Cancers, 2, 190-208.
45. Moral M, Segrelles C, Belén A, et al, (2009). Transgenic mice expressing constitutively active akt in oral epithelium validate Klf4 as a potential biomarker of head and neck squamous cell carcinoma. In Vivo, 23, 653-660.
46. Normanno N, De Luca A, Maiello MR, et al, (2004). CRIPTO-1: a novel target for therapeutic intervention in human carcinoma. Int J Oncol, 25, 1013-20.
47. National Cancer Registry Report 2008
48. Nübel T, Preobraschenski J, Tuncay H, et al, (2009). Claudin-7 regulates EpCAM-mediated functions in tumour progression. Mol. Cancer Res, 7, 285-99.
49. Prince ME, Sivanandan R, Kaczorowski A, et al, (2007). Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. ProcNatlAcadSci USA, 104, 973-8.
50. Prince ME, Ailles LE (2008). Cancer stem cells in head and neck squamous cell cancer. J Clin Oncol, 26, 2871-5.
51. Poage GM, Christensen BC, Houseman EA, et al, (2010) Genetic and epigenetic somatic alterations in head and neck squamous cell carcinomas are globally coordinated but not locally targeted. PLoS ONE, 5, 9651.
52. Qiao B, Johnson NW, Chen X et al, (2011). Disclosure of a stem cell phenotype in an oral squamous cell carcinoma cell line induced by BMP-4 via an epithelial-mesenchymal transition. Oncol Rep, 26, 455-61.
53. Qiao B, Gopalan V, Chen Z et al, (2012). Epithelial mesenchymal transition and mesenchymal epithelial transition are essential for the acquisition of stem cell properties in hTERT- immortalised oral epithelial cells. Biol Cell, 8, 476-89.
54. Qiao B, Chen Z, Hu F, Tao Q, Lam AK. (2013). BMI-1 activation is crucial in hTERT- induced epithelial-mesenchymal transition of oral epithelial cells. Exp Mol Pathol, 1, 57-61.
55. Radisky DC, LaBarge MA (2008). Epithelial-mesenchymal transition and the stem cell phenotype. Cell Stem Cell, 2, 511-2.
56. Ravindran G, Devaraj H (2012). Aberrant expression of CD133 and musashi-1 in pre-neoplastic and neoplastic human oral squamous epithelium and their correlation with clinicopathological factors. Head Neck, 34, 1129-35.
57. Satpute PS, Hazarey V, Ahmed R, Yadav L (2013). Cancer stem cells in head and neck squamous cell carcinoma: a review. Asian Pac J Cancer Prev, 14, 5579-87
58. Scully C, Bagan J (2009). Oral squamous cell carcinoma overview. Oral Oncology, 45, 301-308.
59. Sen S, Sharma S, Gupta A, et al, (2011). Molecular characterization of explant cultured human oral mucosal epithelial cells. Invest Ophthalmol Vis Sci, 52, 9548-9554.
60. Shimada Y, Ishii G, Nagai K, et al, (2009). Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lung. Cancer Sci, 100, 2054-2059.
61. Shmelkov SV, Butler JM, Hooper AT, et al, (2008). CD133 expression is not restricted to stem cells and both CD133+ and CD133- metastatic colon cancer cells initiate tumours. J Clin Invest, 118, 2111-20.
62. Siu A, Lee C, Dang D, Lee C, Ramos DM (2012). Stem cell markers as predictors of oral cancer invasion. Anticancer Res, 32, 1163-6.
63. Sterz CM, Kulle C, Dakic B, et al, (2010). A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the tumour and is expressing MMP-9. Oral Oncol, 46, 116-22.
64. Sun S, Wang Z (2011). Head neck squamous cell carcinoma c- Met+ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis. Int J Cancer, 129, 2337-48.
65. Sun Y, Han J, Lu Y, Yang X, Fan M (2012). Biological characteristics of a cell subpopulation in tongue squamous cell carcinoma. Oral Diseases, 18, 169-177.
66. Tabor MH, Clay MR, Owen JH et al, (2011). Head and neck cancer stem cells: the side population. Laryngoscope, 121, 527-33.
67. Tsai LL, Yu CC, and Chang YC, (2011). Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma. J Oral Pathol Med, 40, 621-8.
68. Vaiphei K, Sinha SK, Kochhar R (2014). Comparative analysis of Oct4 in different histological subtypes of esophageal squamous cell carcinomas in different clinical conditions. Asian Pac J Cancer Prev, 15, 3519-24.
69. Van der Gun BT, Melchers LJ, Ruiters MH, et al, (2010). EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis, 31, 1913-21.
70. Visvader JE and Lindeman GJ (2008). Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature Reviews Cancer, 8, 755-68.
71. Von Rahden BHA, Kircher S, Lazariotou M, et al, (2011). LgR5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett's Esophagus?. J Exp Clin Cancer Res, 30, 23.
72. Vincent-Chong VK, Ismail SM, Rahman ZA, et al, (2012). Genome-wide analysis of oral squamous cell carcinomas revealed over expression of ISG15, Nestin and WNT11. Oral Dis, 18, 469-76.
73. Winter MJ, Nagelkerken B, Mertens AE, et al, (2003). Expression of Ep-CAM shifts the state of cadherin-mediated adhesions from strong to weak. Exp. Cell Res, 285, 50-8.
74. Warnakulasuriya S (2009). Global epidemiology of oral and oropharyngeal cancer. Oral Oncol, 45, 309-16.
75. Wang X, Wang Y, Yu L, et al, (2010). CSPG4 in cancer: multiple roles. Curr Mol Med, 10, 419-29.
76. Wu MJ, Jan CI, Tsay YG, et al, (2010). Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling. Molecular Cancer, 9, 283.
77. Wu Y, Wu PY (2009). CD133 as a marker for cancer stem cells: progresses and concerns. Stem Cells Dev, 18, 1127-34.
78. Yamamoto Y, Sakamoto M, Fujii G, et al, (2003). Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with b-catenin mutations. Hepatol, 37, 528-33.
79. Yan M, Yang X, Wang L, et al, (2013). Plasma membrane proteomics of tumour spheres identify CD166 as a novel marker for cancer stem-like cells in head and neck squamous cell carcinoma. Mol Cell Proteomics, 12, 3271-84.
80. Yarnazaki H, Mori T, Yazawa M, et al, (2013). Stem cell self-renewal factors Bmi-1 and HMGA2 in head and neck squamous cell carcinoma: clues for diagnosis. Laboratory Investigations, 93, 1331-8.
81. Yoon HJ, Hong JS, Shin WJ, et al, (2011). The role of Cripto-1 in the tumourigenesis and progression of oral squamous cell carcinoma. Oral Oncol, 47, 1023-31.
82. Yu Q, Toole BP, Stamenkovic I (1997). Induction of apoptosis of metastatic mammary carcinoma cells invivo by disruption of tumour cell surface CD44 function. J Exp Med, 186, 1985-96.
83. Yu Q, Stamenkovic I (1999). Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44- mediated tumour invasion. Genes Deve, 13, 35-48.
84. Zhang P, Zhang Y, Mao L, Zhang Z, Chen W (2009). Side population in oral squamous cell carcinoma possesses tumour stem cell phenotypes. Cancer Lett, 277, 227-334.
85. Zhang Q, Shi S, Yen Y, et al, (2010). A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy. Cancer Lett, 289, 151-60.