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Volumn 32, Issue 11, 2014, Pages 1055-1061

Through a Glass Darkly: Economics and Personalised Medicine

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 84911006269     PISSN: 11707690     EISSN: 11792027     Source Type: Journal    
DOI: 10.1007/s40273-014-0190-6     Document Type: Article
Times cited : (18)

References (25)
  • 1
    • 79961113774 scopus 로고    scopus 로고
    • Health technology assessment in the era of personalized medicine
    • Becla L, Lunshof J, Gurwitz D, et al. Health technology assessment in the era of personalized medicine. Int Jn Tech Ass Health Care. 2011;27:118–26
    • (2011) Int Jn Tech Ass Health Care , vol.27 , pp. 118-126
    • Becla, L.1    Lunshof, J.2    Gurwitz, D.3
  • 2
    • 84866593873 scopus 로고    scopus 로고
    • Pharmacogenomics and individualized medicine: translating science into practice
    • PID: 22948889, COI: 1:STN:280:DC%2BC38bktFeiug%3D%3D
    • Crews KR, Hicks JK, Pui CH, Relling MV, Evans WE. Pharmacogenomics and individualized medicine: translating science into practice. Clin Pharmacol Ther. 2012;92:467–75.
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 467-475
    • Crews, K.R.1    Hicks, J.K.2    Pui, C.H.3    Relling, M.V.4    Evans, W.E.5
  • 3
    • 85027952177 scopus 로고    scopus 로고
    • Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses
    • PID: 20877299, COI: 1:CAS:528:DC%2BC3cXht1Wjt7zM
    • Fleeman N, Dundar Y, Dickson R, et al. Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses. Pharmacogenomics J. 2011;11:1–14.
    • (2011) Pharmacogenomics J , vol.11 , pp. 1-14
    • Fleeman, N.1    Dundar, Y.2    Dickson, R.3
  • 4
    • 0141791128 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme polymorphisms and adverse drug reactions
    • PID: 14511900, COI: 1:CAS:528:DC%2BD3sXnsVaisbw%3D
    • Pirmohamed M, Park BK. Cytochrome P450 enzyme polymorphisms and adverse drug reactions. Toxicology. 2003;192:23–32.
    • (2003) Toxicology , vol.192 , pp. 23-32
    • Pirmohamed, M.1    Park, B.K.2
  • 5
    • 0031826288 scopus 로고    scopus 로고
    • Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research
    • PID: 9731714, COI: 1:CAS:528:DyaK1cXlvVWqtLc%3D
    • Kalow W, Tang BK, Endrenyi L. Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research. Pharmacogenetics. 1998;8:283–9.
    • (1998) Pharmacogenetics , vol.8 , pp. 283-289
    • Kalow, W.1    Tang, B.K.2    Endrenyi, L.3
  • 6
    • 3042723720 scopus 로고    scopus 로고
    • Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients
    • PID: 15231615
    • Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ. 2004;329:15–9.
    • (2004) BMJ , vol.329 , pp. 15-19
    • Pirmohamed, M.1    James, S.2    Meakin, S.3
  • 7
    • 79952610995 scopus 로고    scopus 로고
    • Market access challenges in the EU for high medical value diagnostic tests
    • Miller I, Ashton-Chess J, Fert V, et al. Market access challenges in the EU for high medical value diagnostic tests. Personal Med. 2011;8:137–48.
    • (2011) Personal Med , vol.8 , pp. 137-148
    • Miller, I.1    Ashton-Chess, J.2    Fert, V.3
  • 8
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalised patients: a meta-analysis of prospective studies
    • PID: 9555760, COI: 1:STN:280:DyaK1c3hsFSnsQ%3D%3D
    • Lazarou J, Pomeranz B, Corey P. Incidence of adverse drug reactions in hospitalised patients: a meta-analysis of prospective studies. JAMA. 1998;279:1200–5.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.2    Corey, P.3
  • 9
    • 84911007288 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalised patients: a meta-analysis of prospective studies
    • Available from
    • Mertens G. Beyond the blcokbuster drug. Business insights. 2005. Available from http://www.pharmatree.in/pdf/reports/Beyond%20the%20Blockbuster%20Drug_Strategies%20for%20nichebuster%20drugs,%20targeted%20therapies%20and%20personalized%20medicine.pdf.
    • (2005) Beyond the blcokbuster drug. Business insights
    • Mertens, G.1
  • 10
    • 79955492923 scopus 로고    scopus 로고
    • Pharmacogenomics: the genetics of variable drug responses
    • PID: 21502584
    • Roden D, Wilke R, Kroemer H, Stein M. Pharmacogenomics: the genetics of variable drug responses. Circulation. 2011;123(15):1661–70.
    • (2011) Circulation , vol.123 , Issue.15 , pp. 1661-1670
    • Roden, D.1    Wilke, R.2    Kroemer, H.3    Stein, M.4
  • 11
    • 80053986227 scopus 로고    scopus 로고
    • Pharmacogenetics and cost-effectiveness analysis: a two-way street
    • PID: 21903176
    • Chalkidou K, Rawlins M. Pharmacogenetics and cost-effectiveness analysis: a two-way street. Drug Discov Today. 2011;16:873–7.
    • (2011) Drug Discov Today , vol.16 , pp. 873-877
    • Chalkidou, K.1    Rawlins, M.2
  • 12
    • 84862726370 scopus 로고    scopus 로고
    • Economic challenges and possible policy actions to advance stratified medicine
    • Trushheim MR, Berndt ER. Economic challenges and possible policy actions to advance stratified medicine. Personalized Med. 2012;9(4):413–27.
    • (2012) Personalized Med , vol.9 , Issue.4 , pp. 413-427
    • Trushheim, M.R.1    Berndt, E.R.2
  • 13
    • 27544503230 scopus 로고    scopus 로고
    • Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
    • PID: 16257339, COI: 1:CAS:528:DC%2BD2MXhtFKhsbfP
    • Thatcher N, Chang A, Parikh P, Pereira JR, Ciuleanu T, von Pawel J, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet. 2005;366:1527–37.
    • (2005) Lancet , vol.366 , pp. 1527-1537
    • Thatcher, N.1    Chang, A.2    Parikh, P.3    Pereira, J.R.4    Ciuleanu, T.5    von Pawel, J.6
  • 14
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • PID: 19692680, COI: 1:CAS:528:DC%2BD1MXhtVygsbfK
    • Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, Saijo N, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361:947–57.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3    Yang, C.H.4    Chu, D.T.5    Saijo, N.6
  • 15
    • 58549095879 scopus 로고    scopus 로고
    • Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses
    • PID: 19106301
    • Di Nicolantonio F, Arena S, Gallicchio M, et al. Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses. Proc Natl Acad Sci. 2008;105:20864–9.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 20864-20869
    • Di Nicolantonio, F.1    Arena, S.2    Gallicchio, M.3
  • 16
    • 84861512598 scopus 로고    scopus 로고
    • How to judge the value of innovation: more evidence is needed but promise; is important early on
    • PID: 22399703
    • Campbell B. How to judge the value of innovation: More evidence is needed but promise; is important early on. BMJ. 2012;344:e1457.
    • (2012) BMJ , vol.344 , pp. e1457
    • Campbell, B.1
  • 17
    • 84911006979 scopus 로고    scopus 로고
    • NICE. Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in early breast cancer management
    • MammaPrint, Oncotype DX, IHC4 and Mammostrat. Available from
    • NICE. Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in early breast cancer management: MammaPrint, Oncotype DX, IHC4 and Mammostrat. Available from http://www.nice.org.uk/nicemedia/live/13283/62767/62767.pdf.
  • 18
    • 36148976077 scopus 로고    scopus 로고
    • Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects
    • PID: 18001838, COI: 1:CAS:528:DC%2BD2sXhtlCrs7bE
    • Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C. Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther. 2007;116:496–526.
    • (2007) Pharmacol Ther , vol.116 , pp. 496-526
    • Ingelman-Sundberg, M.1    Sim, S.C.2    Gomez, A.3    Rodriguez-Antona, C.4
  • 19
    • 84864433575 scopus 로고    scopus 로고
    • Conference scene: is personalized medicine ready for prime time
    • COI: 1:CAS:528:DC%2BC38XhtFSqtb3M
    • Kraus WE, Haga SB, McLeod HL, et al. Conference scene: is personalized medicine ready for prime time. Personalized Med. 2012;9(5):475–8.
    • (2012) Personalized Med , vol.9 , Issue.5 , pp. 475-478
    • Kraus, W.E.1    Haga, S.B.2    McLeod, H.L.3
  • 20
    • 75149160003 scopus 로고    scopus 로고
    • The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation
    • PID: 20031087, COI: 1:STN:280:DC%2BD1Mfkt1Gluw%3D%3D
    • Fleeman N, McLeod C, Bagust A, et al. The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation. Health Technol Assess. 2010;14(3):1–157.
    • (2010) Health Technol Assess , vol.14 , Issue.3 , pp. 1-157
    • Fleeman, N.1    McLeod, C.2    Bagust, A.3
  • 21
    • 80053153296 scopus 로고    scopus 로고
    • The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review
    • Fleeman N, Martin Saborido C, Payne K, et al. The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review. Health Technol Assess. 2011;15(33):1–102.
    • (2011) Health Technol Assess , vol.15 , Issue.33 , pp. 1-102
    • Fleeman, N.1    Martin Saborido, C.2    Payne, K.3
  • 22
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    • PID: 22522925, COI: 1:CAS:528:DC%2BC38XlslSnsL8%3D
    • Curtis C, Shah S, Chin SF, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486:346–52.
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1    Shah, S.2    Chin, S.F.3
  • 23
    • 84883860331 scopus 로고    scopus 로고
    • NICE. NICE to assess high cost drugs for rare conditions
    • Available from
    • NICE. NICE to assess high cost drugs for rare conditions. 2012. Available from http://www.nice.org.uk/newsroom/news/NICEToAssessHighCostDrugsForRareConditions.jsp.
    • (2012)
  • 24
    • 84883454859 scopus 로고    scopus 로고
    • EMA. Guideline on the use of pharmacogenetic methodologies in the pharmacokinetic evaluation of medicinal products
    • Available from
    • EMA. Guideline on the use of pharmacogenetic methodologies in the pharmacokinetic evaluation of medicinal products. 2011. Available from http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2012/02/WC500121954.pdf.
    • (2012)
  • 25
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • PID: 11972444, COI: 1:CAS:528:DC%2BD38XitlWqu70%3D
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics. 2002;3:229–43.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1


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