Huntingtin regulates Ca2+ chemotaxis and K+-facilitated cAMP chemotaxis, in conjunction with the monovalent cation/H+ exchanger Nhe1, in a model developmental system: Insights into its possible role in Huntington's disease

Developmental Biology

Volumn 394, Issue 1, 2014, Pages 24-38

  Wessels, Deborah ^a   Lusche, Daniel F ^a   Scherer, Amanda ^a   Kuhl, Spencer ^a   Myre, Michael A ^b   Soll, David R ^a  

^a UNIVERSITY OF IOWA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Actin myosin cytoskeleton; Calcium chemotaxis; Cation H+ exchanger; Cell motility; Huntingtin; Inositol 1,4,5 trisphosphate receptor; Myosin heavy chain kinase; Nhe1

Indexed keywords

ACTIN; CALCIUM ION; CYCLIC AMP; HUNTINGTIN; POTASSIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; CALCIUM; CATION TRANSPORT PROTEIN; MYOSIN HEAVY CHAIN KINASE; POTASSIUM; PROTOZOAL PROTEIN; SODIUM PROTON EXCHANGE PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM HOMEOSTASIS; CELL AGGREGATION; CELL POPULATION; CHEMOTAXIS; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; GENE CONTROL; GENE DELETION; GENE MUTATION; GENETIC CODE; HTT GENE; HUNTINGTON CHOREA; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRINUCLEOTIDE REPEAT; ACTIN-MYOSIN CYTOSKELETON; CALCIUM CHEMOTAXIS; CATION/H(+) EXCHANGER; CELL MOTILITY; DICTYOSTELIUM; GENETICS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; METABOLISM; NHE1; PHYSIOLOGY;

DICTYOSTELIUM DISCOIDEUM; MAMMALIA;

ACTIN-MYOSIN CYTOSKELETON; CALCIUM CHEMOTAXIS; CATION/H(+) EXCHANGER; CELL MOTILITY; HUNTINGTIN; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; MYOSIN HEAVY CHAIN KINASE; NHE1;

ACTINS; CALCIUM; CATION TRANSPORT PROTEINS; CELL AGGREGATION; CHEMOTAXIS; CYCLIC AMP; DICTYOSTELIUM; GENE DELETION; HUNTINGTON DISEASE; POTASSIUM; PROTOZOAN PROTEINS; SODIUM-HYDROGEN ANTIPORTER;

EID: 84911004350     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.08.009     Document Type: Article

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