Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans

Synapse

Volumn 69, Issue 1, 2015, Pages 33-40

  Joshi, Aniket D ^a   Sanabria Bohórquez, Sandra M ^a   Bormans, Guy ^b   Koole, Michel ^c   De Hoon, Jan ^b   Van Hecken, Anne ^b   Depre, Marleen ^b   De Lepeleire, Inge ^d   Van Laere, Koen ^b   Sur, Cyrille ^a   Hamill, Terence G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d MSD Europe Inc   (Belgium)

Author keywords

Glycine transporter 1 receptor; GlyT1 receptor PET tracer; Population input function; Proof of concept studies

Indexed keywords

BENZAMIDE DERIVATIVE; GLYCINE TRANSPORTER; MK-6577; RADIOPHARMACEUTICAL AGENT; SLC6A9 PROTEIN, HUMAN; SULFONAMIDE;

ADULT; ANTAGONISTS AND INHIBITORS; BRAIN; BRAIN MAPPING; COHORT ANALYSIS; DIAGNOSTIC USE; DRUG EFFECTS; HUMAN; KINETICS; MALE; METABOLISM; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; REPRODUCIBILITY; SCINTISCANNING; YOUNG ADULT;

ADULT; BENZAMIDES; BRAIN; BRAIN MAPPING; COHORT STUDIES; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; KINETICS; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SULFONAMIDES; YOUNG ADULT;

EID: 84910660354     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.21782     Document Type: Article

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