Quantification of the glycine transporter 1 in rhesus monkey brain using [ 18F]MK-6577 and a model-based input function

NeuroImage

Volumn 59, Issue 3, 2012, Pages 2589-2599

  Sanabria Bohórquez, Sandra M ^a   Joshi, Aniket D ^a   Holahan, Marie ^a   Daneker, Lori ^a   Riffel, Kerry ^a   Williams, Mangay ^a   Li, Wenping ^a   Cook, Jacquelynn J ^a   Hamill, Terence G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

18F MK 6577; Glycine transporter 1 (GlyT1); Lassen plot; Model based input function; Positron emission tomography; Tracer kinetic modeling

Indexed keywords

GLYCINE TRANSPORTER 1; MK 6577 F 18; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PROTEIN BINDING; IN VIVO STUDY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; RHESUS MONKEY;

ALGORITHMS; ANIMALS; BRAIN; BRAIN CHEMISTRY; CORPUS STRIATUM; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; FLUORINE RADIOISOTOPES; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; MACACA MULATTA; MODELS, NEUROLOGICAL; MODELS, STATISTICAL; POSITRON-EMISSION TOMOGRAPHY; RECEPTORS, N-METHYL-D-ASPARTATE; THALAMUS;

EID: 84855461457     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2011.08.080     Document Type: Article

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