-
2
-
-
0033621925
-
Pharmacokinetic profile of levetiracetam: Toward ideal characteristics
-
Patsalos PN (2000) Pharmacokinetic profile of levetiracetam: toward ideal characteristics. Pharmacol Ther 85:77-85.
-
(2000)
Pharmacol Ther
, vol.85
, pp. 77-85
-
-
Patsalos, P.N.1
-
3
-
-
0037353797
-
The pharmacokinetic characteristics of levetiracetam
-
Patsalos PN (2003) The pharmacokinetic characteristics of levetiracetam. Methods Find Exp Clin Pharmacol 25:123-129.
-
(2003)
Methods Find Exp Clin Pharmacol
, vol.25
, pp. 123-129
-
-
Patsalos, P.N.1
-
4
-
-
4344639324
-
Clinical pharmacokinetics of levetiracetam
-
Patsalos PN (2004) Clinical pharmacokinetics of levetiracetam. Clin Pharmacokinet 43:707-724.
-
(2004)
Clin Pharmacokinet
, vol.43
, pp. 707-724
-
-
Patsalos, P.N.1
-
5
-
-
33750924438
-
In situ metabolism of levetiracetam in blood of patients with epilepsy
-
Patsalos PN, Ghattaura S, Ratnaraj N, Sander JW (2006) In situ metabolism of levetiracetam in blood of patients with epilepsy. Epilepsia 47:1818-1821.
-
(2006)
Epilepsia
, vol.47
, pp. 1818-1821
-
-
Patsalos, P.N.1
Ghattaura, S.2
Ratnaraj, N.3
Sander, J.W.4
-
6
-
-
0344198468
-
Serum concentrations of Levetiracetam in epileptic patients: The influence of dose and co-medication
-
May TW, Rambeck B, Jurgens U (2003) Serum concentrations of Levetiracetam in epileptic patients: the influence of dose and co-medication. Ther Drug Monit 25:690-699.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 690-699
-
-
May, T.W.1
Rambeck, B.2
Jurgens, U.3
-
7
-
-
84886769149
-
Drug interactions with the newer antiepileptic drugs (AEDs) - Part 1: Pharmacokinetic and pharmacodynamic interactions between AEDs
-
Patsalos PN (2013) Drug interactions with the newer antiepileptic drugs (AEDs) - part 1: pharmacokinetic and pharmacodynamic interactions between AEDs. Clin Pharmacokinet 52:927-966.
-
(2013)
Clin Pharmacokinet
, vol.52
, pp. 927-966
-
-
Patsalos, P.N.1
-
8
-
-
84890527382
-
Drug interactions with the newer antiepileptic drugs (AEDs) - Part 2: Pharmacokinetic and pharmacodynamic interactions between AEDs and drugs used to treat non-epilepsy disorders
-
Patsalos PN (2013) Drug interactions with the newer antiepileptic drugs (AEDs) - Part 2: pharmacokinetic and pharmacodynamic interactions between AEDs and drugs used to treat non-epilepsy disorders. Clin Pharmacokinet 52:1045-1061.
-
(2013)
Clin Pharmacokinet
, vol.52
, pp. 1045-1061
-
-
Patsalos, P.N.1
-
9
-
-
34848887217
-
Therapeutic drug monitoring of levetiracetam by high-performance liquid chromatography with photodiode array ultraviolet detection: Preliminary observations on correlation between plasma concentration and clinical response in patients with refractory epilepsy
-
Lancelin F, Franchon E, Kraoul L, Garciau I, Brovedani S, et al. (2007) Therapeutic drug monitoring of levetiracetam by high-performance liquid chromatography with photodiode array ultraviolet detection: preliminary observations on correlation between plasma concentration and clinical response in patients with refractory epilepsy. Ther Drug Monit 29:576-583.
-
(2007)
Ther Drug Monit
, vol.29
, pp. 576-583
-
-
Lancelin, F.1
Franchon, E.2
Kraoul, L.3
Garciau, I.4
Brovedani, S.5
-
10
-
-
84882770998
-
Apparent dose-dependent levetiracetam-induced de novo major depression with suicidal behavior
-
Kaufman KR, Bisen V, Zimmerman A, Tobia A, Mani R, et al. (2013) Apparent dose-dependent levetiracetam-induced de novo major depression with suicidal behavior. Epilepsy and Behavior Case Reports 1:110-112.
-
(2013)
Epilepsy and Behavior Case Reports
, vol.1
, pp. 110-112
-
-
Kaufman, K.R.1
Bisen, V.2
Zimmerman, A.3
Tobia, A.4
Mani, R.5
-
11
-
-
45749150011
-
Antiepileptic drugs-best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies
-
2008/04/10 ed
-
Patsalos PN, Berry DJ, Bourgeois BF, Cloyd JC, Glauser TA, et al. (2008) Antiepileptic drugs-best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies. Epilepsia. 2008/04/10 ed. pp. 1239-1276.
-
(2008)
Epilepsia
, pp. 1239-1276
-
-
Patsalos, P.N.1
Berry, D.J.2
Bourgeois, B.F.3
Cloyd, J.C.4
Glauser, T.A.5
-
12
-
-
78751646276
-
Performance characteristics of a new levetiracetam immunoassay and method comparison with a high-performance liquid chromatography method
-
Reineks EZ, Lawson SE, Lembright KE, Wang S (2011) Performance characteristics of a new levetiracetam immunoassay and method comparison with a high-performance liquid chromatography method. Ther Drug Monit 33:124-127.
-
(2011)
Ther Drug Monit
, vol.33
, pp. 124-127
-
-
Reineks, E.Z.1
Lawson, S.E.2
Lembright, K.E.3
Wang, S.4
-
13
-
-
84874782463
-
A simple bioanalytical method for the quantification of antiepileptic drugs in dried blood spots
-
Shah NM, Hawwa AF, Millership JS, Collier PS, McElnay JC (2013) A simple bioanalytical method for the quantification of antiepileptic drugs in dried blood spots. J Chromatogr B Analyt Technol Biomed Life Sci 923-924:65-73.
-
(2013)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.923-924
, pp. 65-73
-
-
Shah, N.M.1
Hawwa, A.F.2
Millership, J.S.3
Collier, P.S.4
McElnay, J.C.5
-
14
-
-
84859930678
-
Determination of ng/mL levetiracetam using ultra-high-performance liquid chromatography-photodiode absorbance
-
Olah E, Bacsoi G, Fekete J, Sharma VK (2012) Determination of ng/mL levetiracetam using ultra-high-performance liquid chromatography-photodiode absorbance. J Chromatogr Sci 50:253-258.
-
(2012)
J Chromatogr Sci
, vol.50
, pp. 253-258
-
-
Olah, E.1
Bacsoi, G.2
Fekete, J.3
Sharma, V.K.4
-
15
-
-
81155162541
-
Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma
-
Antonilli L, Brusadin V, Filipponi F, Guglielmi R, Nencini P (2011) Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma. J Pharm Biomed Anal 56:763-770.
-
(2011)
J Pharm Biomed Anal
, vol.56
, pp. 763-770
-
-
Antonilli, L.1
Brusadin, V.2
Filipponi, F.3
Guglielmi, R.4
Nencini, P.5
-
16
-
-
76749108393
-
LC method for therapeutic drug monitoring of levetiracetam: Evaluation of the assay performance and validation of its application in the routine area
-
Zufia L, Aldaz A, Ibanez N, Giraldez J, Viteri C (2010) LC method for therapeutic drug monitoring of levetiracetam: evaluation of the assay performance and validation of its application in the routine area. Clin Biochem 43:473-482.
-
(2010)
Clin Biochem
, vol.43
, pp. 473-482
-
-
Zufia, L.1
Aldaz, A.2
Ibanez, N.3
Giraldez, J.4
Viteri, C.5
-
17
-
-
50849118789
-
Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy
-
Contin M, Mohamed S, Albani F, Riva R, Baruzzi A (2008) Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy. J Chromatogr B Analyt Technol Biomed Life Sci 873:129-132.
-
(2008)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.873
, pp. 129-132
-
-
Contin, M.1
Mohamed, S.2
Albani, F.3
Riva, R.4
Baruzzi, A.5
-
18
-
-
33646171308
-
Drug monitoring and toxicology: A procedure for the monitoring of levetiracetam and zonisamide by HPLC-UV
-
Juenke J, Brown PI, Urry FM, McMillin GA (2006) Drug monitoring and toxicology: a procedure for the monitoring of levetiracetam and zonisamide by HPLC-UV. J Anal Toxicol 30:27-30.
-
(2006)
J Anal Toxicol
, vol.30
, pp. 27-30
-
-
Juenke, J.1
Brown, P.I.2
Urry, F.M.3
McMillin, G.A.4
-
20
-
-
1142263160
-
Highperformance liquid chromatographic determination of Levetiracetam in human plasma: Comparison of different sample clean-up procedures
-
Pucci V, Bugamelli F, Mandrioli R, Ferranti A, Kenndler E, et al. (2004) Highperformance liquid chromatographic determination of Levetiracetam in human plasma: comparison of different sample clean-up procedures. Biomed Chromatogr 18:37-44.
-
(2004)
Biomed Chromatogr
, vol.18
, pp. 37-44
-
-
Pucci, V.1
Bugamelli, F.2
Mandrioli, R.3
Ferranti, A.4
Kenndler, E.5
-
21
-
-
0037306316
-
Correlation of levetiracetam concentrations between serum and saliva
-
Grim SA, Ryan M, Miles MV, Tang PH, Strawsburg RH, et al. (2003) Correlation of levetiracetam concentrations between serum and saliva. Ther Drug Monit 25:61-66.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 61-66
-
-
Grim, S.A.1
Ryan, M.2
Miles, M.V.3
Tang, P.H.4
Strawsburg, R.H.5
-
22
-
-
0029945589
-
A micromethod for the determination of the new antiepileptic drug levetiracetam (ucb LO59) in serum or plasma by high performance liquid chromatography
-
Ratnaraj N, Doheny HC, Patsalos PN (1996) A micromethod for the determination of the new antiepileptic drug levetiracetam (ucb LO59) in serum or plasma by high performance liquid chromatography. Ther Drug Monit 18:154-157.
-
(1996)
Ther Drug Monit
, vol.18
, pp. 154-157
-
-
Ratnaraj, N.1
Doheny, H.C.2
Patsalos, P.N.3
-
23
-
-
0028044191
-
High-performance liquid chromatographic and megabore gas-liquid chromatographic determination of levetiracetam (ucb L059) in human serum after solid-phase extraction
-
Vermeij TA, Edelbroek PM (1994) High-performance liquid chromatographic and megabore gas-liquid chromatographic determination of levetiracetam (ucb L059) in human serum after solid-phase extraction. J Chromatogr B Biomed Appl 662:134-139.
-
(1994)
J Chromatogr B Biomed Appl
, vol.662
, pp. 134-139
-
-
Vermeij, T.A.1
Edelbroek, P.M.2
-
24
-
-
77956154787
-
Reversed-phase HPLC analysis of levetiracetam in tablets using monolithic and conventional C18 silica columns
-
Can NO, Arli G (2010) Reversed-phase HPLC analysis of levetiracetam in tablets using monolithic and conventional C18 silica columns. J AOAC Int 93:1077-1085.
-
(2010)
J AOAC Int
, vol.93
, pp. 1077-1085
-
-
Can, N.O.1
Arli, G.2
-
25
-
-
34447510947
-
Saliva and serum levetiracetam concentrations in patients with epilepsy
-
Mecarelli O, Li Voti P, Pro S, Romolo FS, Rotolo M, et al. (2007) Saliva and serum levetiracetam concentrations in patients with epilepsy. Ther Drug Monit 29:313-318.
-
(2007)
Ther Drug Monit
, vol.29
, pp. 313-318
-
-
Mecarelli, O.1
Li Voti, P.2
Pro, S.3
Romolo, F.S.4
Rotolo, M.5
-
26
-
-
0034683005
-
Enantioselective analysis of levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide using gas chromatography and ion trap mass spectrometric detection
-
Isoherranen N, Roeder M, Soback S, Yagen B, Schurig V, et al. (2000) Enantioselective analysis of levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide using gas chromatography and ion trap mass spectrometric detection. J Chromatogr B Biomed Sci Appl 745:325-332.
-
(2000)
J Chromatogr B Biomed Sci Appl
, vol.745
, pp. 325-332
-
-
Isoherranen, N.1
Roeder, M.2
Soback, S.3
Yagen, B.4
Schurig, V.5
-
27
-
-
20444458809
-
Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): Characterization by dynamic liver function tests
-
Brockmoller J, Thomsen T, Wittstock M, Coupez R, Lochs H, et al. (2005) Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests. Clin Pharmacol Ther 77:529-541.
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 529-541
-
-
Brockmoller, J.1
Thomsen, T.2
Wittstock, M.3
Coupez, R.4
Lochs, H.5
-
28
-
-
0037322794
-
Levetiracetam, a new antiepileptic agent: Lack of in vitro and in vivo pharmacokinetic interaction with valproic acid
-
Coupez R, Nicolas JM, Browne TR (2003) Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid. Epilepsia 44:171-178.
-
(2003)
Epilepsia
, vol.44
, pp. 171-178
-
-
Coupez, R.1
Nicolas, J.M.2
Browne, T.R.3
-
29
-
-
0347765635
-
Microemulsion electrokinetic chromatography applied for separation of levetiracetam from other antiepileptic drugs in polypharmacy
-
Ivanova M, Piunti A, Marziali E, Komarova N, Raggi MA, et al. (2003) Microemulsion electrokinetic chromatography applied for separation of levetiracetam from other antiepileptic drugs in polypharmacy. Electrophoresis 24:992-998.
-
(2003)
Electrophoresis
, vol.24
, pp. 992-998
-
-
Ivanova, M.1
Piunti, A.2
Marziali, E.3
Komarova, N.4
Raggi, M.A.5
-
30
-
-
84881290076
-
A simple assay for determination of levetiracetam in rat dried blood spots by LC-MS/MS
-
Luo W, Kong ST, Yang S, Chan BC, Ho PC (2013) A simple assay for determination of levetiracetam in rat dried blood spots by LC-MS/MS. Bioanalysis 5:1843-1851.
-
(2013)
Bioanalysis
, vol.5
, pp. 1843-1851
-
-
Luo, W.1
Kong, S.T.2
Yang, S.3
Chan, B.C.4
Ho, P.C.5
-
31
-
-
84865310944
-
Analysis of selected anticonvulsants by high performance liquid chromatography-tandem mass spectrometry
-
Collins JA, Janis GC (2012) Analysis of selected anticonvulsants by high performance liquid chromatography-tandem mass spectrometry. Methods Mol Biol 902:201-209.
-
(2012)
Methods Mol Biol
, vol.902
, pp. 201-209
-
-
Collins, J.A.1
Janis, G.C.2
-
32
-
-
76749105200
-
Simultaneous determination of levetiracetam and its acid metabolite (ucb L057) in serum/plasma by liquid chromatography tandem mass spectrometry
-
Mendu DR, Soldin SJ (2010) Simultaneous determination of levetiracetam and its acid metabolite (ucb L057) in serum/plasma by liquid chromatography tandem mass spectrometry. Clin Biochem 43:485-489.
-
(2010)
Clin Biochem
, vol.43
, pp. 485-489
-
-
Mendu, D.R.1
Soldin, S.J.2
-
33
-
-
53049094637
-
Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: Application to therapeutic drug monitoring
-
Matar KM (2008) Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: application to therapeutic drug monitoring. J Pharm Biomed Anal 48:822-828.
-
(2008)
J Pharm Biomed Anal
, vol.48
, pp. 822-828
-
-
Matar, K.M.1
-
34
-
-
84860388858
-
Simple and accurate quantitative analysis of ten antiepileptic drugs in human plasma by liquid chromatography/tandem mass spectrometry
-
Kim KB, Seo KA, Kim SE, Bae SK, Kim DH, et al. (2011) Simple and accurate quantitative analysis of ten antiepileptic drugs in human plasma by liquid chromatography/tandem mass spectrometry. J Pharm Biomed Anal 56:771-777.
-
(2011)
J Pharm Biomed Anal
, vol.56
, pp. 771-777
-
-
Kim, K.B.1
Seo, K.A.2
Kim, S.E.3
Bae, S.K.4
Kim, D.H.5
-
35
-
-
33750066632
-
Determination of levetiracetam in human plasma/serum/saliva by liquid chromatographyelectrospray tandem mass spectrometry
-
Guo T, Oswald LM, Mendu DR, Soldin SJ (2007) Determination of levetiracetam in human plasma/serum/saliva by liquid chromatographyelectrospray tandem mass spectrometry. Clin Chim Acta 375:115-118.
-
(2007)
Clin Chim Acta
, vol.375
, pp. 115-118
-
-
Guo, T.1
Oswald, L.M.2
Mendu, D.R.3
Soldin, S.J.4
-
36
-
-
33748285990
-
Determination of levetiracetam in human plasma by liquid chromatography/electrospray tandem mass spectrometry and its application to bioequivalence studies
-
Jain DS, Subbaiah G, Sanyal M, Pal U, Shrivastav PS (2006) Determination of levetiracetam in human plasma by liquid chromatography/electrospray tandem mass spectrometry and its application to bioequivalence studies. Rapid Commun Mass Spectrom 20:2539-2547.
-
(2006)
Rapid Commun Mass Spectrom
, vol.20
, pp. 2539-2547
-
-
Jain, D.S.1
Subbaiah, G.2
Sanyal, M.3
Pal, U.4
Shrivastav, P.S.5
-
37
-
-
84881450725
-
Fully validated method for rapid and simultaneous measurement of six antiepileptic drugs in serum and plasma using ultraperformance liquid chromatography-electrospray ionization tandem mass spectrometry
-
Kuhn J, Knabbe C (2013) Fully validated method for rapid and simultaneous measurement of six antiepileptic drugs in serum and plasma using ultraperformance liquid chromatography-electrospray ionization tandem mass spectrometry. Talanta 110:71-80.
-
(2013)
Talanta
, vol.110
, pp. 71-80
-
-
Kuhn, J.1
Knabbe, C.2
-
38
-
-
84867740189
-
Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring
-
Shibata M, Hashi S, Nakanishi H, Masuda S, Katsura T, et al. (2012) Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring. Biomed Chromatogr 26:1519-1528.
-
(2012)
Biomed Chromatogr
, vol.26
, pp. 1519-1528
-
-
Shibata, M.1
Hashi, S.2
Nakanishi, H.3
Masuda, S.4
Katsura, T.5
-
39
-
-
79953186567
-
Simultaneous quantification of levetiracetam and gabapentin in plasma by ultra-pressure liquid chromatography coupled with tandem mass spectrometry detection
-
Juenke JM, Brown PI, Johnson-Davis KL, McMillin GA (2011) Simultaneous quantification of levetiracetam and gabapentin in plasma by ultra-pressure liquid chromatography coupled with tandem mass spectrometry detection. Ther Drug Monit 33:209-213.
-
(2011)
Ther Drug Monit
, vol.33
, pp. 209-213
-
-
Juenke, J.M.1
Brown, P.I.2
Johnson-Davis, K.L.3
McMillin, G.A.4
-
41
-
-
0035675738
-
Pharmacokinetic study of levetiracetam in children
-
Pellock JM, Glauser TA, Bebin EM, Fountain NB, Ritter FJ, et al. (2001) Pharmacokinetic study of levetiracetam in children. Epilepsia 42:1574-1579.
-
(2001)
Epilepsia
, vol.42
, pp. 1574-1579
-
-
Pellock, J.M.1
Glauser, T.A.2
Bebin, E.M.3
Fountain, N.B.4
Ritter, F.J.5
-
44
-
-
34249807897
-
Pharmacokinetics of levetiracetam in infants and young children with epilepsy
-
Glauser TA, Mitchell WG, Weinstock A, Bebin M, Chen D, et al. (2007) Pharmacokinetics of levetiracetam in infants and young children with epilepsy. Epilepsia 48:1117-1122.
-
(2007)
Epilepsia
, vol.48
, pp. 1117-1122
-
-
Glauser, T.A.1
Mitchell, W.G.2
Weinstock, A.3
Bebin, M.4
Chen, D.5
-
45
-
-
33947244366
-
Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate
-
Fountain NB, Conry JA, Rodriguez-Leyva I, Gutierrez-Moctezuma J, Salas E, et al. (2007) Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate. Epilepsy Res 74:60-69.
-
(2007)
Epilepsy Res
, vol.74
, pp. 60-69
-
-
Fountain, N.B.1
Conry, J.A.2
Rodriguez-Leyva, I.3
Gutierrez-Moctezuma, J.4
Salas, E.5
|