Enantioselective analysis of levetiracetam and its enantiomer R-α- ethyl-2-oxo-pyrrolidine acetamide using gas chromatography and ion trap mass spectrometric detection

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 745, Issue 2, 2000, Pages 325-332

  Isoherranen, Nina ^a   Roeder, Michael ^b   Soback, Stefan ^c   Yagen, Boris ^a,d   Schurig, Volker ^b   Bialer, Meir ^a,b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c KIMRON VETERINARY INSTITUTE   (Israel)

^d David R Bloom Center for Pharmacy   (Israel)

Author keywords

Enantiomer separation; Levetiracetam; R ( ) ethyl 2 oxo pyrrolidine acetamide

Indexed keywords

CYCLODEXTRIN; ETIRACETAM;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CHIRALITY; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG URINE LEVEL; ENANTIOMER; GAS CHROMATOGRAPHY; ION MONITORING; MASS SPECTROMETRY; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SOLID PHASE EXTRACTION; STEREOCHEMISTRY; VALIDATION PROCESS;

ANIMALS; DOGS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; PIRACETAM; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 0034683005     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(00)00293-0     Document Type: Article

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