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Volumn 30, Issue 8, 2014, Pages 707-715

Modifiable clinical and lifestyle factors are associated with elevated alanine aminotransferase levels in newly diagnosed type 2 diabetes patients: Results from the nationwide DD2 study

Author keywords

Alanine aminotransferase; DD2 study; Lifestyle factors; Markers; Non alcoholic fatty liver disease; Type 2 diabetes mellitus

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ANTIHYPERTENSIVE AGENT; BIOLOGICAL MARKER; C PEPTIDE; GLUCOSE; INSULIN;

EID: 84910651912     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2539     Document Type: Article
Times cited : (16)

References (42)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Medical progress - nonalcoholic fatty liver disease
    • Angulo P. Medical progress - nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-1231.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 3
    • 33846264060 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: the plot thickens
    • Targher G. Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: the plot thickens. Diabet Med 2007; 24: 1-6.
    • (2007) Diabet Med , vol.24 , pp. 1-6
    • Targher, G.1
  • 4
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
    • Grundy SM, Brewer HB Jr, Cleeman JI, et al. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 2004; 109(3): 433-438.
    • (2004) Circulation , vol.109 , Issue.3 , pp. 433-438
    • Grundy, S.M.1    Brewer Jr, H.B.2    Cleeman, J.I.3
  • 6
    • 33947366047 scopus 로고    scopus 로고
    • Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: the Hoorn Study
    • Schindhelm RK, Dekker JM, Nijpels G, et al. Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: the Hoorn Study. Diabet Med 2007; 24: 430-435.
    • (2007) Diabet Med , vol.24 , pp. 430-435
    • Schindhelm, R.K.1    Dekker, J.M.2    Nijpels, G.3
  • 7
    • 33644693579 scopus 로고    scopus 로고
    • Liver markers and development of the metabolic syndrome: the insulin resistance atherosclerosis study
    • Hanley AJ, Williams K, Festa A, Wagenknecht LE, D'Agostino RB Jr, Haffner SM. Liver markers and development of the metabolic syndrome: the insulin resistance atherosclerosis study. Diabetes 2005; 54: 3140-3147.
    • (2005) Diabetes , vol.54 , pp. 3140-3147
    • Hanley, A.J.1    Williams, K.2    Festa, A.3    Wagenknecht, L.E.4    D'Agostino Jr, R.B.5    Haffner, S.M.6
  • 9
    • 77954424925 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study
    • Adams LA, Harmsen S, St Sauver JL, et al. Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study. Am J Gastroenterol 2010; 105: 1567-1573.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1567-1573
    • Adams, L.A.1    Harmsen, S.2    St Sauver, J.L.3
  • 10
    • 77952785795 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease from pathogenesis to management: an update
    • Musso G, Gambino R, Cassader M. Non-alcoholic fatty liver disease from pathogenesis to management: an update. Obes Rev 2010; 11: 430-445.
    • (2010) Obes Rev , vol.11 , pp. 430-445
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 11
    • 21344449292 scopus 로고    scopus 로고
    • Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study
    • Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini G, Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology 2005; 42: 44-52.
    • (2005) Hepatology , vol.42 , pp. 44-52
    • Bedogni, G.1    Miglioli, L.2    Masutti, F.3    Tiribelli, C.4    Marchesini, G.5    Bellentani, S.6
  • 13
    • 70549105648 scopus 로고    scopus 로고
    • Independent predictors of fibrosis in patients with nonalcoholic fatty liver disease
    • Hossain N, Afendy A, Stepanova M, et al. Independent predictors of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2009; 7: 1224-1229.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1224-1229
    • Hossain, N.1    Afendy, A.2    Stepanova, M.3
  • 14
    • 66149088144 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in type 2 diabetes mellitus
    • Cusi K. Nonalcoholic fatty liver disease in type 2 diabetes mellitus. Curr Opin Endocrinol Diabetes Obes 2009; 16: 141-149.
    • (2009) Curr Opin Endocrinol Diabetes Obes , vol.16 , pp. 141-149
    • Cusi, K.1
  • 15
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003; 98: 960-967.
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 16
    • 0037733958 scopus 로고    scopus 로고
    • Elevated AST or ALT to nonalcoholic fatty liver disease: accurate predictor of disease prevalence?
    • Yu AS, Keeffe EB. Elevated AST or ALT to nonalcoholic fatty liver disease: accurate predictor of disease prevalence? Am J Gastroenterol 2003; 98: 955-956.
    • (2003) Am J Gastroenterol , vol.98 , pp. 955-956
    • Yu, A.S.1    Keeffe, E.B.2
  • 17
    • 84885166200 scopus 로고    scopus 로고
    • Noninvasive biomarkers for the diagnosis of steatohepatitis and advanced fibrosis in NAFLD
    • Pearce SG, Thosani NC, Pan JJ. Noninvasive biomarkers for the diagnosis of steatohepatitis and advanced fibrosis in NAFLD. Biomarker Res 2013; 1(1). doi:10.1186/2050-7771-1-7.
    • (2013) Biomarker Res , vol.1 , Issue.1
    • Pearce, S.G.1    Thosani, N.C.2    Pan, J.J.3
  • 18
    • 42549173662 scopus 로고    scopus 로고
    • Prevalence of elevated liver enzymes in type 2 diabetes mellitus and its association with the metabolic syndrome
    • Forlani G, Di Bonito P, Mannucci E, et al. Prevalence of elevated liver enzymes in type 2 diabetes mellitus and its association with the metabolic syndrome. J Endocrinol Invest 2008; 31: 146-152.
    • (2008) J Endocrinol Invest , vol.31 , pp. 146-152
    • Forlani, G.1    Di Bonito, P.2    Mannucci, E.3
  • 19
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010; 87: 4-14.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 20
    • 18344376371 scopus 로고    scopus 로고
    • Trends in liver disease prevalence in Mexico from 2005 to 2050 through mortality data
    • Mendez-Sanchez N, Villa AR, Chavez-Tapia NC, et al. Trends in liver disease prevalence in Mexico from 2005 to 2050 through mortality data. Ann Hepatol 2005; 4: 52-55.
    • (2005) Ann Hepatol , vol.4 , pp. 52-55
    • Mendez-Sanchez, N.1    Villa, A.R.2    Chavez-Tapia, N.C.3
  • 21
    • 84866674756 scopus 로고    scopus 로고
    • The Danish Centre for Strategic Research in Type 2 Diabetes (DD2): organization of diabetes care in Denmark and supplementary data sources for data collection among DD2 study participants
    • Thomsen RW, Friborg S, Nielsen JS, Schroll H, Johnsen SP. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2): organization of diabetes care in Denmark and supplementary data sources for data collection among DD2 study participants. Clin Epidemiol 2012; 4: 15-19.
    • (2012) Clin Epidemiol , vol.4 , pp. 15-19
    • Thomsen, R.W.1    Friborg, S.2    Nielsen, J.S.3    Schroll, H.4    Johnsen, S.P.5
  • 22
    • 84866647608 scopus 로고    scopus 로고
    • The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: implementation of a nationwide patient enrollment system
    • Nielsen JS, Thomsen RW, Steffensen C, Christiansen JS. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: implementation of a nationwide patient enrollment system. Clin Epidemiol 2012; 4: 27-36.
    • (2012) Clin Epidemiol , vol.4 , pp. 27-36
    • Nielsen, J.S.1    Thomsen, R.W.2    Steffensen, C.3    Christiansen, J.S.4
  • 23
    • 84866687776 scopus 로고    scopus 로고
    • The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: collection of baseline data from the first 580 patients
    • Thomsen RW, Nielsen JS, Ulrichsen SP, Pedersen L, Hansen AM, Nilsson T. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: collection of baseline data from the first 580 patients. Clin Epidemiol 2012; 4: 43-48.
    • (2012) Clin Epidemiol , vol.4 , pp. 43-48
    • Thomsen, R.W.1    Nielsen, J.S.2    Ulrichsen, S.P.3    Pedersen, L.4    Hansen, A.M.5    Nilsson, T.6
  • 25
    • 0032999949 scopus 로고    scopus 로고
    • The Danish National Hospital Register. a valuable source of data for modern health sciences
    • Andersen TF, Madsen M, Jorgensen J, Mellemkjoer L, Olsen JH. The Danish National Hospital Register. a valuable source of data for modern health sciences. Dan Med Bull 1999; 46(3): 263-268.
    • (1999) Dan Med Bull , vol.46 , Issue.3 , pp. 263-268
    • Andersen, T.F.1    Madsen, M.2    Jorgensen, J.3    Mellemkjoer, L.4    Olsen, J.H.5
  • 27
    • 33751395235 scopus 로고    scopus 로고
    • The Danish Civil Registration System. A cohort of eight million persons
    • Pedersen CB, Gotzsche H, Moller JO, Mortensen PB. The Danish Civil Registration System. A cohort of eight million persons. Dan Med Bull 2006; 53: 441-449.
    • (2006) Dan Med Bull , vol.53 , pp. 441-449
    • Pedersen, C.B.1    Gotzsche, H.2    Moller, J.O.3    Mortensen, P.B.4
  • 28
    • 0027772612 scopus 로고
    • Recommendations for carrying out standard ECCLS procedures (1988) for the catalytic concentrations of creatine kinase, aspartate aminotransferase, alanine aminotransferase and gamma-glutamyltransferase at 37 degrees C. Standardization Committee of the German Society for Clinical Chemistry, Enzyme Working Group of the German Society for Clinical Chemistry
    • Klauke R, Schmidt E, Lorentz K. Recommendations for carrying out standard ECCLS procedures (1988) for the catalytic concentrations of creatine kinase, aspartate aminotransferase, alanine aminotransferase and gamma-glutamyltransferase at 37 degrees C. Standardization Committee of the German Society for Clinical Chemistry, Enzyme Working Group of the German Society for Clinical Chemistry. Eur J Clin Chem Clin Biochem 1993; 31(12): 901-909.
    • (1993) Eur J Clin Chem Clin Biochem , vol.31 , Issue.12 , pp. 901-909
    • Klauke, R.1    Schmidt, E.2    Lorentz, K.3
  • 29
    • 0029038830 scopus 로고
    • Health-based reference intervals for ALT, ASAT and GT in serum, measured according to the recommendations of the European Committee for Clinical Laboratory Standards (ECCLS)
    • Leino A, Impivaara O, Irjala K, Maki J, Peltola O, Jarvisalo J. Health-based reference intervals for ALT, ASAT and GT in serum, measured according to the recommendations of the European Committee for Clinical Laboratory Standards (ECCLS). Scand J Clin Lab Invest 1995; 55(3): 243-250.
    • (1995) Scand J Clin Lab Invest , vol.55 , Issue.3 , pp. 243-250
    • Leino, A.1    Impivaara, O.2    Irjala, K.3    Maki, J.4    Peltola, O.5    Jarvisalo, J.6
  • 30
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3
  • 31
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: development and validation
    • Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373-383.
    • (1987) J Chronic Dis , vol.40 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.L.3    MacKenzie, C.R.4
  • 32
    • 79957533297 scopus 로고    scopus 로고
    • The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients
    • Thygesen SK, Christiansen CF, Christensen S, Lash TL, Sorensen HT. The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol 2011; 11: 83.
    • (2011) BMC Med Res Methodol , vol.11 , pp. 83
    • Thygesen, S.K.1    Christiansen, C.F.2    Christensen, S.3    Lash, T.L.4    Sorensen, H.T.5
  • 33
    • 49649088692 scopus 로고    scopus 로고
    • Diabetes, glycemic control, and risk of hospitalization with pneumonia: a population-based case-control study
    • Kornum JB, Thomsen RW, Riis A, Lervang HH, Schonheyder HC, Sorensen HT. Diabetes, glycemic control, and risk of hospitalization with pneumonia: a population-based case-control study. Diabetes Care 2008; 31: 1541-1545.
    • (2008) Diabetes Care , vol.31 , pp. 1541-1545
    • Kornum, J.B.1    Thomsen, R.W.2    Riis, A.3    Lervang, H.H.4    Schonheyder, H.C.5    Sorensen, H.T.6
  • 34
    • 0030940965 scopus 로고    scopus 로고
    • Alcohol consumption and serum liver-derived enzymes in a Danish population aged 30-50 years
    • Steffensen FH, Sorensen HT, Brock A, Vilstrup H, Lauritzen T. Alcohol consumption and serum liver-derived enzymes in a Danish population aged 30-50 years. Int J Epidemiol 1997; 26: 92-99.
    • (1997) Int J Epidemiol , vol.26 , pp. 92-99
    • Steffensen, F.H.1    Sorensen, H.T.2    Brock, A.3    Vilstrup, H.4    Lauritzen, T.5
  • 35
    • 84887465160 scopus 로고    scopus 로고
    • Raised liver enzymes in newly diagnosed type 2 diabetes are associated with weight and lipids, but not glycaemic control
    • Saligram S, Williams EJ, Masding MG. Raised liver enzymes in newly diagnosed type 2 diabetes are associated with weight and lipids, but not glycaemic control. Indian J Endocrinol Metab 2012; 16: 1012-1014.
    • (2012) Indian J Endocrinol Metab , vol.16 , pp. 1012-1014
    • Saligram, S.1    Williams, E.J.2    Masding, M.G.3
  • 36
    • 0035431018 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a feature of the metabolic syndrome
    • Marchesini G, Brizi M, Bianchi G, et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001; 50: 1844-1850.
    • (2001) Diabetes , vol.50 , pp. 1844-1850
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3
  • 37
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43: S99-S112.
    • (2006) Hepatology , vol.43 , pp. S99-S112
    • Farrell, G.C.1    Larter, C.Z.2
  • 38
    • 0036829092 scopus 로고    scopus 로고
    • AGA technical review on nonalcoholic fatty liver disease
    • American Gastroenterological Association.
    • Sanyal AJ, American Gastroenterological Association. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002; 123: 1705-1725.
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
    • Sanyal, A.J.1
  • 39
    • 3042824524 scopus 로고    scopus 로고
    • Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
    • Feldstein AE, Werneburg NW, Canbay A, et al. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 2004; 40: 185-194.
    • (2004) Hepatology , vol.40 , pp. 185-194
    • Feldstein, A.E.1    Werneburg, N.W.2    Canbay, A.3
  • 40
    • 85030434746 scopus 로고    scopus 로고
    • Increased oxidative stress in obesity and its impact on metabolic syndrome
    • Furukawa S, Fujita T, Shimabukuro M, et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 2004; 114: 1752-1761.
    • (2004) J Clin Invest , vol.114 , pp. 1752-1761
    • Furukawa, S.1    Fujita, T.2    Shimabukuro, M.3
  • 41
    • 33644888156 scopus 로고    scopus 로고
    • Liver disease in patients with diabetes mellitus
    • Harrison SA. Liver disease in patients with diabetes mellitus. J Clin Gastroenterol 2006; 40: 68-76.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 68-76
    • Harrison, S.A.1
  • 42
    • 10844262508 scopus 로고    scopus 로고
    • Efficacy and effectiveness of liver screening program to detect fatty liver in the periodic health check-ups
    • Nomura K, Yano E, Shinozaki T, Tagawa K. Efficacy and effectiveness of liver screening program to detect fatty liver in the periodic health check-ups. J Occup Health 2004; 46: 423-428.
    • (2004) J Occup Health , vol.46 , pp. 423-428
    • Nomura, K.1    Yano, E.2    Shinozaki, T.3    Tagawa, K.4


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