메뉴 건너뛰기




Volumn 13, Issue 11, 2014, Pages 3138-3151

Down-regulation of ras-related protein rab 5C-dependent endocytosis and glycolysis in cisplatin-resistant ovarian cancer cell lines

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE 6 PHOSPHATE ISOMERASE; GLUTATHIONE REDUCTASE; HEAT SHOCK PROTEIN 90; LACTATE DEHYDROGENASE; LIPOCORTIN 1; LIPOCORTIN 2; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE KINASE 1; PYRUVATE KINASE; RAB 11B PROTEIN; RAB 5C PROTEIN; RAB PROTEIN; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VIMENTIN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ANXA2 PROTEIN, HUMAN; RAB5C PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84910635992     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M113.033217     Document Type: Article
Times cited : (41)

References (56)
  • 2
    • 66849114911 scopus 로고    scopus 로고
    • Phase ii evaluation of pemetrexed in the treatment of recurrent or persistent platinumresistant ovarian or primary peritoneal carcinoma: A study of the gynecologic oncology group
    • Miller, D. S., Blessing, J. A., Krasner, C. N., Mannel, R. S., Hanjani, P., Pearl, M. L., Waggoner, S. E., and Boardman, C. H. (2009) Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinumresistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group. J. Clin. Oncol. 27, 2686-2691
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2686-2691
    • Miller, D.S.1    Blessing, J.A.2    Krasner, C.N.3    Mannel, R.S.4    Hanjani, P.5    Pearl, M.L.6    Waggoner, S.E.7    Boardman, C.H.8
  • 4
    • 0023616968 scopus 로고
    • Multidrug resistance in ovarian cancer
    • Fojo, A., Hamilton, T. C., Young, R. C., and Ozols, R. F. (1987) Multidrug resistance in ovarian cancer. Cancer 60, 2075-2080
    • (1987) Cancer , vol.60 , pp. 2075-2080
    • Fojo, A.1    Hamilton, T.C.2    Young, R.C.3    Ozols, R.F.4
  • 5
    • 10644269449 scopus 로고    scopus 로고
    • Copper transporters regulate the cellular pharmacology and sensitivity to pt drugs
    • Safaei, R., and Howell, S. B. (2005) Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs. Crit. Rev. Oncol. Hemat. 53, 13-23
    • (2005) Crit. Rev. Oncol. Hemat. , vol.53 , pp. 13-23
    • Safaei, R.1    Howell, S.B.2
  • 6
    • 0037195066 scopus 로고    scopus 로고
    • Uptake of the anticancer drug cisplatin mediated by the copper transporter ctr1 in yeast and mammals
    • Ishida, S., Lee, J., Thiele, D. J., and Herskowitz, I. (2002) Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc. Natl. Acad. Sci. 99, 14298-14302
    • (2002) Proc. Natl. Acad. Sci. , vol.99 , pp. 14298-14302
    • Ishida, S.1    Lee, J.2    Thiele, D.J.3    Herskowitz, I.4
  • 8
    • 0036840625 scopus 로고    scopus 로고
    • The copper transporter ctr1 regulates cisplatin uptake in saccharomyces cerevisiae
    • Lin, X., Okuda, T., Holzer, A., and Howell, S. B. (2002) The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae. Mol. Pharmacol. 62, 1154-1159
    • (2002) Mol. Pharmacol. , vol.62 , pp. 1154-1159
    • Lin, X.1    Okuda, T.2    Holzer, A.3    Howell, S.B.4
  • 9
    • 4844224830 scopus 로고    scopus 로고
    • Cisplatin rapidly down-regulates its own influx transporter hctr1 in cultured human ovarian carcinoma cells
    • Holzer, A. K., Katano, K., Klomp, L. W., and Howell, S. B. (2004) Cisplatin rapidly down-regulates its own influx transporter hCTR1 in cultured human ovarian carcinoma cells. Clin. Cancer Res. 10, 6744-6749
    • (2014) Clin. Cancer Res. , vol.10 , pp. 6744-6749
    • Holzer, A.K.1    Katano, K.2    Klomp, L.W.3    Howell, S.B.4
  • 11
    • 0034792174 scopus 로고    scopus 로고
    • In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line
    • Cocker, H. A., Tiffin, N., Pritchard-Jones, K., Pinkerton, C. R., and Kelland, L. R. (2001) In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line. Clin. Cancer Res. 7, 3193-3198
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3193-3198
    • Cocker, H.A.1    Tiffin, N.2    Pritchard-Jones, K.3    Pinkerton, C.R.4    Kelland, L.R.5
  • 12
    • 0029555833 scopus 로고
    • P-glycoprotein expression in ovarian cancer cell line following treatment with cisplatin
    • Yang, X., and Page, M. (1995) P-glycoprotein expression in ovarian cancer cell line following treatment with cisplatin. Oncol. Res. 7, 619-624
    • (1995) Oncol. Res. , vol.7 , pp. 619-624
    • Yang, X.1    Page, M.2
  • 13
    • 84863826350 scopus 로고    scopus 로고
    • Resistance to paclitaxel in a cisplatin-resistant ovarian cancer cell line is mediated by p-glycoprotein
    • Stordal, B., Hamon, M., McEneaney, V., Roche, S., Gillet, J.-P., O'Leary, J. J., Gottesman, M., and Clynes, M. (2012) Resistance to paclitaxel in a cisplatin-resistant ovarian cancer cell line is mediated by P-glycoprotein. PLoS One 7, e40717
    • (2012) PLoS One , vol.7 , pp. e40717
    • Stordal, B.1    Hamon, M.2    McEneaney, V.3    Roche, S.4    Gillet, J.-P.5    O'Leary, J.J.6    Gottesman, M.7    Clynes, M.8
  • 14
    • 34547100275 scopus 로고    scopus 로고
    • The resurgence of platinum-based cancer chemotherapy
    • Kelland, L. (2007) The resurgence of platinum-based cancer chemotherapy. Nat. Rev. Cancer 7, 573-584
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 573-584
    • Kelland, L.1
  • 15
    • 0035750278 scopus 로고    scopus 로고
    • Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cdna microarray
    • Sakamoto, M., Kondo, A., Kawasaki, K., Goto, T., Sakamoto, H., Miyake, K., Koyamatsu, Y., Akiya, T., Iwabuchi, H., and Muroya, T. (2001) Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray. Human Cell 14, 305-315
    • (2001) Human Cell , vol.14 , pp. 305-315
    • Sakamoto, M.1    Kondo, A.2    Kawasaki, K.3    Goto, T.4    Sakamoto, H.5    Miyake, K.6    Koyamatsu, Y.7    Akiya, T.8    Iwabuchi, H.9    Muroya, T.10
  • 16
    • 68249159896 scopus 로고    scopus 로고
    • Integrated analysis of dna methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
    • Li, M., Balch, C., Montgomery, J. S., Jeong, M., Chung, J. H., Yan, P., Huang, T. H., Kim, S., and Nephew, K. P. (2009) Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. BMC Med. Genomics 2, 34
    • (2009) BMC Med. Genomics , vol.2 , pp. 34
    • Li, M.1    Balch, C.2    Montgomery, J.S.3    Jeong, M.4    Chung, J.H.5    Yan, P.6    Huang, T.H.7    Kim, S.8    Nephew, K.P.9
  • 17
    • 0026594392 scopus 로고
    • High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis
    • Godwin, A. K., Meister, A., O'Dwyer, P. J., Huang, C. S., Hamilton, T. C., and Anderson, M. E. (1992) High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc. Natl. Acad. Sci. 89, 3070-3074
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 3070-3074
    • Godwin, A.K.1    Meister, A.2    O'Dwyer, P.J.3    Huang, C.S.4    Hamilton, T.C.5    Anderson, M.E.6
  • 18
    • 33845629728 scopus 로고    scopus 로고
    • Characterization of a clonal isolate of an oxaliplatin resistant ovarian carcinoma cell line a2780/c10
    • Hector, S., Nava, M. E., Clark, K., Murphy, M., and Pendyala, L. (2007) Characterization of a clonal isolate of an oxaliplatin resistant ovarian carcinoma cell line A2780/C10. Cancer Lett. 245, 195-204
    • (2007) Cancer Lett. , vol.245 , pp. 195-204
    • Hector, S.1    Nava, M.E.2    Clark, K.3    Murphy, M.4    Pendyala, L.5
  • 19
    • 40949130371 scopus 로고    scopus 로고
    • Platinum resistance: The role of dna repair pathways
    • Martin, L. P., Hamilton, T. C., and Schilder, R. J. (2008) Platinum resistance: the role of DNA repair pathways. Clin. Cancer Res. 14, 1291-1295
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1291-1295
    • Martin, L.P.1    Hamilton, T.C.2    Schilder, R.J.3
  • 20
    • 0037444279 scopus 로고    scopus 로고
    • Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
    • Selvakumaran, M., Pisarcik, D. A., Bao, R., Yeung, A. T., and Hamilton, T. C. (2003) Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res. 63, 1311-1316
    • (2003) Cancer Res. , vol.63 , pp. 1311-1316
    • Selvakumaran, M.1    Pisarcik, D.A.2    Bao, R.3    Yeung, A.T.4    Hamilton, T.C.5
  • 21
    • 0028141961 scopus 로고
    • Messenger rna levels of xpac and ercc1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
    • Dabholkar, M., Vionnet, J., Bostick-Bruton, F., Yu, J. J., and Reed, E. (1994) Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J. Clin. Invest. 94, 703-708
    • (1994) J. Clin. Invest. , vol.94 , pp. 703-708
    • Dabholkar, M.1    Vionnet, J.2    Bostick-Bruton, F.3    Yu, J.J.4    Reed, E.5
  • 23
    • 80052035210 scopus 로고    scopus 로고
    • Frequency of mismatch repair deficiency in ovarian cancer: A systematic review
    • Murphy, M. A., and Wentzensen, N. (2011) Frequency of mismatch repair deficiency in ovarian cancer: a systematic review. Int. J. Cancer 129, 1914-1922
    • (2011) Int. J. Cancer , vol.129 , pp. 1914-1922
    • Murphy, M.A.1    Wentzensen, N.2
  • 26
    • 42349096328 scopus 로고    scopus 로고
    • Secondary brca1 mutations in brca1-mutated ovarian carcinomas with platinum resistance
    • Swisher, E. M., Sakai, W., Karlan, B. Y., Wurz, K., Urban, N., and Taniguchi, T. (2008) Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res. 68, 2581-2586
    • (2008) Cancer Res. , vol.68 , pp. 2581-2586
    • Swisher, E.M.1    Sakai, W.2    Karlan, B.Y.3    Wurz, K.4    Urban, N.5    Taniguchi, T.6
  • 27
    • 84867434999 scopus 로고    scopus 로고
    • Molecular determinants of ovarian cancer chemoresistance: New insights into an old conundrum
    • Ali, A. Y., Farrand, L., Kim, J. Y., Byun, S., Suh, J. Y., Lee, H. J., and Tsang, B. K. (2012) Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum. Ann. NY Acad. Sci. 1271, 58-67
    • (2012) Ann. NY Acad. Sci. , vol.1271 , pp. 58-67
    • Ali, A.Y.1    Farrand, L.2    Kim, J.Y.3    Byun, S.4    Suh, J.Y.5    Lee, H.J.6    Tsang, B.K.7
  • 28
    • 81355151361 scopus 로고    scopus 로고
    • Dna-pk mediates akt activation and apoptosis inhibition in clinically acquired platinum resistance
    • Stronach, E. A., Chen, M., Maginn, E. N., Agarwal, R., Mills, G. B., Wasan, H., and Gabra, H. (2011) DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance. Neoplasia 13, 1069-1080
    • (2011) Neoplasia , vol.13 , pp. 1069-1080
    • Stronach, E.A.1    Chen, M.2    Maginn, E.N.3    Agarwal, R.4    Mills, G.B.5    Wasan, H.6    Gabra, H.7
  • 30
    • 33847412362 scopus 로고    scopus 로고
    • Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines
    • Yan, X., Pan, L., Yuan, Y., Lang, J., and Mao, N. (2007) Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines. J. Proteome Res. 6, 772-780
    • (2007) J. Proteome Res. , vol.6 , pp. 772-780
    • Yan, X.1    Pan, L.2    Yuan, Y.3    Lang, J.4    Mao, N.5
  • 32
    • 78651283945 scopus 로고    scopus 로고
    • Proteomic analysis of cisplatin resistance in human ovarian cancer using 2-de method
    • Gong, F., Peng, X., Zeng, Z., Yu, M., Zhao, Y., and Tong, A. (2011) Proteomic analysis of cisplatin resistance in human ovarian cancer using 2-DE method. Mol. Cell. Biochem. 348, 141-147
    • (2011) Mol. Cell. Biochem. , vol.348 , pp. 141-147
    • Gong, F.1    Peng, X.2    Zeng, Z.3    Yu, M.4    Zhao, Y.5    Tong, A.6
  • 34
    • 33645463240 scopus 로고    scopus 로고
    • Proteins associated with cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mrna expression levels
    • Stewart, J. J., White, J. T., Yan, X., Collins, S., Drescher, C. W., Urban, N. D., Hood, L., and Lin, B. (2006) Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels. Mol. Cell. Proteomics 5, 433-443
    • (2006) Mol. Cell. Proteomics , vol.5 , pp. 433-443
    • Stewart, J.J.1    White, J.T.2    Yan, X.3    Collins, S.4    Drescher, C.W.5    Urban, N.D.6    Hood, L.7    Lin, B.8
  • 35
    • 65349153918 scopus 로고    scopus 로고
    • Comparative proteomic analysis of paclitaxel sensitive a2780 epithelial ovarian cancer cell line and its resistant counterpart a2780tc1 by 2d-dige: The role of erp57
    • Cicchillitti, L., Di Michele, M., Urbani, A., Ferlini, C., Donati, M. B., Scambia, G., and Rotilio, D. (2009) Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: the role of ERp57. J. Proteome Res. 8, 1902-1912
    • (2009) J. Proteome Res. , vol.8 , pp. 1902-1912
    • Cicchillitti, L.1    Di Michele, M.2    Urbani, A.3    Ferlini, C.4    Donati, M.B.5    Scambia, G.6    Rotilio, D.7
  • 36
    • 33750375542 scopus 로고    scopus 로고
    • Cisplatin preferentially binds mitochondrial dna and voltage-dependent anion channel protein in the mitochondrial membrane of head and neck squamous cell carcinoma: Possible role in apoptosis
    • Yang, Z., Schumaker, L. M., Egorin, M. J., Zuhowski, E. G., Guo, Z., and Cullen, K. J. (2006) Cisplatin preferentially binds mitochondrial DNA and voltage-dependent anion channel protein in the mitochondrial membrane of head and neck squamous cell carcinoma: possible role in apoptosis. Clin. Cancer Res. 12, 5817-5825
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5817-5825
    • Yang, Z.1    Schumaker, L.M.2    Egorin, M.J.3    Zuhowski, E.G.4    Guo, Z.5    Cullen, K.J.6
  • 37
    • 63149185244 scopus 로고    scopus 로고
    • Cisplatin impairs rat liver mitochondrial functions by inducing changes on membrane ion permeability: Prevention by thiol group protecting agents
    • Custódio, J., Cardoso, C. M., Santos, M. S., Almeida, L. M., Vicente, J. A., and Fernandes, M. A. (2009) Cisplatin impairs rat liver mitochondrial functions by inducing changes on membrane ion permeability: prevention by thiol group protecting agents. Toxicology 259, 18-24
    • (2009) Toxicology , vol.259 , pp. 18-24
    • Custódio, J.1    Cardoso, C.M.2    Santos, M.S.3    Almeida, L.M.4    Vicente, J.A.5    Fernandes, M.A.6
  • 39
    • 53349091778 scopus 로고    scopus 로고
    • Sirt1 contributes in part to cisplatin resistance in cancer cells by altering mitochondrial metabolism
    • Liang, X., Finkel, T., Shen, D., Yin, J., Aszalos, A., and Gottesman, M. M. (2008) SIRT1 contributes in part to cisplatin resistance in cancer cells by altering mitochondrial metabolism. Mol. Cancer Res, 6, 1499-1506
    • (2008) Mol. Cancer Res , vol.6 , pp. 1499-1506
    • Liang, X.1    Finkel, T.2    Shen, D.3    Yin, J.4    Aszalos, A.5    Gottesman, M.M.6
  • 40
    • 0026752490 scopus 로고
    • Mitochondrial defects in cisdiamminedichloroplatinum ii)-resistant human ovarian carcinoma cells
    • Andrews, P. A., and Albright, K. D. (1992) Mitochondrial defects in cisdiamminedichloroplatinum (II)-resistant human ovarian carcinoma cells. Cancer Res. 52, 1895-1901
    • (1992) Cancer Res. , vol.52 , pp. 1895-1901
    • Andrews, P.A.1    Albright, K.D.2
  • 41
    • 78049409468 scopus 로고    scopus 로고
    • Mitochondrial comparative proteomics of human ovarian cancer cells and their platinum-resistant sublines
    • Dai, Z., Yin, J., He, H., Li, W., Hou, C., Qian, X., Mao, N., and Pan, L. (2010) Mitochondrial comparative proteomics of human ovarian cancer cells and their platinum-resistant sublines. Proteomics 10, 3789-3799
    • (2010) Proteomics , vol.10 , pp. 3789-3799
    • Dai, Z.1    Yin, J.2    He, H.3    Li, W.4    Hou, C.5    Qian, X.6    Mao, N.7    Pan, L.8
  • 43
    • 33644770162 scopus 로고    scopus 로고
    • Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry
    • Minakata, K., Nozawa, H., Okamoto, N., and Suzuki, O. (2006) Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry. J. Chromatogr. B 832, 286-291
    • (2006) J. Chromatogr. B. , vol.832 , pp. 286-291
    • Minakata, K.1    Nozawa, H.2    Okamoto, N.3    Suzuki, O.4
  • 46
    • 84857171789 scopus 로고    scopus 로고
    • Pyruvate kinase m2: A key enzyme of the tumor metabolome and its medical relevance
    • Mazurek, S. (2012) Pyruvate kinase M2: a key enzyme of the tumor metabolome and its medical relevance. Biomedical Res. 23, 133-141
    • (2012) Biomedical Res. , vol.23 , pp. 133-141
    • Mazurek, S.1
  • 47
    • 12544256565 scopus 로고    scopus 로고
    • Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
    • Xu, R., Pelicano, H., Zhou, Y., Carew, J. S., Feng, L., Bhalla, K. N., Keating, M. J., and Huang, P. (2005) Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 65, 613-621
    • (2005) Cancer Res. , vol.65 , pp. 613-621
    • Xu, R.1    Pelicano, H.2    Zhou, Y.3    Carew, J.S.4    Feng, L.5    Bhalla, K.N.6    Keating, M.J.7    Huang, P.8
  • 48
    • 0035002230 scopus 로고    scopus 로고
    • Increased expression of peroxiredoxin ii confers resistance to cisplatin
    • Chung, Y., Yoo, Y., Park, J., Kim, Y., and Kim, H. J. (2000) Increased expression of peroxiredoxin II confers resistance to cisplatin. Anticancer Res. 21, 1129-1133
    • (2000) Anticancer Res. , vol.21 , pp. 1129-1133
    • Chung, Y.1    Yoo, Y.2    Park, J.3    Kim, Y.4    Kim, H.J.5
  • 49
    • 78650496816 scopus 로고    scopus 로고
    • Peroxiredoxin 6 overexpression attenuates cisplatin-induced apoptosis in human ovarian cancer cells
    • Pak, J. H., Choi, W. H., Lee, H. M., Joo, W.-D., Kim, J.-H., Kim, Y.-T., Kim, Y.-M., and Nam, J.-H. (2011) Peroxiredoxin 6 overexpression attenuates cisplatin-induced apoptosis in human ovarian cancer cells. Cancer Invest. 29, 21-28
    • (2011) Cancer Invest. , vol.29 , pp. 21-28
    • Pak, J.H.1    Choi, W.H.2    Lee, H.M.3    Joo, W.-D.4    Kim, J.-H.5    Kim, Y.-T.6    Kim, Y.-M.7    Nam, J.-H.8
  • 50
    • 80052267874 scopus 로고    scopus 로고
    • Vimentin in cancer and its potential as a molecular target for cancer therapy
    • Satelli, A., and Li, S. (2011) Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell. Mol. Life Sci. 68, 3033-3046
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 3033-3046
    • Satelli, A.1    Li, S.2
  • 51
    • 0242413674 scopus 로고    scopus 로고
    • Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations
    • Verrills, N. M., Walsh, B. J., Cobon, G. S., Hains, P. G., and Kavallaris, M. (2003) Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations. J. Biol. Chem. 278, 45082-45093
    • (2003) J. Biol. Chem. , vol.278 , pp. 45082-45093
    • Verrills, N.M.1    Walsh, B.J.2    Cobon, G.S.3    Hains, P.G.4    Kavallaris, M.5
  • 53
    • 84867872636 scopus 로고    scopus 로고
    • Acquired resistance to peloruside a and laulimalide is associated with down-regulation of vimentin in human ovarian carcinoma cells
    • Kanakkanthara, A., Rawson, P., Northcote, P. T., and Miller, J. H. (2012) Acquired resistance to Peloruside A and laulimalide is associated with down-regulation of vimentin in human ovarian carcinoma cells. Pharm. Res. 29, 3022-3032
    • (2012) Pharm. Res. , vol.29 , pp. 3022-3032
    • Kanakkanthara, A.1    Rawson, P.2    Northcote, P.T.3    Miller, J.H.4
  • 54
    • 67349143668 scopus 로고    scopus 로고
    • Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by fda
    • Arnesano, F., and Natile, G. (2009) Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA. Coordin. Chem. Rev. 253, 2070-2081
    • (2009) Coordin. Chem. Rev. , vol.253 , pp. 2070-2081
    • Arnesano, F.1    Natile, G.2
  • 55
    • 3843076458 scopus 로고    scopus 로고
    • Reduced expression of small gtpases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells
    • Shen, D., Su, A., Liang, X., Pai-Panandiker, A., and Gottesman, M. (2004) Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells. Br. J. Cancer 91, 270-276
    • (2004) Br. J. Cancer , vol.91 , pp. 270-276
    • Shen, D.1    Su, A.2    Liang, X.3    Pai-Panandiker, A.4    Gottesman, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.