HDAC4 promotes Pax7 -dependent satellite cell activation and muscle regeneration

EMBO Reports

Volumn 15, Issue 11, 2014, Pages 1175-1183

  Choi, Moon Chang ^a   Ryu, Soyoung ^a   Hao, Rui ^a   Wang, Bin ^a   Kapur, Meghan ^a   Fan, Chen Ming ^b   Yao, Tso Pang ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEOPHYSICAL LABORATORY   (United States)

Author keywords

HDAC4; Muscle regeneration; Pax7

Indexed keywords

CASPASE 3; HISTONE DEACETYLASE 4; MICRORNA; MICRORNA 133; MYOSIN HEAVY CHAIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PAX7; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HDAC5 PROTEIN, MOUSE; HISTONE DEACETYLASE; LIX1 PROTEIN, MOUSE; MIRN133 MICRORNA, MOUSE; PAX7 PROTEIN, MOUSE; PRDM16 PROTEIN, MOUSE; PROTEIN; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; LIPID STORAGE; MOUSE; MUSCLE INJURY; MUSCLE REGENERATION; NONHUMAN; PROTEIN EXPRESSION; RNA ANALYSIS; SATELLITE CELL; ANIMAL; CYTOLOGY; GENETICS; LIPID METABOLISM; METABOLISM; PHYSIOLOGY; REGENERATION; SKELETAL MUSCLE; SKELETAL MUSCLE SATELLITE CELL;

ANIMALS; CELL PROLIFERATION; DNA-BINDING PROTEINS; HISTONE DEACETYLASES; LIPID METABOLISM; MICE; MICRORNAS; MUSCLE, SKELETAL; PAX7 TRANSCRIPTION FACTOR; PROTEINS; REGENERATION; SATELLITE CELLS, SKELETAL MUSCLE; TRANSCRIPTION FACTORS;

EID: 84910144945     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201439195     Document Type: Article

References (25)

1. Bassel-Duby R, Olson EN (2006) Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem 75: 19-37
2. Choi MC, Cohen TJ, Barrientos T, Wang B, Li M, Simmons BJ, Yang JS, Cox GA, Zhao Y, Yao TP (2012) A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program. Mol Cell 47: 122-132
3. Cohen TJ, Waddell DS, Barrientos T, Lu Z, Feng G, Cox GA, Bodine SC, Yao TP (2007) The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. J Biol Chem 282: 33752-33759
4. Williams AH, Valdez G, Moresi V, Qi X, McAnally J, Elliott JL, Bassel-Duby R, Sanes JR, Olson EN (2009) MicroRNA- 206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 326: 1549-1554
5. Moresi V, Williams AH, Meadows E, Flynn JM, Potthoff MJ, McAnally J, Shelton JM, Backs J, Klein WH, Richardson JA et al (2010) Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell 143: 35-45
6. Lepper C, Partridge TA, Fan CM (2011) An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development 138: 3639-3646
7. Sambasivan R, Yao R, Kissenpfennig A, Van Wittenberghe L, Paldi A, Gayraud-Morel B, Guenou H, Malissen B, Tajbakhsh S, Galy A (2011) Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development 138: 3647-3656
8. Seale P, Sabourin LA, Girgis-Gabardo A, Mansouri A, Gruss P, Rudnicki MA (2000) Pax7 is required for the specification of myogenic satellite cells. Cell 102: 777-786
9. von Maltzahn J, Jones AE, Parks RJ, Rudnicki MA (2013) Pax7 is critical for the normal function of satellite cells in adult skeletal muscle. Proc Natl Acad Sci USA 110: 16474-16479
10. Gunther S, Kim J, Kostin S, Lepper C, Fan CM, Braun T (2013) Myf5-positive satellite cells contribute to Pax7-dependent long-term maintenance of adult muscle stem cells. Cell Stem Cell 13: 590-601
11. Oustanina S, Hause G, Braun T (2004) Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification. EMBO J 23: 3430-3439
12. Vettor R, Milan G, Franzin C, Sanna M, De Coppi P, Rizzuto R, Federspil G (2009) The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 297: E987-E998
13. Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scime A, Devarakonda S, Conroe HM, Erdjument-Bromage H et al (2008) PRDM16 controls a brown fat/skeletal muscle switch. Nature 454: 961-967
14. Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F et al (2013) MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab 17: 210-224
15. Simmons BJ, Cohen TJ, Bedlack R, Yao TP (2011) HDACs in skeletal muscle remodeling and neuromuscular disease. Handb Exp Pharmacol 206: 79-101
16. Nishijo K, Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP et al (2009) Biomarker system for studying muscle, stem cells, and cancer in vivo. FASEB J 23: 2681-2690
17. McKinnell IW, Ishibashi J, Le Grand F, Punch VG, Addicks GC, Greenblatt JF, Dilworth FJ, Rudnicki MA (2008) Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. Nat Cell Biol 10: 77-84
18. Kumar D, Shadrach JL, Wagers AJ, Lassar AB (2009) Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells. Mol Biol Cell 20: 3170-3177
19. Diao Y, Guo X, Li Y, Sun K, Lu L, Jiang L, Fu X, Zhu H, Sun H, Wang H et al (2012) Pax 3/7 BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Cell Stem Cell 11: 231-241
20. Trajkovski M, Ahmed K, Esau CC, Stoffel M (2012 ) MyomiR-133 regulates brown fat differentiation through Prdm16. Nat Cell Biol 14: 1330-1335
21. Liu W, Bi P, Shan T, Yang X, Yin H, Wang YX, Liu N, Rudnicki MA, Kuang S (2013) miR-133a regulates adipocyte browning in vivo. PLoS Genet 9: e1003626
22. Chen JF, Tao Y, Li J, Deng Z, Yan Z, Xiao X, Wang DZ (2010) microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol 190: 867-879
23. Zhang C, Li Y, Wu Y, Wang L, Wang X, Du J (2013) Interleukin-6/signal transducer and activator of transcription 3 (STAT3) pathway is essential for macrophage infiltration and myoblast proliferation during muscle regeneration. J Biol Chem 288: 1489-1499
24. Mao Y, Kucuk B, Irvine KD (2009) Drosophila lowfat, a novel modulator of fat signaling. Development 136: 3223-3233
25. Le Grand F, Jones AE, Seale V, Scime A, Rudnicki MA (2009) Wnt7 a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell 4: 535-547