Anti-inflammatory action of γ-irradiated genistein in murine peritoneal macrophage

Radiation Physics and Chemistry

Volumn 105, Issue , 2014, Pages 17-21

  Sung, Nak Yun ^a   Byun, Eui Baek ^a   Song, Du Sup ^a   Jin, Yeung Bae ^b   Park, Jae Nam ^a   Kim, Jae Kyung ^a   Park, Jong Heum ^a   Song, Beom Seok ^a   Park, Sang Hyun ^a   Lee, Ju Woon ^a   Kim, Jae Hun ^a  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Anti inflammatory activity; Cytokine; Cytotoxicity; Gamma irradiation; Genistein

Indexed keywords

ANTI-INFLAMMATORY ACTION; ANTI-INFLAMMATORY ACTIVITY; CYTOKINES; GAMMA IRRADIATION; GENISTEIN; MURINE PERITONEAL MACROPHAGES;

CYTOTOXICITY;

GENISTEIN; INTERLEUKIN 6; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; FEMALE; GAMMA RADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; RADIATION DOSE; STRUCTURE ANALYSIS;

EID: 84910101125     PISSN: 0969806X     EISSN: 18790895     Source Type: Journal    
DOI: 10.1016/j.radphyschem.2014.05.029     Document Type: Article

References (29)

1. Bertok L. Radio-detoxified endotoxin activates natural immunity: a review. Pathophysiology 2005, 12:85-95.
2. Bonkovsky H.L. Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis). Ann. Intern. Med. 2006, 144:68-71.
3. Byun E.B., Sung N.Y., Kim J.H., Choi J., Matsui T., Byunc M.W., Lee J.W. Enhancement of anti-tumor activity of gamma-irradiated silk fibroin via immunomodulatory effects. Chem. Biol. Interact. 2010, 186:90-95.
4. Byun E.B., Sung N.Y., Kwon S.K., Song B.S., Kim J.H., Choi J., Hwang H.J., Byun M.W., Lee J.W. in vitro and in vivo studies on the cytotoxicity of irradiated silk fibroin against mouse melanoma tumor cell. Radiat. Phys. Chem. 2009, 78:429-431.
5. Chang Y.C., Li P.C., Chen B.C., Chang M.S., Wang J.L., Chiu W.T., Lin C.H. Lipoteichoic acid-induced nitric oxide synthase expression in RAW 264.7 macrophages is mediated by cyclooxygenase-2, prostaglandin E2, protein kinase A, p38 MAPK, and nuclear factor-κB pathways. Cell. Signalling 2006, 18:1235-1243.
6. Choi J., Kim H.J. Preparation of low molecular weight fucoidan by gamma-irradiation and its anticancer activity. Carbohydr. Polym. 2013, 97:358-362.
7. Curtis C.L., Harwood J.L., Dent C.M., Caterson B. Biological basis for the benefit of nutraceutical supplementation in arthritis. Drug Discovery Today 2004, 9:165-172.
8. Duan W., Kuo I.C., Selvarajan S., Chua K.Y., Bay B.H., Wong W.S. Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma. Am. J. Respir. Crit. Care Med. 2003, 167:185-192.
9. Eigler A., Sinha B., Hartmann G., Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunology 1997, 18:487-492.
10. Elenkov I.J., Chrousos G.P. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann. N.Y. Acad. Sci. 2002, 966:290-303.
11. Farina H.G., Pomies M., Alonso D.F., Gomez D.E. Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer. Oncol. Rep. 2006, 16:885-891.
12. Hämäläinen M., Nieminen R., Vuorela P., Heinonen M., Moilanen E. Anti-inflammatory effect of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediators Inflamm. 2007, 2007:45673.
13. Hibbs J.B., Taintor R.R., Vavrin Z. Macrophage cytotoxicity: role for l-arginine deiminase and imino nitrogen oxidation to nitrite. Science 1987, 235:473-476.
14. Isbrucker R.A., Edwards J.A., Wolz E., Davidovich A., Bausch J. Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: Dermal, acute and short-term toxicity studies. Food Chem. Toxicol. 2005, 44:636-650.
15. Jung H.J., Park H.R., Jung U., Jo S.K. Radiolysis study of genistein in methanolic solution. Radiat. Phys. Chem. 2009, 78:386-393.
16. Kao T.H., Wu W.M., Hung C.F., Wu W.B., Chen B.H. Anti-inflammatory effects of isoflavone powder produced from soybean cake. J. Agric. Food Chem. 2007, 55:11068-11079.
17. Kraatz J., Clair L., Rodriguez J.L., Michael A. West macrophage TNF secretion in endotoxin tolerance: role of SAPK, p38, and MAPK. J. Surg. Res. 1999, 83:158-164.
18. Lambert J.D., Hong J., Yang G.Y., Liao J., Yang C.S. Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations. Am. J. Clin. Nutr. 2005, 81:284S-291S.
19. Lee S.L., Lee M.S., Song K.B. Effect of gamma-irradiation on the physicochemical properties of gluten films. Food Chem. 2005, 92:621-625.
20. MacMicking J., Xie Q.W., Nathan C. Nitric oxide and macrophage function. Annu. Rev. Immunol. 1997, 15:323-350.
21. Marfak A., Trouillas P., Allais D.P., Calliste C.A., Cook-Moreau J., Durouxa J.L. Reactivity of flavonoids with 1-hydroxyethyl radical: a g-radiolysis study. Biochim. Biophys. Acta 2004, 1670:28-39.
22. Ohkubo K., Ikeda M., Pawankar R., Gotoh M., Yagi T., Okuda M. Mechanisms of IL-6, IL-8, and GM-CSF release in nasal secretions of allergic patients after nasal challenge. Rhinology 1998, 36:156-161.
23. Palmer R.M., Ashton D.S., Moncada S. Vascular endothelial cells synthesize nitric oxide from l-arginine. Nature 1988, 333:664-666.
24. Rietschel E.T., Brade H. Bacterial endotoxins. Sci. Am. 1992, 267:54-61.
25. Sasamura H., Takahashi A., Yuan J., Kitamura H., Masumori N., Miyao N., Itoh N., Tsukamoto T. Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma. Urology 2004, 64:389-393.
26. Sheu F., Lai H.H., Yen G.C. Suppression effect of soy isoflavones on nitric oxide production in RAW 264.7 macrophages. J. Agric. Food Chem. 2001, 49:1767-1772.
27. Thomas P. Radiation preservation of foods of plant origins. Part VI: Mushrooms, tomatoes, minor fruits and vegetables, dried fruits and nuts. CRC Crit. Rev. Food Sci. Nutr. 1998, 26:313-358.
28. Weckmann A.L., Alcocer-Varela J. Cytokine inhibitors in autoimmune disease. Semin. Arthritis Rheum. 1996, 26:539-557.
29. Zhanga X.Y., Lib W.G., Wub Y.J., Zhenga T.Z., Lia W., Qu S.Y., Liu N.F. Proanthocyanidin from grape seeds potentiates anti-tumor activity of doxorubicin via immunomodulatory mechanism. Int. Immunopharmacol. 2005, 5:1247-1257.