A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Duan, Zhenfeng ^a   Zhang, Jianming ^a   Ye, Shunan ^a   Shen, Jacson ^a   Choy, Edwin ^a   Cote, Gregory ^a   Harmon, David ^a   Mankin, Henry ^a   Hua, Yingqi ^b   Zhang, Yu ^c   Gray, Nathanael S ^d   Hornicek, Francis J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c Liu Hua Qiao Hospital   (China)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Doxorubicin; MDR; Osteosarcoma; Src kinase

Indexed keywords

A 770041; DOXORUBICIN; PACLITAXEL; PROTEIN TYROSINE KINASE INHIBITOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; 1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID (4-(1-(4-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-AMINO-1H-PYRAZOLO(3,4-D)PYRIMIDIN-3-YL)-2-METHOXYPHENYL)AMIDE; ANTINEOPLASTIC AGENT; PEPTIDE LIBRARY; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SENSITIVITY; DRUG STRUCTURE; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL LINE; PROTEIN EXPRESSION; WESTERN BLOTTING; BONE NEOPLASMS; DRUG EFFECTS; DRUG POTENTIATION; DRUG RESISTANCE; GENE EXPRESSION REGULATION; METABOLISM; MULTIDRUG RESISTANCE; OSTEOSARCOMA; PEPTIDE LIBRARY; TUMOR CELL LINE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE NEOPLASMS; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; OSTEOSARCOMA; PACLITAXEL; PEPTIDE LIBRARY; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIMIDINES; SRC-FAMILY KINASES;

EID: 84910075077     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-681     Document Type: Article

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