Expression and prognostic value of estrogen receptor beta in breast cancer patients

International Journal of Clinical and Experimental Medicine

Volumn 7, Issue 10, 2014, Pages 3730-3736

  Guo, Liying ^a   Zhu, Qianwen ^a   Yilamu, Dilimina ^a   Jakulin, Adina ^a   Liu, Sha ^a   Liang, Ting ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; ER ; Prognosis

Indexed keywords

ANTHRACYCLINE; ESTROGEN RECEPTOR BETA; PACLITAXEL;

ADULT; AGED; ARTICLE; BREAST CANCER; BREAST METASTASIS; CANCER GRADING; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CELL COUNT; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LOG RANK TEST; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MEDICAL RECORD; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; TELEPHONE; TUMOR VOLUME;

EID: 84910074463     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Idelman G, Jacobson EM, Tuttle TR, Ben-Jonathan N. Lactogens and estrogens in breast cancer chemoresistance. Expert Rev Endocrinol Metab 2011; 6: 411-422.
2. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA. Cloning of a novel receptor expressed in rat prostate and ovary. Proe Natl A cad Sci U S A 1996; 93: 5925-5930.
3. Hou YF, Yuan ST, Li HC, Wu J, Lu JS, Liu G, Lu LJ, Shen ZZ, Ding J, Shao ZM. Erbeta exerts multiple stimulative effects on human breast carcinoma eclls. Oncogene 2004; 23: 5799-5806.
4. Knowlden JM, Gee JM, Robertson JF, Ellis IO, Nicholson RI. A possible divergent role for the oestrogen receptor alpha and beta subtypes in clinical breast cancer. Int J Cancer 2000; 89: 209-212.
5. Wu W, Lv XH, Tang ZH. Expression of ERl3 mRNA and the VEGF mRNA in breast cancer tissue and the relationship between them. Chinese Journal of General Surgery 2006; 15: 741-744.
6. Speirs V, Carder PJ, Lane S, Dodwell D, Lansdown MR, Hanby AM. Oestrogen receptor beta: what it means for patients with breast cancer. Lancet Oncol 2004; 5: 174-181.
7. Ström A, Hartman J, Foster JS, Kietz S, Wimalasena J, Gustafsson JA. Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc Natl Acad Sci U S A 2004; 101: 1566-1571.
8. Nilsson S, Gustafsson JÅ. Estrogen receptors: therapies targeted to receptor subtypes. Clin Pharmacol Ther 2011; 89: 44-55.
9. Nakopoulou L, Lazaris AC, Panayotopoulou EG, Giannopoulou I, Givalos N, Markaki S, Keramopoulos A. The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer. J Clin Pathol 2004; 57: 523-528.
10. Jensen EV, Jordan VC. The estrogen receptor: a model for molecular medicine. Clin Cancer Res 2003; 9: 1980-1989.
11. Speirs V, Parkes AT, Kerin MJ, Walton DS, Carleton PJ, Fox JN, Atkin SL. Coexpression of estrogen receptor α and β: poor prognostic factors in human breast cancer? Cancer Res 1999; 59: 525-528.
12. Miyoshi Y, Taguchi T, Gustafsson JA, Noguchi S. Clinicopathological characteristics of estrogen receptor-beta-positive human breast cancer. Jpn J Cancer Res 2001; 92: 1057-1061.
13. Järvinen TA, Pelto-Huikko M, Holli K, Isola J. Estrogen receptor beta ia coexpressed with Eralpha and PR and associated with nodal status, grade, and proliferation rate in breast cancer. Am J Pathol 2000; 156: 29-35.
14. Skliris GP, Munot K, Bell SM, Carder PJ, Lane S, Horgan K, Lansdown MR, Parkes AT, Hanby AM, Markham AF, Speirs V. Reduced expression of oesrogen receptor β in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol 2003; 201: 213-220.
15. Vinayagam R, Sibson DR, Holcombe C, Aachi V, Davies MP. Association of oestrogen receptor beta 2 (ER beta2/ER beta cx) with outcome of adjuvant endocrine treatment for primary breast caner-a retrospective study. BMC Cancer 2007; 7: 131.