Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats

Particle and Fibre Toxicology

Volumn 11, Issue 1, 2014, Pages

  Erdely, Aaron ^a,c   Antonini, James M ^a   Young, Shih Houng ^b   Kashon, Michael L ^a   Gu, Ja K ^a   Hulderman, Tracy ^a   Salmen, Rebecca ^a   Meighan, Terence ^a   Roberts, Jenny R ^a   Zeidler Erdely, Patti C ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b US Army Institute of Public Health   (United States)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Cardiovascular disease; Chromium; Immunosuppression; Microarray; Welding; Whole blood cell gene expression

Indexed keywords

CXCL2 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; PHOSPHATE BUFFERED SALINE; STAINLESS STEEL; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; PARTICULATE MATTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CELL ISOLATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNE RESPONSE; LEUKOCYTE ACTIVATION; LEUKOCYTE DIFFERENTIAL COUNT; LEUKOCYTE DISORDER; LEUKOCYTE FUNCTION; MICROARRAY ANALYSIS; MONONUCLEAR CELL; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RNA ISOLATION; WELDING FUME; ADVERSE EFFECTS; ANIMAL; CELL CULTURE; DNA MICROARRAY; DRUG EFFECTS; EXPOSURE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; LEUKOCYTE; MALE; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT; TIME; TOXICITY; WELDING;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOCOMPROMISED HOST; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; LEUKOCYTES; LIPOPOLYSACCHARIDES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PARTICULATE MATTER; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STAINLESS STEEL; TIME FACTORS; TRANSCRIPTION, GENETIC; WELDING;

EID: 84910058772     PISSN: 17438977     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/s12989-014-0034-8     Document Type: Article

References (33)

1. Zeidler-Erdely PC, Erdely A, Antonini JM. Immunotoxicology of arc welding fume: worker and experimental animal studies. J Immunotoxicol 2012, 9:411-425. 10.3109/1547691X.2011.652783.
2. Palmer KT, Cosgrove MP. Vaccinating welders against pneumonia. Occup Med (Lond) 2012, 62:325-330. 10.1093/occmed/kqs055.
3. Antonini JM, Roberts JR, Stone S, Chen BT, Schwegler-Berry D, Frazer DG. Short-Term Inhalation Exposure to Mild Steel Welding Fume had no Effect on Lung Inflammation and Injury but did Alter Defense Responses to Bacteria in Rats. Inhal Toxicol 2009, 21:182-192. 10.1080/08958370802360661.
4. Antonini JM, Stone S, Roberts JR, Chen B, Schwegler-Berry D, Afshari AA, Frazer DG. Effect of short-term stainless steel welding fume inhalation exposure on lung inflammation, injury, and defense responses in rats. Toxicol Appl Pharmacol 2007, 223:234-245. 10.1016/j.taap.2007.06.020.
5. Antonini JM, Taylor MD, Millecchia L, Bebout AR, Roberts JR. Suppression in lung defense responses after bacterial infection in rats pretreated with different welding fumes. Toxicol Appl Pharmacol 2004, 200:206-218. 10.1016/j.taap.2004.04.022.
6. Anderson SE, Meade BJ, Butterworth LF, Munson AE. The humoral immune response of mice exposed to manual metal arc stainless steel-welding fumes. J Immunotoxicol 2007, 4:15-23. 10.1080/15476910601115119.
7. Erdely A, Hulderman T, Salmen R, Liston A, Zeidler-Erdely PC, Schwegler-Berry D, Castranova V, Koyama S, Kim YA, Endo M, Simeonova PP. Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers. Nano Lett 2009, 9:36-43. 10.1021/nl801828z.
8. du Plessis L, Laubscher P, Jooste J, du Plessis J, Franken A, van Aarde N, Eloff F. Flow cytometric analysis of the oxidative status in human peripheral blood mononuclear cells of workers exposed to welding fumes. J Occup Environ Hyg 2010, 7:367-374. 10.1080/15459621003724108.
9. Cohn CA, Simon SR, Schoonen MA. Comparison of fluorescence-based techniques for the quantification of particle-induced hydroxyl radicals. Part Fibre Toxicol 2008, 5:2. 10.1186/1743-8977-5-2.
10. Shenton D, Smirnova JB, Selley JN, Carroll K, Hubbard SJ, Pavitt GD, Ashe MP, Grant CM. Global translational responses to oxidative stress impact upon multiple levels of protein synthesis. J Biol Chem 2006, 281:29011-29021. 10.1074/jbc.M601545200.
11. Di Matteo MA, Loweth AC, Thomas S, Mabley JG, Morgan NG, Thorpe JR, Green IC. Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms. Apoptosis 1997, 2:164-177. 10.1023/A:1026412414666.
12. Antonini JM, Roberts JR, Jernigan MR, Yang HM, Ma JY, Clarke RW. Residual oil fly ash increases the susceptibility to infection and severely damages the lungs after pulmonary challenge with a bacterial pathogen. Toxicol Sci 2002, 70:110-119. 10.1093/toxsci/70.1.110.
13. Cohen MD. Pulmonary immunotoxicology of select metals: aluminum, arsenic, cadmium, chromium, copper, manganese, nickel, vanadium, and zinc. J Immunotoxicol 2004, 1:39-69. 10.1080/15476910490438360.
14. Cohen MD, Zelikoff JT, Chen LC, Schlesinger RB. Immunotoxicologic effects of inhaled chromium: role of particle solubility and co-exposure to ozone. Toxicol Appl Pharmacol 1998, 152:30-40. 10.1006/taap.1998.8502.
15. Coggon D, Inskip H, Winter P, Pannett B. Lobar pneumonia: an occupational disease in welders. Lancet 1994, 344:41-43. 10.1016/S0140-6736(94)91056-1.
16. Palmer KT, Poole J, Ayres JG, Mann J, Burge PS, Coggon D. Exposure to metal fume and infectious pneumonia. Am J Epidemiol 2003, 157:227-233. 10.1093/aje/kwf188.
17. Antonini JM, Leonard SS, Roberts JR, Solano-Lopez C, Young SH, Shi X, Taylor MD. Effect of stainless steel manual metal arc welding fume on free radical production, DNA damage, and apoptosis induction. Mol Cell Biochem 2005, 279:17-23. 10.1007/s11010-005-8211-6.
18. Taylor MD, Roberts JR, Leonard SS, Shi XL, Antonini JM. Effects of welding fumes of differing composition and solubility on free radical production and acute lung injury and inflammation in rats. Toxicol Sci 2003, 75:181-191. 10.1093/toxsci/kfg173.
19. Erdely A, Salmen-Muniz R, Liston A, Hulderman T, Zeidler-Erdely PC, Antonini JM, Simeonova PP. Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matter. Toxicology 2011, 287:153-159. 10.1016/j.tox.2011.06.008.
20. Antonini JM, Roberts JR. Chromium in stainless steel welding fume suppresses lung defense responses against bacterial infection in rats. J Immunotoxicol 2007, 4:117-127. 10.1080/15476910701336953.
21. Goulart M, Batoreu MC, Rodrigues AS, Laires A, Rueff J. Lipoperoxidation products and thiol antioxidants in chromium exposed workers. Mutagenesis 2005, 20:311-315. 10.1093/mutage/gei043.
22. Sorensen M, Schins RP, Hertel O, Loft S. Transition metals in personal samples of PM2.5 and oxidative stress in human volunteers. Cancer Epidemiol Biomarkers Prev 2005, 14:1340-1343. 10.1158/1055-9965.EPI-04-0899.
23. Patlolla AK, Barnes C, Yedjou C, Velma VR, Tchounwou PB. Oxidative stress, DNA damage, and antioxidant enzyme activity induced by hexavalent chromium in Sprague-Dawley rats. Environ Toxicol 2009, 24:66-73. 10.1002/tox.20395.
24. Erdely A, Liston A, Salmen-Muniz R, Hulderman T, Young SH, Zeidler-Erdely PC, Castranova V, Simeonova PP. Identification of systemic markers from a pulmonary carbon nanotube exposure. J Occup Environ Med 2011, 53:S80-S86. 10.1097/JOM.0b013e31821ad724.
25. Talwar S, Munson PJ, Barb J, Fiuza C, Cintron AP, Logun C, Tropea M, Khan S, Reda D, Shelhamer JH, Danner RL, Suffredini AF. Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans. Physiol Genomics 2006, 25:203-215. 10.1152/physiolgenomics.00192.2005.
26. Erdely A, Hulderman T, Salmen-Muniz R, Liston A, Zeidler-Erdely PC, Chen BT, Stone S, Frazer DG, Antonini JM, Simeonova PP. Inhalation exposure of gas-metal arc stainless steel welding fume increased atherosclerotic lesions in apolipoprotein E knockout mice. Toxicol Lett 2011, 204:12-16. 10.1016/j.toxlet.2011.03.030.
27. Fang SC, Eisen EA, Cavallari JM, Mittleman MA, Christiani DC. Acute changes in vascular function among welders exposed to metal-rich particulate matter. Epidemiology 2008, 19:217-225. 10.1097/EDE.0b013e31816334dc.
28. Kim JY, Chen JC, Boyce PD, Christiani DC. Exposure to welding fumes is associated with acute systemic inflammatory responses. Occup Environ Med 2005, 62:157-163. 10.1136/oem.2004.014795.
29. Nurkiewicz TR, Porter DW, Barger M, Millecchia L, Rao KM, Marvar PJ, Hubbs AF, Castranova V, Boegehold MA. Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure. Environ Health Perspect 2006, 114:412-419. 10.1289/ehp.8413.
30. Antonini JM, Lawryk NJ, Murthy GGK, Brain JD. Effect of welding fume solubility on lung macrophage viability and function in vitro. J Toxicol Environ Health A 1999, 58:343-363. 10.1080/009841099157205.
31. Antonini JM, Zeidler-Erdely PC, Young SH, Roberts JR, Erdely A. Systemic immune cell response in rats after pulmonary exposure to manganese-containing particles collected from welding aerosols. J Immunotoxicol 2012, 9:184-192. 10.3109/1547691X.2011.650733.
32. Erdely A, Antonini JM, Salmen-Muniz R, Liston A, Hulderman T, Simeonova PP, Kashon ML, Li S, Gu JK, Stone S, Chen BT, Frazer DG, Zeidler-Erdely PC. Type I interferon and pattern recognition receptor signaling following particulate matter inhalation. Part Fibre Toxicol 2012, 9:25. 10.1186/1743-8977-9-25.
33. Zeidler-Erdely PC, Kashon ML, Li S, Antonini JM. Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice. Respir Res 2010, 11:70. 10.1186/1465-9921-11-70.