Response of the mouse lung transcriptome to welding fume: Effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice

Respiratory Research

Volumn 11, Issue , 2010, Pages

  Zeidler Erdely, Patti C ^a   Kashon, Michael L ^a   Li, Shengqiao ^a   Antonini, James M ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN A; CALGRANULIN B; CARBON TETRACHLORIDE; CHEMOTACTIC PEPTIDE; CHROMIUM; CXCL2 CHEMOKINE; GELATINASE B; MACROPHAGE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NICKEL; STAINLESS STEEL; TRANSCRIPTOME; STEEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SUSCEPTIBILITY; CELL MOTILITY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GENE CONTROL; GENE EXPRESSION; IMMUNE RESPONSE; INFLAMMATION; LUNG CANCER; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; UPREGULATION; WELDING FUME; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CLUSTER ANALYSIS; COMPARATIVE STUDY; CONVALESCENCE; DNA MICROARRAY; DRUG EFFECT; EXPOSURE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LUNG; LUNG TUMOR; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; PNEUMONIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOKE; SPECIES DIFFERENCE; TIME; WELDING;

ANIMALS; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; INHALATION EXPOSURE; LUNG; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PNEUMONIA; RECOVERY OF FUNCTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMOKE; SPECIES SPECIFICITY; STAINLESS STEEL; STEEL; TIME FACTORS; WELDING;

EID: 77956654469     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-11-70     Document Type: Article

References (34)

1. Danielsen TE, Langard S, Andersen A. Incidence of lung cancer among shipyard welders investigated for siderosis. Int J Occup Environ Health 1998, 4(2):85-88.
2. Moulin JJ. A meta-analysis of epidemiologic studies of lung cancer in welders. Scand J Work Environ Health 1997, 23(2):104-113.
3. Sorensen AR, Thulstrup AM, Hansen J, Ramlau-Hansen CH, Meersohn A, Skytthe A, Bonde JP. Risk of lung cancer according to mild steel and stainless steel welding. Scand J Work Environ Health 2007, 33(5):379-386.
4. Sferlazza SJ, Beckett WS. The respiratory health of welders. Am Rev Respir Dis 1991, 143(5 Pt 1):1134-1148.
5. Lauritsen JM, Hansen KS. Lung cancer mortality in stainless steel and mild steel welders: a nested case-referent study. Am J Ind Med 1996, 30(4):383-391. 10.1002/(SICI)1097-0274(199610)30:4<383::AID-AJIM2>3.0.CO;2-X, 8892542.
6. Steenland K. Ten-year update on mortality among mild-steel welders. Scand J Work Environ Health 2002, 28(3):163-167.
7. IARC Chromium, nickel and welding. IARC Monogr Eval Carcinog Risks Hum 1990, 49:1-648. IARC.
8. Shimkin MB, Stoner GD. Lung tumors in mice: application to carcinogenesis bioassay. Adv Cancer Res 1975, 21:1-58. full_text, 1108612.
9. Zeidler-Erdely PC, Kashon ML, Battelli LA, Young SH, Erdely A, Roberts JR, Reynolds SH, Antonini JM. Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume. Particle and fibre toxicology 2008, 5:12. 10.1186/1743-8977-5-12, 2546436, 18778475.
10. Antonini JM, Lewis AB, Roberts JR, Whaley DA. Pulmonary effects of welding fumes: review of worker and experimental animal studies. Am J Ind Med 2003, 43(4):350-360. 10.1002/ajim.10194, 12645092.
11. Taylor MD, Roberts JR, Leonard SS, Shi X, Antonini JM. Effects of welding fumes of differing composition and solubility on free radical production and acute lung injury and inflammation in rats. Toxicol Sci 2003, 75(1):181-191. 10.1093/toxsci/kfg173, 12832661.
12. Oh JH, Yang MJ, Yang YS, Park HJ, Heo SH, Lee EH, Song CW, Yoon S. Microarray-based analysis of the lung recovery process after stainless-steel welding fume exposure in Sprague-Dawley rats. Inhal Toxicol 2009, 21(4):347-373. 10.1080/08958370802464281, 19235613.
13. Heo JD, Oh JH, Lee K, Kim CY, Song CW, Yoon S, Han JS, Yu IJ. Gene expression profiling in the lung tissue of cynomolgus monkeys in response to repeated exposure to welding fumes. Arch Toxicol 2009, 2820669, 19936710.
14. Antonini JM, Lawryk NJ, Murthy GG, Brain JD. Effect of welding fume solubility on lung macrophage viability and function in vitro. J Toxicol Environ Health A 1999, 58(6):343-363. 10.1080/009841099157205, 10580758.
15. Rao GV, Tinkle S, Weissman DN, Antonini JM, Kashon ML, Salmen R, Battelli LA, Willard PA, Hoover MD, Hubbs AF. Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx. J Toxicol Environ Health A 2003, 66(15):1441-1452. 10.1080/15287390306417, 12857634.
16. Solano-Lopez C, Zeidler-Erdely PC, Hubbs AF, Reynolds SH, Roberts JR, Taylor MD, Young SH, Castranova V, Antonini JM. Welding Fume Exposure and Associated Inflammatory and Hyperplastic Changes in the Lungs of Tumor Susceptible A/J Mice. Toxicol Pathol 2006, 34(4):364-372. 10.1080/01926230600815122, 16844664.
17. Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002, 30(1):207-210. 10.1093/nar/30.1.207, 99122, 11752295.
18. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004, 5(10):R80. 10.1186/gb-2004-5-10-r80, 545600, 15461798.
19. Lin SM, Du P, Huber W, Kibbe WA. Model-based variance-stabilizing transformation for Illumina microarray data. Nucleic Acids Res 2008, 36(2):e11. 10.1093/nar/gkm1075, 2241869, 18178591.
20. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408. 10.1006/meth.2001.1262, 11846609.
21. Vasu VT, Cross CE, Gohil K. Nr1d1, an important circadian pathway regulatory gene, is suppressed by cigarette smoke in murine lungs. Integr Cancer Ther 2009, 8(4):321-328. 10.1177/1534735409352027, 2837720, 19926613.
22. Fu L, Lee CC. The circadian clock: pacemaker and tumour suppressor. Nat Rev Cancer 2003, 3(5):350-361. 10.1038/nrc1072, 12724733.
23. Downes M, Carozzi AJ, Muscat GE. Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family. Mol Endocrinol 1995, 9(12):1666-1678. 10.1210/me.9.12.1666, 8614403.
24. Chawla A, Lazar MA. Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation. J Biol Chem 1993, 268(22):16265-16269.
25. Migita H, Morser J, Kawai K. Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells. FEBS Lett 2004, 561(1-3):69-74. 10.1016/S0014-5793(04)00118-8, 15013753.
26. Shukla A, Barrett TF, Nakayama KI, Nakayama K, Mossman BT, Lounsbury KM. Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. FASEB J 2006, 20(7):997-999. 10.1096/fj.05-4554fje, 16571779.
27. Tan RJ, Fattman CL, Niehouse LM, Tobolewski JM, Hanford LE, Li Q, Monzon FA, Parks WC, Oury TD. Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice. Am J Respir Cell Mol Biol 2006, 35(3):289-297. 10.1165/rcmb.2005-0471OC, 1820635,1820635, 16574944.
28. Opdenakker G, Van den Steen PE, Van Damme J. Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol 2001, 22(10):571-579. 10.1016/S1471-4906(01)02023-3, 11574282.
29. Gebhardt C, Nemeth J, Angel P, Hess J. S100A8 and S100A9 in inflammation and cancer. Biochem Pharmacol 2006, 72(11):1622-1631. 10.1016/j.bcp.2006.05.017, 16846592.
30. Beaver LM, Stemmy EJ, Schwartz AM, Damsker JM, Constant SL, Ceryak SM, Patierno SR. Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure. Environ Health Perspect 2009, 117(12):1896-1902. 2799464, 20049209.
31. Beaver LM, Stemmy EJ, Constant SL, Schwartz A, Little LG, Gigley JP, Chun G, Sugden KD, Ceryak SM, Patierno SR. Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. Toxicol Appl Pharmacol 2009, 235(1):47-56. 10.1016/j.taap.2008.11.018, 19109987.
32. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002, 420(6917):860-867. 10.1038/nature01322, 2803035, 12490959.
33. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 2001, 357(9255):539-545. 10.1016/S0140-6736(00)04046-0, 11229684.
34. Moody TW, Leyton J, Zakowicz H, Hida T, Kang Y, Jakowlew S, You L, Ozbun L, Zia H, Youngberg J, et al. Indomethacin reduces lung adenoma number in A/J mice. Anticancer Res 2001, 21(3B):1749-1755.