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Volumn 5, Issue 19, 2014, Pages 9065-9078

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma

Author keywords

2 DE; Gankyrin; Liposarcoma; Predictive factor; Tumorigenesis

Indexed keywords

GANKYRIN; MAMMALIAN TARGET OF RAPAMYCIN; ONCOPROTEIN; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MTOR PROTEIN, HUMAN; PROTEASOME; PROTEIN KINASE B; PSMD10 PROTEIN, HUMAN; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TUMOR MARKER;

EID: 84910052443     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2375     Document Type: Article
Times cited : (16)

References (46)
  • 1
    • 0028840074 scopus 로고
    • Sarcomas and other malignancies of soft tissue, retroperitoneum, peritoneum, pleura, heart, mediastinum, and spleen
    • Mack TM. Sarcomas and other malignancies of soft tissue, retroperitoneum, peritoneum, pleura, heart, mediastinum, and spleen. Cancer. 1995; 75(1 Suppl):211-244.
    • (1995) Cancer , vol.75 , Issue.1 , pp. 211-244
    • Mack, T.M.1
  • 5
    • 25444518461 scopus 로고    scopus 로고
    • MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data
    • Binh MB, Sastre-Garau X, Guillou L, de Pinieux G, Terrier P, Lagace R, Aurias A, Hostein I and Coindre JM. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol. 2005; 29(10):1340-1347.
    • (2005) Am J Surg Pathol , vol.29 , Issue.10 , pp. 1340-1347
    • Binh, M.B.1    Sastre-Garau, X.2    Guillou, L.3    de Pinieux, G.4    Terrier, P.5    Lagace, R.6    Aurias, A.7    Hostein, I.8    Coindre, J.M.9
  • 6
    • 34748907274 scopus 로고    scopus 로고
    • Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR
    • Sirvent N, Coindre JM, Maire G, Hostein I, Keslair F, Guillou L, Ranchere-Vince D, Terrier P and Pedeutour F. Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR. Am J Surg Pathol. 2007; 31(10):1476-1489.
    • (2007) Am J Surg Pathol , vol.31 , Issue.10 , pp. 1476-1489
    • Sirvent, N.1    Coindre, J.M.2    Maire, G.3    Hostein, I.4    Keslair, F.5    Guillou, L.6    Ranchere-Vince, D.7    Terrier, P.8    Pedeutour, F.9
  • 7
    • 73449118978 scopus 로고    scopus 로고
    • Can MDM2 and CDK4 make the diagnosis of well differentiated/dedifferentiated liposarcoma? An immunohistochemical study on 129 soft tissue tumours
    • Aleixo PB, Hartmann AA, Menezes IC, Meurer RT and Oliveira AM. Can MDM2 and CDK4 make the diagnosis of well differentiated/dedifferentiated liposarcoma? An immunohistochemical study on 129 soft tissue tumours. J Clin Pathol. 2009; 62(12):1127-1135.
    • (2009) J Clin Pathol , vol.62 , Issue.12 , pp. 1127-1135
    • Aleixo, P.B.1    Hartmann, A.A.2    Menezes, I.C.3    Meurer, R.T.4    Oliveira, A.M.5
  • 8
    • 33747637731 scopus 로고    scopus 로고
    • Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk
    • Dalal KM, Kattan MW, Antonescu CR, Brennan MF and Singer S. Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg. 2006; 244(3):381-391.
    • (2006) Ann Surg , vol.244 , Issue.3 , pp. 381-391
    • Dalal, K.M.1    Kattan, M.W.2    Antonescu, C.R.3    Brennan, M.F.4    Singer, S.5
  • 9
    • 54049085379 scopus 로고    scopus 로고
    • The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution
    • Mussi C, Collini P, Miceli R, Barisella M, Mariani L, Fiore M, Casali PG and Gronchi A. The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution. Cancer. 2008; 113(7):1657-1665.
    • (2008) Cancer , vol.113 , Issue.7 , pp. 1657-1665
    • Mussi, C.1    Collini, P.2    Miceli, R.3    Barisella, M.4    Mariani, L.5    Fiore, M.6    Casali, P.G.7    Gronchi, A.8
  • 10
    • 0141906807 scopus 로고    scopus 로고
    • Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma
    • discussion 370-351
    • Singer S, Antonescu CR, Riedel E and Brennan MF. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003; 238(3):358-370; discussion 370-351.
    • (2003) Ann Surg , vol.238 , Issue.3 , pp. 358-370
    • Singer, S.1    Antonescu, C.R.2    Riedel, E.3    Brennan, M.F.4
  • 11
    • 0037192842 scopus 로고    scopus 로고
    • Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome
    • Dawson S, Apcher S, Mee M, Higashitsuji H, Baker R, Uhle S, Dubiel W, Fujita J and Mayer RJ. Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome. J Biol Chem. 2002; 277(13):10893-10902.
    • (2002) J Biol Chem , vol.277 , Issue.13 , pp. 10893-10902
    • Dawson, S.1    Apcher, S.2    Mee, M.3    Higashitsuji, H.4    Baker, R.5    Uhle, S.6    Dubiel, W.7    Fujita, J.8    Mayer, R.J.9
  • 13
    • 46449102332 scopus 로고    scopus 로고
    • Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells
    • Qiu W, Wu J, Walsh EM, Zhang Y, Chen CY, Fujita J and Xiao ZX. Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells. Oncogene. 2008; 27(29):4034-4043.
    • (2008) Oncogene , vol.27 , Issue.29 , pp. 4034-4043
    • Qiu, W.1    Wu, J.2    Walsh, E.M.3    Zhang, Y.4    Chen, C.Y.5    Fujita, J.6    Xiao, Z.X.7
  • 17
    • 20444498521 scopus 로고    scopus 로고
    • Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma
    • Li H, Fu X, Chen Y, Hong Y, Tan Y, Cao H, Wu M and Wang H. Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology. 2005; 128(7):2029-2041.
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 2029-2041
    • Li, H.1    Fu, X.2    Chen, Y.3    Hong, Y.4    Tan, Y.5    Cao, H.6    Wu, M.7    Wang, H.8
  • 18
    • 70449528744 scopus 로고    scopus 로고
    • p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity
    • Dai RY, Chen Y, Fu J, Dong LW, Ren YB, Yang GZ, Qian YW, Cao J, Tang SH, Yang SL and Wang HY. p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity. Cell Res. 2009; 19(11):1243-1257.
    • (2009) Cell Res , vol.19 , Issue.11 , pp. 1243-1257
    • Dai, R.Y.1    Chen, Y.2    Fu, J.3    Dong, L.W.4    Ren, Y.B.5    Yang, G.Z.6    Qian, Y.W.7    Cao, J.8    Tang, S.H.9    Yang, S.L.10    Wang, H.Y.11
  • 19
    • 0036678085 scopus 로고    scopus 로고
    • Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance
    • Fu XY, Wang HY, Tan L, Liu SQ, Cao HF and Wu MC. Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance. World J Gastroenterol. 2002; 8(4):638-643.
    • (2002) World J Gastroenterol , vol.8 , Issue.4 , pp. 638-643
    • Fu, X.Y.1    Wang, H.Y.2    Tan, L.3    Liu, S.Q.4    Cao, H.F.5    Wu, M.C.6
  • 20
    • 39549122562 scopus 로고    scopus 로고
    • Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma
    • Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T and Fujita J. Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma. Hepatology. 2008; 47(2):493-502.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 493-502
    • Umemura, A.1    Itoh, Y.2    Itoh, K.3    Yamaguchi, K.4    Nakajima, T.5    Higashitsuji, H.6    Onoue, H.7    Fukumoto, M.8    Okanoue, T.9    Fujita, J.10
  • 21
    • 34547102253 scopus 로고    scopus 로고
    • Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma
    • Singer S, Socci ND, Ambrosini G, Sambol E, Decarolis P, Wu Y, O'Connor R, Maki R, Viale A, Sander C, Schwartz GK and Antonescu CR. Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer Res. 2007; 67(14):6626-6636.
    • (2007) Cancer Res , vol.67 , Issue.14 , pp. 6626-6636
    • Singer, S.1    Socci, N.D.2    Ambrosini, G.3    Sambol, E.4    Decarolis, P.5    Wu, Y.6    O'Connor, R.7    Maki, R.8    Viale, A.9    Sander, C.10    Schwartz, G.K.11    Antonescu, C.R.12
  • 24
    • 36849040707 scopus 로고    scopus 로고
    • Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance
    • Ortiz CM, Ito T, Tanaka E, Tsunoda S, Nagayama S, Sakai Y, Higashitsuji H, Fujita J and Shimada Y. Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance. Int J Cancer. 2008; 122(2):325-332.
    • (2008) Int J Cancer , vol.122 , Issue.2 , pp. 325-332
    • Ortiz, C.M.1    Ito, T.2    Tanaka, E.3    Tsunoda, S.4    Nagayama, S.5    Sakai, Y.6    Higashitsuji, H.7    Fujita, J.8    Shimada, Y.9
  • 25
    • 60849097292 scopus 로고    scopus 로고
    • Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells
    • Li X, Zhang Y, Xiong C, Jin H, Jing B, Zhang Y and Fan D. Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells. Cancer Invest. 2009; 27(2):129-139.
    • (2009) Cancer Invest , vol.27 , Issue.2 , pp. 129-139
    • Li, X.1    Zhang, Y.2    Xiong, C.3    Jin, H.4    Jing, B.5    Zhang, Y.6    Fan, D.7
  • 26
    • 0030250585 scopus 로고    scopus 로고
    • Liposarcoma: outcome and prognostic factors following conservation surgery and radiation therapy
    • Zagars GK, Goswitz MS and Pollack A. Liposarcoma: outcome and prognostic factors following conservation surgery and radiation therapy. Int J Radiat Oncol Biol Phys. 1996; 36(2):311-319.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , Issue.2 , pp. 311-319
    • Zagars, G.K.1    Goswitz, M.S.2    Pollack, A.3
  • 28
    • 0033993526 scopus 로고    scopus 로고
    • Influence of biologic factors and anatomic site in completely resected liposarcoma
    • Linehan DC, Lewis JJ, Leung D and Brennan MF. Influence of biologic factors and anatomic site in completely resected liposarcoma. J Clin Oncol. 2000; 18(8):1637-1643.
    • (2000) J Clin Oncol , vol.18 , Issue.8 , pp. 1637-1643
    • Linehan, D.C.1    Lewis, J.J.2    Leung, D.3    Brennan, M.F.4
  • 32
    • 79958857301 scopus 로고    scopus 로고
    • Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma
    • Crago AM and Singer S. Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma. Curr Opin Oncol. 2011; 23(4):373-378.
    • (2011) Curr Opin Oncol , vol.23 , Issue.4 , pp. 373-378
    • Crago, A.M.1    Singer, S.2
  • 33
    • 4644341568 scopus 로고    scopus 로고
    • The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma
    • discussion 695-687
    • Eilber FC, Eilber FR, Eckardt J, Rosen G, Riedel E, Maki RG, Brennan MF and Singer S. The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma. Ann Surg. 2004; 240(4):686-695; discussion 695-687.
    • (2004) Ann Surg , vol.240 , Issue.4 , pp. 686-695
    • Eilber, F.C.1    Eilber, F.R.2    Eckardt, J.3    Rosen, G.4    Riedel, E.5    Maki, R.G.6    Brennan, M.F.7    Singer, S.8
  • 34
    • 33745217875 scopus 로고    scopus 로고
    • Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas
    • Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, Bonichon F, Stoeckle E and Bui NB. Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas. Cancer. 2006; 106(12):2725-2733.
    • (2006) Cancer , vol.106 , Issue.12 , pp. 2725-2733
    • Fabre-Guillevin, E.1    Coindre, J.M.2    Somerhausen Nde, S.3    Bonichon, F.4    Stoeckle, E.5    Bui, N.B.6
  • 36
    • 70350633437 scopus 로고    scopus 로고
    • Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma
    • Horvai AE, DeVries S, Roy R, O'Donnell RJ and Waldman F. Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma. Mod Pathol. 2009; 22(11):1477-1488.
    • (2009) Mod Pathol , vol.22 , Issue.11 , pp. 1477-1488
    • Horvai, A.E.1    DeVries, S.2    Roy, R.3    O'Donnell, R.J.4    Waldman, F.5
  • 37
  • 38
    • 0035099918 scopus 로고    scopus 로고
    • Role of T antigen interactions with p53 in tumorigenesis
    • Pipas JM and Levine AJ. Role of T antigen interactions with p53 in tumorigenesis. Semin Cancer Biol. 2001; 11(1):23-30.
    • (2001) Semin Cancer Biol , vol.11 , Issue.1 , pp. 23-30
    • Pipas, J.M.1    Levine, A.J.2
  • 39
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein B, Lane D and Levine AJ. Surfing the p53 network. Nature. 2000; 408(6810):307-310.
    • (2000) Nature , vol.408 , Issue.6810 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 42
    • 0033380090 scopus 로고    scopus 로고
    • Signalling networks that cause cancer
    • McCormick F. Signalling networks that cause cancer. Trends Cell Biol. 1999; 9(12):M53-56.
    • (1999) Trends Cell Biol , vol.9 , Issue.12 , pp. M53-56
    • McCormick, F.1
  • 43
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: rationale and promise
    • Luo J, Manning BD and Cantley LC. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell. 2003; 4(4):257-262.
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.