Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: Utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR

American Journal of Surgical Pathology

Volumn 31, Issue 10, 2007, Pages 1476-1489

  Sirvent, Nicolas ^a,b   Coindre, Jean Michel ^c   Maire, Georges ^a,g   Hostein, Isabelle ^c   Keslair, Frédérique ^a   Guillou, Louis ^f   Ranchere Vince, Dominique ^d   Terrier, Philippe ^e   Pedeutour, Florence ^a,h  

^a CENTRE DE BIOCHIMIE   (France)

^b UNIVERSITY HOSPITAL OF NICE   (France)

^c INSTITUT BERGONIÉ   (France)

^d CENTRE LÉON BÉRARD   (France)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f UNIVERSITY INSTITUTE OF PATHOLOGY   (Switzerland)

^g PRINCESS MARGARET HOSPITAL   (Canada)

^h UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

CDK4; Fluorescence in situ hybridization; Genomic amplification; Immunohistochemistry; Lipoma; Liposarcoma; MDM2

Indexed keywords

CYCLIN DEPENDENT KINASE 4; PARAFFIN; PROTEIN MDM2;

ADIPOCYTE; ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; ARTICLE; BENIGN TUMOR; CELL DAMAGE; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFORMATION; LIPOMA; LIPOSARCOMA; MALE; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SAMPLE; SOFT TISSUE TUMOR; TUMOR CELL;

ADIPOCYTES; ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; CYCLIN-DEPENDENT KINASE 4; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LIPOMA; LIPOSARCOMA; MALE; MIDDLE AGED; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PARAFFIN EMBEDDING; PROTO-ONCOGENE PROTEINS C-MDM2; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOFT TISSUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 34748907274     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/PAS.0b013e3180581fff     Document Type: Article

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