메뉴 건너뛰기




Volumn 99, Issue 11, 2014, Pages E2308-E2316

Both low and high serum IGF-1 levels associate with increased risk of cardiovascular events in elderly men

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; SOMATOMEDIN C;

EID: 84910020575     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-1575     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 68549092476 scopus 로고    scopus 로고
    • The role of liver-derived insulin-like growth factor-I
    • Ohlsson C, Mohan S, Sjögren K, et al. The role of liver-derived insulin-like growth factor-I. Endocr Rev. 2009; 30: 494-535.
    • (2009) Endocr Rev , vol.30 , pp. 494-535
    • Ohlsson, C.1    Mohan, S.2    Sjögren, K.3
  • 2
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: Overview and recent insights. Endocr Rev. 2007; 28: 20-47.
    • (2007) Endocr Rev , vol.28 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    Leroith, D.3    Brodt, P.4
  • 3
    • 0034682622 scopus 로고    scopus 로고
    • Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial
    • Sesmilo G, Biller BM, Llevadot J, et al. Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial. Ann Intern Med. 2000; 133: 111-122.
    • (2000) Ann Intern Med , vol.133 , pp. 111-122
    • Sesmilo, G.1    Biller, B.M.2    Llevadot, J.3
  • 4
    • 56149096729 scopus 로고    scopus 로고
    • Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects
    • Succurro E, Andreozzi F, Sciacqua A, et al. Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects. Diabetes Care. 2008; 31: 1886-1888.
    • (2008) Diabetes Care , vol.31 , pp. 1886-1888
    • Succurro, E.1    Andreozzi, F.2    Sciacqua, A.3
  • 6
    • 13044294029 scopus 로고    scopus 로고
    • Liver-derived insulin-like growth factor i (IGF-1) is the principal source of IGF-1 in blood but is not required for postnatal body growth in mice
    • Sjögren K, Liu JL, Blad K, et al. Liver-derived insulin-like growth factor I (IGF-1) is the principal source of IGF-1 in blood but is not required for postnatal body growth in mice. Proc Natl Acad Sci U S A. 1999; 96: 7088-7092.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7088-7092
    • Sjögren, K.1    Liu, J.L.2    Blad, K.3
  • 7
    • 0033594893 scopus 로고    scopus 로고
    • Normal growth and development in the absence of hepatic insulin-like growth factor i
    • Yakar S, Liu JL, Stannard B, et al. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci U S A. 1999; 96: 7324-7329.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7324-7329
    • Yakar, S.1    Liu, J.L.2    Stannard, B.3
  • 8
    • 0037143639 scopus 로고    scopus 로고
    • Low serum insulin-like growth factor i is associated with increased risk of ischemic heart disease: A population-based case-control study
    • Juul A, Scheike T, Davidsen M, Gyllenborg J, Jorgensen T. Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study. Circulation. 2002; 106: 939-944.
    • (2002) Circulation , vol.106 , pp. 939-944
    • Juul, A.1    Scheike, T.2    Davidsen, M.3    Gyllenborg, J.4    Jorgensen, T.5
  • 9
    • 80053247458 scopus 로고    scopus 로고
    • Effects of insulin-like growth factor 1 in preventing acute coronary syndromes: The PRIME study
    • Ruidavets JB, Luc G, Machez E, et al. Effects of insulin-like growth factor 1 in preventing acute coronary syndromes: The PRIME study. Atherosclerosis. 2011; 218: 464-469.
    • (2011) Atherosclerosis , vol.218 , pp. 464-469
    • Ruidavets, J.B.1    Luc, G.2    Machez, E.3
  • 10
    • 0035126968 scopus 로고    scopus 로고
    • Apolymorphism in the gene for IGF-1: Functional properties and risk for type 2 diabetes and myocardial infarction
    • Vaessen N, Heutink P, Janssen JA, et al.Apolymorphism in the gene for IGF-1: Functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes. 2001; 50: 637-642.
    • (2001) Diabetes , vol.50 , pp. 637-642
    • Vaessen, N.1    Heutink, P.2    Janssen, J.A.3
  • 11
    • 34147183436 scopus 로고    scopus 로고
    • Association of total insulin-like growth factor-I, insulin-like growth factor binding protein- 1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke
    • Kaplan RC, McGinn AP, Pollak MN, et al. Association of total insulin-like growth factor-I, insulin-like growth factor binding protein- 1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke. J Clin Endocrinol Metab. 2007; 92: 1319-1325.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1319-1325
    • Kaplan, R.C.1    McGinn, A.P.2    Pollak, M.N.3
  • 12
    • 27744592942 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke
    • Johnsen SP, Hundborg HH, Sorensen HT, et al. Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke. J Clin Endocrinol Metab. 2005; 90: 5937-5941.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5937-5941
    • Johnsen, S.P.1    Hundborg, H.H.2    Sorensen, H.T.3
  • 13
    • 0842291511 scopus 로고    scopus 로고
    • The prospective association of serum insulin-like growth factor i (IGF-1) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: The Rancho Bernardo Study
    • Laughlin GA, Barrett-Connor E, Criqui MH, Kritz-Silverstein D. The prospective association of serum insulin-like growth factor I (IGF-1) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: The Rancho Bernardo Study. J Clin Endocrinol Metab. 2004; 89: 114-120.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 114-120
    • Laughlin, G.A.1    Barrett-Connor, E.2    Criqui, M.H.3    Kritz-Silverstein, D.4
  • 14
    • 84870728818 scopus 로고    scopus 로고
    • Both low and high serum IGF-1 levels associate with cancer mortality in older men
    • Svensson J, Carlzon D, Petzold M, et al. 2012 Both Low and High Serum IGF-1 Levels Associate with Cancer Mortality in Older Men. J Clin Endocrinol Metab.
    • (2012) J Clin Endocrinol Metab
    • Svensson, J.1    Carlzon, D.2    Petzold, M.3
  • 15
    • 77957801613 scopus 로고    scopus 로고
    • The association of serum insulin-like growth factor-I with mortality, cardiovascular disease, and cancer in the elderly: A population-based study
    • van Bunderen CC, van Nieuwpoort IC, van Schoor NM, Deeg DJ, Lips P, Drent ML. The association of serum insulin-like growth factor-I with mortality, cardiovascular disease, and cancer in the elderly: A population-based study. J Clin Endocrinol Metab. 2010; 95: 4616-4624.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4616-4624
    • Van Bunderen, C.C.1    Van Nieuwpoort, I.C.2    Van Schoor, N.M.3    Deeg, D.J.4    Lips, P.5    Drent, M.L.6
  • 16
    • 66149101010 scopus 로고    scopus 로고
    • Mortality and serum insulinlike growth factor (IGF)-I and IGF binding protein 3 concentrations
    • Friedrich N, Haring R, Nauck M, et al. Mortality and serum insulinlike growth factor (IGF)-I and IGF binding protein 3 concentrations. J Clin Endocrinol Metab. 2009; 94: 1732-1739.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1732-1739
    • Friedrich, N.1    Haring, R.2    Nauck, M.3
  • 18
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • Rosén T, Bengtsson BA. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 1990; 336: 285-288.
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosén, T.1    Bengtsson, B.A.2
  • 19
    • 3242712491 scopus 로고    scopus 로고
    • Malignant disease and cardiovascular morbidity in hypopituitary adults with or without growth hormone replacement therapy
    • Svensson J, Bengtsson BA, Rosén T, Oden A, Johannsson G. Malignant disease and cardiovascular morbidity in hypopituitary adults with or without growth hormone replacement therapy. J Clin Endocrinol Metab. 2004; 89: 3306-3312.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3306-3312
    • Svensson, J.1    Bengtsson, B.A.2    Rosén, T.3    Oden, A.4    Johannsson, G.5
  • 20
    • 0035835469 scopus 로고    scopus 로고
    • Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group
    • Tomlinson JW, Holden N, Hills RK, et al. Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet. 2001; 357: 425-431.
    • (2001) Lancet , vol.357 , pp. 425-431
    • Tomlinson, J.W.1    Holden, N.2    Hills, R.K.3
  • 22
    • 0022036752 scopus 로고
    • Sexual dimorphism in the control of growth hormone secretion
    • Jansson JO, Edén S, Isaksson O. Sexual dimorphism in the control of growth hormone secretion. Endocr Rev. 1985; 6: 128-150.
    • (1985) Endocr Rev , vol.6 , pp. 128-150
    • Jansson, J.O.1    Edén, S.2    Isaksson, O.3
  • 23
    • 33645333405 scopus 로고    scopus 로고
    • Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden
    • Mellström D, Johnell O, Ljunggren O, et al. Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res. 2006; 21: 529-535.
    • (2006) J Bone Miner Res , vol.21 , pp. 529-535
    • Mellström, D.1    Johnell, O.2    Ljunggren, O.3
  • 24
    • 24144490059 scopus 로고    scopus 로고
    • Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study - A large observational study of the determinants of fracture in older men
    • Orwoll E, Blank JB, Barrett-Connor E, et al. Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study-a large observational study of the determinants of fracture in older men. Contemp Clin Trials. 2005; 26: 569-585.
    • (2005) Contemp Clin Trials , vol.26 , pp. 569-585
    • Orwoll, E.1    Blank, J.B.2    Barrett-Connor, E.3
  • 25
    • 0034037078 scopus 로고    scopus 로고
    • Comparison of different procedures to identify probable cases of myocardial infarction and stroke in two Swedish prospective cohort studies using local and national routine registers
    • Merlo J, Lindblad U, Pessah-Rasmussen H, et al. Comparison of different procedures to identify probable cases of myocardial infarction and stroke in two Swedish prospective cohort studies using local and national routine registers. Eur J Epidemiol. 2000; 16: 235-243.
    • (2000) Eur J Epidemiol , vol.16 , pp. 235-243
    • Merlo, J.1    Lindblad, U.2    Pessah-Rasmussen, H.3
  • 26
    • 0024596532 scopus 로고
    • Flexible regression models with cubic splines
    • Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med. 1989; 8: 551-561.
    • (1989) Stat Med , vol.8 , pp. 551-561
    • Durrleman, S.1    Simon, R.2
  • 28
    • 0031862937 scopus 로고    scopus 로고
    • Serum total IGF-1, free IGF-1, and IGFB-1 levels in an elderly population: Relation to cardiovascular risk factors and disease
    • Janssen JA, Stolk RP, Pols HA, Grobbee DE, Lamberts SW. Serum total IGF-1, free IGF-1, and IGFB-1 levels in an elderly population: Relation to cardiovascular risk factors and disease. Arterioscler Thromb Vasc Biol. 1998; 18: 277-282.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 277-282
    • Janssen, J.A.1    Stolk, R.P.2    Pols, H.A.3    Grobbee, D.E.4    Lamberts, S.W.5
  • 29
    • 47549088668 scopus 로고    scopus 로고
    • Low circulating insulin-like growth factor i bioactivity in elderly men is associated with increased mortality
    • Brugts MP, van den Beld AW, Hofland LJ, et al. Low circulating insulin-like growth factor I bioactivity in elderly men is associated with increased mortality. J Clin Endocrinol Metab. 2008; 93: 2515-2522.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2515-2522
    • Brugts, M.P.1    Van Den Beld, A.W.2    Hofland, L.J.3
  • 30
    • 80052548094 scopus 로고    scopus 로고
    • Meta-analysis and dose-response metaregression: Circulating insulin-like growth factor i (IGF-1) and mortality
    • Burgers AM, Biermasz NR, Schoones JW, et al. Meta-analysis and dose-response metaregression: Circulating insulin-like growth factor I (IGF-1) and mortality. J Clin Endocrinol Metab. 2011; 96: 2912-2920.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2912-2920
    • Burgers, A.M.1    Biermasz, N.R.2    Schoones, J.W.3
  • 31
    • 0142056143 scopus 로고    scopus 로고
    • Serum insulin-like growth factor i and risk for heart failure in elderly individuals without a previous myocardial infarction: The Framingham Heart Study
    • Vasan RS, Sullivan LM, D'Agostino RB, et al. Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: The Framingham Heart Study. Ann Intern Med. 2003; 139: 642-648.
    • (2003) Ann Intern Med , vol.139 , pp. 642-648
    • Vasan, R.S.1    Sullivan, L.M.2    D'agostino, R.B.3
  • 32
    • 79955530877 scopus 로고    scopus 로고
    • Associations of IGF1 and IGFBPs 1 and 3 with all-cause and cardiovascular mortality in older men: The Health in Men Study
    • Yeap BB, Chubb SA, McCaul KA, et al. Associations of IGF1 and IGFBPs 1 and 3 with all-cause and cardiovascular mortality in older men: The Health In Men Study. Eur J Endocrinol. 2011; 164: 715-723.
    • (2011) Eur J Endocrinol , vol.164 , pp. 715-723
    • Yeap, B.B.1    Chubb, S.A.2    McCaul, K.A.3
  • 33
    • 0030454148 scopus 로고    scopus 로고
    • Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind placebo-controlled study
    • BögerRH, Skamira C, Bode- BögerSM, Brabant G, von zur Muhlen A, Frolich JC. Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study. J Clin Invest. 1996; 98: 2706-2713.
    • (1996) J Clin Invest , vol.98 , pp. 2706-2713
    • Böger, R.H.1    Skamira, C.2    Bode-Böger, S.M.3    Brabant, G.4    Von Zur Muhlen, A.5    Frolich, J.C.6
  • 34
    • 77954845856 scopus 로고    scopus 로고
    • Mortality in patients with pituitary disease
    • Sherlock M, Ayuk J, Tomlinson JW, et al. Mortality in patients with pituitary disease. Endocr Rev. 2010; 31: 301-342.
    • (2010) Endocr Rev , vol.31 , pp. 301-342
    • Sherlock, M.1    Ayuk, J.2    Tomlinson, J.W.3
  • 35
    • 0038646354 scopus 로고    scopus 로고
    • Cardiovascular function in acromegaly
    • Clayton RN. Cardiovascular function in acromegaly. Endocr Rev. 2003; 24: 272-277.
    • (2003) Endocr Rev , vol.24 , pp. 272-277
    • Clayton, R.N.1
  • 36
    • 1442326975 scopus 로고    scopus 로고
    • Systemic complications of acromegaly: Epidemiology, pathogenesis, and management
    • Colao A, Ferone D, Marzullo P, Lombardi G. Systemic complications of acromegaly: Epidemiology, pathogenesis, and management. Endocr Rev. 2004; 25: 102-152.
    • (2004) Endocr Rev , vol.25 , pp. 102-152
    • Colao, A.1    Ferone, D.2    Marzullo, P.3    Lombardi, G.4
  • 37
    • 79955647950 scopus 로고    scopus 로고
    • Changes in arterial stiffness but not carotid intimal thickness in acromegaly
    • Paisley AN, Banerjee M, Rezai M, et al. Changes in arterial stiffness but not carotid intimal thickness in acromegaly. J Clin Endocrinol Metab. 2011; 96: 1486-1492.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1486-1492
    • Paisley, A.N.1    Banerjee, M.2    Rezai, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.