-
1
-
-
68549092476
-
The role of liver-derived insulin-like growth factor-I
-
Ohlsson C, Mohan S, Sjögren K, et al. The role of liver-derived insulin-like growth factor-I. Endocr Rev. 2009; 30: 494-535.
-
(2009)
Endocr Rev
, vol.30
, pp. 494-535
-
-
Ohlsson, C.1
Mohan, S.2
Sjögren, K.3
-
2
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: Overview and recent insights. Endocr Rev. 2007; 28: 20-47.
-
(2007)
Endocr Rev
, vol.28
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
Leroith, D.3
Brodt, P.4
-
3
-
-
0034682622
-
Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial
-
Sesmilo G, Biller BM, Llevadot J, et al. Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial. Ann Intern Med. 2000; 133: 111-122.
-
(2000)
Ann Intern Med
, vol.133
, pp. 111-122
-
-
Sesmilo, G.1
Biller, B.M.2
Llevadot, J.3
-
4
-
-
56149096729
-
Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects
-
Succurro E, Andreozzi F, Sciacqua A, et al. Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects. Diabetes Care. 2008; 31: 1886-1888.
-
(2008)
Diabetes Care
, vol.31
, pp. 1886-1888
-
-
Succurro, E.1
Andreozzi, F.2
Sciacqua, A.3
-
6
-
-
13044294029
-
Liver-derived insulin-like growth factor i (IGF-1) is the principal source of IGF-1 in blood but is not required for postnatal body growth in mice
-
Sjögren K, Liu JL, Blad K, et al. Liver-derived insulin-like growth factor I (IGF-1) is the principal source of IGF-1 in blood but is not required for postnatal body growth in mice. Proc Natl Acad Sci U S A. 1999; 96: 7088-7092.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7088-7092
-
-
Sjögren, K.1
Liu, J.L.2
Blad, K.3
-
7
-
-
0033594893
-
Normal growth and development in the absence of hepatic insulin-like growth factor i
-
Yakar S, Liu JL, Stannard B, et al. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci U S A. 1999; 96: 7324-7329.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7324-7329
-
-
Yakar, S.1
Liu, J.L.2
Stannard, B.3
-
8
-
-
0037143639
-
Low serum insulin-like growth factor i is associated with increased risk of ischemic heart disease: A population-based case-control study
-
Juul A, Scheike T, Davidsen M, Gyllenborg J, Jorgensen T. Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study. Circulation. 2002; 106: 939-944.
-
(2002)
Circulation
, vol.106
, pp. 939-944
-
-
Juul, A.1
Scheike, T.2
Davidsen, M.3
Gyllenborg, J.4
Jorgensen, T.5
-
9
-
-
80053247458
-
Effects of insulin-like growth factor 1 in preventing acute coronary syndromes: The PRIME study
-
Ruidavets JB, Luc G, Machez E, et al. Effects of insulin-like growth factor 1 in preventing acute coronary syndromes: The PRIME study. Atherosclerosis. 2011; 218: 464-469.
-
(2011)
Atherosclerosis
, vol.218
, pp. 464-469
-
-
Ruidavets, J.B.1
Luc, G.2
Machez, E.3
-
10
-
-
0035126968
-
Apolymorphism in the gene for IGF-1: Functional properties and risk for type 2 diabetes and myocardial infarction
-
Vaessen N, Heutink P, Janssen JA, et al.Apolymorphism in the gene for IGF-1: Functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes. 2001; 50: 637-642.
-
(2001)
Diabetes
, vol.50
, pp. 637-642
-
-
Vaessen, N.1
Heutink, P.2
Janssen, J.A.3
-
11
-
-
34147183436
-
Association of total insulin-like growth factor-I, insulin-like growth factor binding protein- 1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke
-
Kaplan RC, McGinn AP, Pollak MN, et al. Association of total insulin-like growth factor-I, insulin-like growth factor binding protein- 1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke. J Clin Endocrinol Metab. 2007; 92: 1319-1325.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1319-1325
-
-
Kaplan, R.C.1
McGinn, A.P.2
Pollak, M.N.3
-
12
-
-
27744592942
-
Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke
-
Johnsen SP, Hundborg HH, Sorensen HT, et al. Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke. J Clin Endocrinol Metab. 2005; 90: 5937-5941.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5937-5941
-
-
Johnsen, S.P.1
Hundborg, H.H.2
Sorensen, H.T.3
-
13
-
-
0842291511
-
The prospective association of serum insulin-like growth factor i (IGF-1) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: The Rancho Bernardo Study
-
Laughlin GA, Barrett-Connor E, Criqui MH, Kritz-Silverstein D. The prospective association of serum insulin-like growth factor I (IGF-1) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: The Rancho Bernardo Study. J Clin Endocrinol Metab. 2004; 89: 114-120.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 114-120
-
-
Laughlin, G.A.1
Barrett-Connor, E.2
Criqui, M.H.3
Kritz-Silverstein, D.4
-
14
-
-
84870728818
-
Both low and high serum IGF-1 levels associate with cancer mortality in older men
-
Svensson J, Carlzon D, Petzold M, et al. 2012 Both Low and High Serum IGF-1 Levels Associate with Cancer Mortality in Older Men. J Clin Endocrinol Metab.
-
(2012)
J Clin Endocrinol Metab
-
-
Svensson, J.1
Carlzon, D.2
Petzold, M.3
-
15
-
-
77957801613
-
The association of serum insulin-like growth factor-I with mortality, cardiovascular disease, and cancer in the elderly: A population-based study
-
van Bunderen CC, van Nieuwpoort IC, van Schoor NM, Deeg DJ, Lips P, Drent ML. The association of serum insulin-like growth factor-I with mortality, cardiovascular disease, and cancer in the elderly: A population-based study. J Clin Endocrinol Metab. 2010; 95: 4616-4624.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 4616-4624
-
-
Van Bunderen, C.C.1
Van Nieuwpoort, I.C.2
Van Schoor, N.M.3
Deeg, D.J.4
Lips, P.5
Drent, M.L.6
-
16
-
-
66149101010
-
Mortality and serum insulinlike growth factor (IGF)-I and IGF binding protein 3 concentrations
-
Friedrich N, Haring R, Nauck M, et al. Mortality and serum insulinlike growth factor (IGF)-I and IGF binding protein 3 concentrations. J Clin Endocrinol Metab. 2009; 94: 1732-1739.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1732-1739
-
-
Friedrich, N.1
Haring, R.2
Nauck, M.3
-
17
-
-
84874034962
-
Serum IGF1 metabolic syndrome, and incident cardiovascular disease in older people: A population-based study
-
van BunderenCC, OosterwerffMM, van Schoor NM, Deeg DJ, Lips P, Drent ML. Serum IGF1, metabolic syndrome, and incident cardiovascular disease in older people: A population-based study. Eur J Endocrinol. 2013; 168: 393-401.
-
(2013)
Eur J Endocrinol
, vol.168
, pp. 393-401
-
-
Van Bunderen, C.C.1
Oosterwerff, M.M.2
Van Schoor, N.M.3
Deeg, D.J.4
Lips, P.5
Drent, M.L.6
-
18
-
-
0025333249
-
Premature mortality due to cardiovascular disease in hypopituitarism
-
Rosén T, Bengtsson BA. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 1990; 336: 285-288.
-
(1990)
Lancet
, vol.336
, pp. 285-288
-
-
Rosén, T.1
Bengtsson, B.A.2
-
19
-
-
3242712491
-
Malignant disease and cardiovascular morbidity in hypopituitary adults with or without growth hormone replacement therapy
-
Svensson J, Bengtsson BA, Rosén T, Oden A, Johannsson G. Malignant disease and cardiovascular morbidity in hypopituitary adults with or without growth hormone replacement therapy. J Clin Endocrinol Metab. 2004; 89: 3306-3312.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3306-3312
-
-
Svensson, J.1
Bengtsson, B.A.2
Rosén, T.3
Oden, A.4
Johannsson, G.5
-
20
-
-
0035835469
-
Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group
-
Tomlinson JW, Holden N, Hills RK, et al. Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet. 2001; 357: 425-431.
-
(2001)
Lancet
, vol.357
, pp. 425-431
-
-
Tomlinson, J.W.1
Holden, N.2
Hills, R.K.3
-
21
-
-
58249090529
-
IGF1 as predictor of all cause mortality and cardiovascular disease in an elderly population
-
Andreassen M, Raymond I, Kistorp C, Hildebrandt P, Faber J, Kristensen LØ. IGF1 as predictor of all cause mortality and cardiovascular disease in an elderly population. Eur J Endocrinol. 2009; 160: 25-31.
-
(2009)
Eur J Endocrinol
, vol.160
, pp. 25-31
-
-
Andreassen, M.1
Raymond, I.2
Kistorp, C.3
Hildebrandt, P.4
Faber, J.5
Kristensen, L.O.6
-
22
-
-
0022036752
-
Sexual dimorphism in the control of growth hormone secretion
-
Jansson JO, Edén S, Isaksson O. Sexual dimorphism in the control of growth hormone secretion. Endocr Rev. 1985; 6: 128-150.
-
(1985)
Endocr Rev
, vol.6
, pp. 128-150
-
-
Jansson, J.O.1
Edén, S.2
Isaksson, O.3
-
23
-
-
33645333405
-
Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden
-
Mellström D, Johnell O, Ljunggren O, et al. Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res. 2006; 21: 529-535.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 529-535
-
-
Mellström, D.1
Johnell, O.2
Ljunggren, O.3
-
24
-
-
24144490059
-
Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study - A large observational study of the determinants of fracture in older men
-
Orwoll E, Blank JB, Barrett-Connor E, et al. Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study-a large observational study of the determinants of fracture in older men. Contemp Clin Trials. 2005; 26: 569-585.
-
(2005)
Contemp Clin Trials
, vol.26
, pp. 569-585
-
-
Orwoll, E.1
Blank, J.B.2
Barrett-Connor, E.3
-
25
-
-
0034037078
-
Comparison of different procedures to identify probable cases of myocardial infarction and stroke in two Swedish prospective cohort studies using local and national routine registers
-
Merlo J, Lindblad U, Pessah-Rasmussen H, et al. Comparison of different procedures to identify probable cases of myocardial infarction and stroke in two Swedish prospective cohort studies using local and national routine registers. Eur J Epidemiol. 2000; 16: 235-243.
-
(2000)
Eur J Epidemiol
, vol.16
, pp. 235-243
-
-
Merlo, J.1
Lindblad, U.2
Pessah-Rasmussen, H.3
-
26
-
-
0024596532
-
Flexible regression models with cubic splines
-
Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med. 1989; 8: 551-561.
-
(1989)
Stat Med
, vol.8
, pp. 551-561
-
-
Durrleman, S.1
Simon, R.2
-
28
-
-
0031862937
-
Serum total IGF-1, free IGF-1, and IGFB-1 levels in an elderly population: Relation to cardiovascular risk factors and disease
-
Janssen JA, Stolk RP, Pols HA, Grobbee DE, Lamberts SW. Serum total IGF-1, free IGF-1, and IGFB-1 levels in an elderly population: Relation to cardiovascular risk factors and disease. Arterioscler Thromb Vasc Biol. 1998; 18: 277-282.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 277-282
-
-
Janssen, J.A.1
Stolk, R.P.2
Pols, H.A.3
Grobbee, D.E.4
Lamberts, S.W.5
-
29
-
-
47549088668
-
Low circulating insulin-like growth factor i bioactivity in elderly men is associated with increased mortality
-
Brugts MP, van den Beld AW, Hofland LJ, et al. Low circulating insulin-like growth factor I bioactivity in elderly men is associated with increased mortality. J Clin Endocrinol Metab. 2008; 93: 2515-2522.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 2515-2522
-
-
Brugts, M.P.1
Van Den Beld, A.W.2
Hofland, L.J.3
-
30
-
-
80052548094
-
Meta-analysis and dose-response metaregression: Circulating insulin-like growth factor i (IGF-1) and mortality
-
Burgers AM, Biermasz NR, Schoones JW, et al. Meta-analysis and dose-response metaregression: Circulating insulin-like growth factor I (IGF-1) and mortality. J Clin Endocrinol Metab. 2011; 96: 2912-2920.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 2912-2920
-
-
Burgers, A.M.1
Biermasz, N.R.2
Schoones, J.W.3
-
31
-
-
0142056143
-
Serum insulin-like growth factor i and risk for heart failure in elderly individuals without a previous myocardial infarction: The Framingham Heart Study
-
Vasan RS, Sullivan LM, D'Agostino RB, et al. Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: The Framingham Heart Study. Ann Intern Med. 2003; 139: 642-648.
-
(2003)
Ann Intern Med
, vol.139
, pp. 642-648
-
-
Vasan, R.S.1
Sullivan, L.M.2
D'agostino, R.B.3
-
32
-
-
79955530877
-
Associations of IGF1 and IGFBPs 1 and 3 with all-cause and cardiovascular mortality in older men: The Health in Men Study
-
Yeap BB, Chubb SA, McCaul KA, et al. Associations of IGF1 and IGFBPs 1 and 3 with all-cause and cardiovascular mortality in older men: The Health In Men Study. Eur J Endocrinol. 2011; 164: 715-723.
-
(2011)
Eur J Endocrinol
, vol.164
, pp. 715-723
-
-
Yeap, B.B.1
Chubb, S.A.2
McCaul, K.A.3
-
33
-
-
0030454148
-
Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind placebo-controlled study
-
BögerRH, Skamira C, Bode- BögerSM, Brabant G, von zur Muhlen A, Frolich JC. Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study. J Clin Invest. 1996; 98: 2706-2713.
-
(1996)
J Clin Invest
, vol.98
, pp. 2706-2713
-
-
Böger, R.H.1
Skamira, C.2
Bode-Böger, S.M.3
Brabant, G.4
Von Zur Muhlen, A.5
Frolich, J.C.6
-
34
-
-
77954845856
-
Mortality in patients with pituitary disease
-
Sherlock M, Ayuk J, Tomlinson JW, et al. Mortality in patients with pituitary disease. Endocr Rev. 2010; 31: 301-342.
-
(2010)
Endocr Rev
, vol.31
, pp. 301-342
-
-
Sherlock, M.1
Ayuk, J.2
Tomlinson, J.W.3
-
35
-
-
0038646354
-
Cardiovascular function in acromegaly
-
Clayton RN. Cardiovascular function in acromegaly. Endocr Rev. 2003; 24: 272-277.
-
(2003)
Endocr Rev
, vol.24
, pp. 272-277
-
-
Clayton, R.N.1
-
36
-
-
1442326975
-
Systemic complications of acromegaly: Epidemiology, pathogenesis, and management
-
Colao A, Ferone D, Marzullo P, Lombardi G. Systemic complications of acromegaly: Epidemiology, pathogenesis, and management. Endocr Rev. 2004; 25: 102-152.
-
(2004)
Endocr Rev
, vol.25
, pp. 102-152
-
-
Colao, A.1
Ferone, D.2
Marzullo, P.3
Lombardi, G.4
-
37
-
-
79955647950
-
Changes in arterial stiffness but not carotid intimal thickness in acromegaly
-
Paisley AN, Banerjee M, Rezai M, et al. Changes in arterial stiffness but not carotid intimal thickness in acromegaly. J Clin Endocrinol Metab. 2011; 96: 1486-1492.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 1486-1492
-
-
Paisley, A.N.1
Banerjee, M.2
Rezai, M.3
|