The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway

Biochemical and Biophysical Research Communications

Volumn 454, Issue 3, 2014, Pages 364-368

  Takamiya, Rina ^a   Takahashi, Motoko ^a   Uehara, Yasuaki ^a   Ariki, Shigeru ^a   Hashimoto, Jiro ^a   Hasegawa, Yoshihiro ^a   Kuroki, Yoshio ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ErbB; Heregulin 1; HIF 1; Nrf2

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 3; GLYCAN; HEREGULIN BETA1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ERBB3 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER CELL LINE; CARCINOGENESIS; CELL MIGRATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DELETION MUTANT; HUMAN; HUMAN CELL; MCF 7 CELL LINE; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR GROWTH; WILD TYPE; BREAST; BREAST TUMOR; CELL MOTION; CHEMISTRY; DISEASE COURSE; FEMALE; GENE DELETION; GENETICS; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; POINT MUTATION; SOLUBILITY; TUMOR CELL LINE;

BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE PROGRESSION; FEMALE; GENE DELETION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MCF-7 CELLS; NEUREGULIN-1; NF-E2-RELATED FACTOR 2; POINT MUTATION; RECEPTOR, ERBB-3; SIGNAL TRANSDUCTION; SOLUBILITY;

EID: 84910010876     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.086     Document Type: Article

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