High level of reactive oxygen species impaired mesenchymal stem cell migration via overpolymerization of F-actin cytoskeleton in systemic lupus erythematosus

Pathologie Biologie

Volumn 62, Issue 6, 2014, Pages 382-390

  Shi, D ^a   Li, X ^a   Chen, H ^a   Che, N ^b   Zhou, S ^a   Lu, Z ^b   Shi, S ^c   Sun, L ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

F actin; Mesenchymal stem cells; Migration; MRL lpr mice; NAC; Reactive oxygen species; Systemic lupus erythematosus

Indexed keywords

ACETYLCYSTEINE; AUTOANTIBODY; F ACTIN; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; ACTIN;

ACTIN FILAMENT; ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CELL CULTURE; CELL LEVEL; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; POLYMERIZATION; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL MOTION; DRUG EFFECTS; MESENCHYMAL STROMA CELL; METABOLISM; MIDDLE AGED; MUTANT MOUSE STRAIN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN MULTIMERIZATION; YOUNG ADULT;

ACTIN CYTOSKELETON; ACTINS; ADOLESCENT; ADULT; ANIMALS; CASE-CONTROL STUDIES; CELL MOVEMENT; CELLS, CULTURED; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MIDDLE AGED; PROTEIN MULTIMERIZATION; REACTIVE OXYGEN SPECIES; YOUNG ADULT;

EID: 84910006143     PISSN: 03698114     EISSN: 17683114     Source Type: Journal    
DOI: 10.1016/j.patbio.2014.07.009     Document Type: Article

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