Monocyte-derived dendritic cells from patients with dermatophytosis restrict the growth of Trichophyton rubrum and induce CD4-T cell activation

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Santiago, Karla ^a   Bomfim, Gisele Facholi ^a,b   Criado, Paulo Ricardo ^a   Almeida, Sandro Rogerio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; MANNOSE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADULT; AGED; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL INTERACTION; CELL VIABILITY; CLINICAL ARTICLE; CONIDIUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DERMATOPHYTE; DERMATOPHYTOSIS; EXPOSURE; FEMALE; FUNGUS GROWTH; GROWTH INHIBITION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; PHAGOCYTOSIS; T LYMPHOCYTE ACTIVATION; TRICHOPHYTON RUBRUM; TRICHOPHYTON RUBRUM INFECTION; ANIMAL; CASE CONTROL STUDY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MIDDLE AGED; MOUSE; TINEA; TRICHOPHYTON;

TRICHOPHYTON RUBRUM;

ADULT; AGED; ANIMALS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DENDRITIC CELLS; FEMALE; HUMANS; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE; MIDDLE AGED; TINEA; TRICHOPHYTON;

EID: 84910005842     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110879     Document Type: Article

References (25)

1. Weitzman I, Summerbell RC (1995) The dermatophytes. Clin Microbiol Rev 8: 240-259.
2. Seebacher C, Bouchara JP, Mignon B (2008) Updates on the epidemiology of dermatophyte infections. Mycopathologia 166: 335-352.
3. Summerbell RC (1997) Epidemiology and ecology of onychomycosis. Dermatology194 Suppl 1: 32-36.
4. Gruseck E, Abeck D, Ring J (1993) Relapsing severe Trichophyton rubrum infections in an immunocompromised host: evidence of onychomycosis as a source of reinfection based on lectin typing. Mycoses 36: 275-278.
5. Korting HC, Blecher P, Stallmann D, Hamm G (1993) Dermatophytes on the feet of HIV-infected patients: frequency, species distribution, localization and antimicrobial susceptibility. Mycoses 36: 271-274.
6. Erbagci Z (2002) Deep dermatophytoses in association with atopy and diabetes mellitus: Majocchi's granuloma tricophyticum or dermatophytic pseudomycetoma? Mycopathologia 154: 163-169.
7. Dahl MV (1994) Dermatophytosis and the immune response. J Am Acad Dermatol 31: S34-41.
8. Woodfolk JA, Platts-Mills TA (1998) The immune response to dermatophytes. Res Immunol 149: 436-445; discussion 522-433.
9. Hoving JC, Wilson GJ, Brown GD (2014) Signalling C-Type lectin receptors, microbial recognition and immunity. Cell Microbiol 16: 185-194.
10. Romani L (2004) Immunity to fungal infections. Nat Rev Immunol 4: 1-23.
11. Faro-Trindade I, Willment JA, Kerrigan AM, Redelinghuys P, Hadebe S, et al. (2012) Characterisation of innate fungal recognition in the lung. PLoS One 7: e35675.
12. Romani L (2011) Immunity to fungal infections. Nat Rev Immunol 11: 275-288.
13. Romani L (1997) The T cell response against fungal infections. Curr Opin Immunol 9: 484-490.
14. Romani L, Puccetti P, Bistoni F (1997) Interleukin-12 in infectious diseases. Clin Microbiol Rev 10: 611-636.
15. Stevens DA, Walsh TJ, Bistoni F, Cenci E, Clemons KV, et al. (1998) Cytokines and mycoses. Med Mycol 36 Suppl 1: 174-182.
16. Montagnoli C, Bacci A, Bozza S, Gaziano R, Fiorucci S, et al. (2001) The plasticity of dendritic cells at the host/fungal interface. Immunobiology 204: 582-589.
17. Bozza S, Gaziano R, Spreca A, Bacci A, Montagnoli C, et al. (2002) Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J Immunol 168: 1362-1371.
18. Claudia M, Bacci A, Silvia B, Gaziano R, Spreca A, et al. (2002) The interaction of fungi with dendritic cells: implications for Th immunity and vaccination. Curr Mol Med 2: 507-524.
19. Campos MR, Russo M, Gomes E, Almeida SR (2006) Stimulation, inhibition and death of macrophages infected with Trichophyton rubrum. Microbes Infect 8: 372-379.
20. Moulin V, Morgan ME, Eleveld-Trancikova D, Haanen JB, Wielders E, et al. (2012) Targeting dendritic cells with antigen via dendritic cell-associated promoters. Cancer Gene Ther 19: 303-311.
21. Schwingshackl P, Obermoser G, Nguyen VA, Fritsch P, Sepp N, et al. (2012)Distribution and maturation of skin dendritic cell subsets in two forms of cutaneous T-cell lymphoma: mycosis fungoides and Sezary syndrome. Acta Derm Venereol 92: 269-275.
22. Svajger U, Anderluh M, Jeras M, Obermajer N (2010) C-type lectin DC-SIGN: an adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity. Cell Signal 22: 1397-1405.
23. Cambi A, Gijzen K, de Vries l J, Torensma R, Joosten B, et al. (2003) The Ctype lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol 33: 532-538.
24. Sousa Mda G, Reid DM, Schweighoffer E, Tybulewicz V, Ruland J, et al. (2011) Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin. Cell Host Microbe 9: 436-443.
25. Newman SL, Lemen W, Smulian AG (2011) Dendritic cells restrict the transformation of Histoplasma capsulatum conidia into yeasts. Med Mycol 49: 356-364.