Computational approach for designing thermostable Candida antarctica lipase B by molecular dynamics simulation

Journal of Biotechnology

Volumn 192, Issue Part A, 2014, Pages 66-70

  Park, Hyun June ^a   Park, Kyungmoon ^b   Kim, Yong Hwan ^c   Yoo, Young Je ^a  

^a Seoul National University   (South Korea)

^b Hong Ik University   (South Korea)

^c Kwangwoon University   (South Korea)

Author keywords

Candida antarctica lipase B; Enzyme rigidity; Molecular dynamics simulation; Thermostability

Indexed keywords

CANDIDA; COMPUTATIONAL CHEMISTRY; ENZYMES; ISOMERS; REACTION KINETICS; STABILITY; YEAST;

CANDIDA ANTARCTICA LIPASE B; COMPUTATIONAL APPROACH; COMPUTATIONAL DESIGN; INTRAMOLECULAR INTERACTIONS; MOLECULAR DYNAMICS SIMULATIONS; ROOT MEAN SQUARE DEVIATIONS; THERMOSTABILITY; WEAK POINTS;

MOLECULAR DYNAMICS;

LIPASE B; FUNGAL PROTEIN; LIPASE B, CANDIDA ANTARCTICA; TRIACYLGLYCEROL LIPASE;

ALGORITHM; ARTICLE; CANDIDA ANTARCTICA; MOLECULAR DYNAMICS; MUTANT; NONHUMAN; TEMPERATURE; THERMOSTABILITY; CHEMISTRY; ENZYME STABILITY; GENETICS; MUTATION; PICHIA; PLASMID; SITE DIRECTED MUTAGENESIS;

ENZYME STABILITY; FUNGAL PROTEINS; LIPASE; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PICHIA; PLASMIDS; TEMPERATURE;

EID: 84909968239     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.09.014     Document Type: Article

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