Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins

Matrix Biology

Volumn 36, Issue , 2014, Pages 5-14

  Ishikawa, Taichi ^a   Wondimu, Zenebech ^a   Oikawa, Yuko ^a   Ingerpuu, Sulev ^b   Virtanen, Ismo ^c   Patarroyo, Manuel ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF TARTU   (Estonia)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Cell migration; Integrin; Laminin; Monoclonal antibody

Indexed keywords

CD146 ANTIGEN; LAMININ; LAMININ 411; LAMININ 421; LAMININ ALPHA4; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 084; MONOCLONAL ANTIBODY FC10; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 6; LAMA4 PROTEIN, HUMAN; LAMININ 8; LAMININ 9; MCAM PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MELANOMA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; TUMOR CELL; WESTERN BLOTTING; CELL MOTION; GENETICS; IMMUNOLOGY; METABOLISM; NEOPLASM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD146; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; INTEGRIN ALPHA6BETA1; LAMININ; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY;

EID: 84909948417     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2014.03.003     Document Type: Article

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