In Silico assay development for screening of tetracyclic triterpenoids as anticancer agents against human breast cancer cell line MCF7

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Prakash, Om ^a   Ahmad, Ateeque ^a   Tripathi, Vinay Kumar ^b   Tandon, Sudeep ^a   Pant, Aditya Bhusan ^b   Khan, Feroz ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; ANTINEOPLASTIC AGENT; OENA; OENB; OENOTHERANSTROL DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; TRITERPENE;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; INCUBATION TIME; MCF 7 CELL LINE; MOLECULAR DOCKING; MTT ASSAY; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE; BREAST TUMOR; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; FEMALE; INFORMATION PROCESSING; PROCEDURES; REPRODUCIBILITY; THEORETICAL MODEL; WORKFLOW;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; COMPUTER SIMULATION; DATASETS AS TOPIC; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MODELS, THEORETICAL; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES; WORKFLOW;

EID: 84909620020     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111049     Document Type: Article

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