-
1
-
-
79953805191
-
Neural systems governed by nicotinic acetylcholine receptors: Emerging hypotheses
-
Miwa, J. M., Freedman, R., and Lester, H. A. (2011) Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron 70, 20-33
-
(2011)
Neuron
, vol.70
, pp. 20-33
-
-
Miwa, J.M.1
Freedman, R.2
Lester, H.A.3
-
2
-
-
22844432580
-
Neuronal nicotinic acetylcholine receptors: Structural revelations, target identifications, and therapeutic inspirations
-
Jensen, A. A., Frølund, B., Liljefors, T., and Krogsgaard-Larsen, P. (2005) Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. J. Med. Chem. 48, 4705-4745
-
(2005)
J. Med. Chem.
, vol.48
, pp. 4705-4745
-
-
Jensen, A.A.1
Frølund, B.2
Liljefors, T.3
Krogsgaard-Larsen, P.4
-
3
-
-
68349130498
-
Structural and functional diversity of native brain neuronal nicotinic receptors
-
Gotti, C., Clementi, F., Fornari, A., Gaimarri, A., Guiducci, S., Manfredi, I., Moretti, M., Pedrazzi, P., Pucci, L., and Zoli, M. (2009) Structural and functional diversity of native brain neuronal nicotinic receptors. Biochem. Pharmacol. 78, 703-711
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 703-711
-
-
Gotti, C.1
Clementi, F.2
Fornari, A.3
Gaimarri, A.4
Guiducci, S.5
Manfredi, I.6
Moretti, M.7
Pedrazzi, P.8
Pucci, L.9
Zoli, M.10
-
4
-
-
33746238089
-
α4β2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
-
Moroni, M., Zwart, R., Sher, E., Cassels, B. K., and Bermudez, I. (2006) α4β2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine. Mol. Pharmacol. 70, 755-768
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 755-768
-
-
Moroni, M.1
Zwart, R.2
Sher, E.3
Cassels, B.K.4
Bermudez, I.5
-
5
-
-
0037289747
-
Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors
-
Nelson, M. E., Kuryatov, A., Choi, C. H., Zhou, Y., and Lindstrom, J. (2003) Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors. Mol. Pharmacol. 63, 332-341
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 332-341
-
-
Nelson, M.E.1
Kuryatov, A.2
Choi, C.H.3
Zhou, Y.4
Lindstrom, J.5
-
6
-
-
84901948488
-
Pharmacological chaperoning of nAChRs:Atherapeutic target for Parkinson's disease
-
Srinivasan, R., Henderson, B. J., Lester, H. A., and Richards, C. I. (2014) Pharmacological chaperoning of nAChRs:Atherapeutic target for Parkinson's disease. Pharmacol. Res. 83, 20-29
-
(2014)
Pharmacol. Res.
, vol.83
, pp. 20-29
-
-
Srinivasan, R.1
Henderson, B.J.2
Lester, H.A.3
Richards, C.I.4
-
7
-
-
0033136270
-
lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS
-
Miwa, J. M., Ibanez-Tallon, I., Crabtree, G. W., Sánchez, R., Sali, A., Role, L. W., and Heintz, N. (1999) lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron 23, 105-114
-
(1999)
Neuron
, vol.23
, pp. 105-114
-
-
Miwa, J.M.1
Ibanez-Tallon, I.2
Crabtree, G.W.3
Sánchez, R.4
Sali, A.5
Role, L.W.6
Heintz, N.7
-
8
-
-
79953200120
-
NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1
-
Lyukmanova, E. N., Shenkarev, Z. O., Shulepko, M. A., Mineev, K. S., D'Hoedt, D., Kasheverov, I. E., Filkin, S. Y., Krivolapova, A. P., Janickova, H., Dolezal, V., Dolgikh, D. A., Arseniev, A. S., Bertrand, D., Tsetlin, V. I., and Kirpichnikov, M. P. (2011) NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1. J. Biol. Chem. 286, 10618-10627
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 10618-10627
-
-
Lyukmanova, E.N.1
Shenkarev, Z.O.2
Shulepko, M.A.3
Mineev, K.S.4
D'Hoedt, D.5
Kasheverov, I.E.6
Filkin, S.Y.7
Krivolapova, A.P.8
Janickova, H.9
Dolezal, V.10
Dolgikh, D.A.11
Arseniev, A.S.12
Bertrand, D.13
Tsetlin, V.I.14
Kirpichnikov, M.P.15
-
9
-
-
84864921721
-
Optimizing cholinergic tone through lynx modulators of nicotinic receptors: Implications for plasticity and nicotine addiction
-
Miwa, J. M., Lester, H. A., and Walz, A. (2012) Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction. Physiology 27, 187-199
-
(2012)
Physiology
, vol.27
, pp. 187-199
-
-
Miwa, J.M.1
Lester, H.A.2
Walz, A.3
-
10
-
-
0344443178
-
Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda
-
Chimienti, F., Hogg, R. C., Plantard, L., Lehmann, C., Brakch, N., Fischer, J., Huber, M., Bertrand, D., and Hohl, D. (2003) Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum. Mol. Genet. 12, 3017-3024
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3017-3024
-
-
Chimienti, F.1
Hogg, R.C.2
Plantard, L.3
Lehmann, C.4
Brakch, N.5
Fischer, J.6
Huber, M.7
Bertrand, D.8
Hohl, D.9
-
11
-
-
78649442213
-
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex
-
Morishita, H., Miwa, J. M., Heintz, N., and Hensch, T. K. (2010) Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science 330, 1238-1240
-
(2010)
Science
, vol.330
, pp. 1238-1240
-
-
Morishita, H.1
Miwa, J.M.2
Heintz, N.3
Hensch, T.K.4
-
12
-
-
33748081791
-
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo
-
Miwa, J. M., Stevens, T. R., King, S. L., Caldarone, B. J., Ibanez-Tallon, I., Xiao, C., Fitzsimonds, R. M., Pavlides, C., Lester, H. A., Picciotto, M. R., and Heintz, N. (2006) The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron 51, 587-600
-
(2006)
Neuron
, vol.51
, pp. 587-600
-
-
Miwa, J.M.1
Stevens, T.R.2
King, S.L.3
Caldarone, B.J.4
Ibanez-Tallon, I.5
Xiao, C.6
Fitzsimonds, R.M.7
Pavlides, C.8
Lester, H.A.9
Picciotto, M.R.10
Heintz, N.11
-
13
-
-
84868347589
-
Enhancement in motor learning through genetic manipulation of the Lynx1 gene
-
Miwa, J. M., and Walz, A. (2012) Enhancement in motor learning through genetic manipulation of the Lynx1 gene. PLoS One 7, e43302
-
(2012)
PLoS One
, vol.7
, pp. e43302
-
-
Miwa, J.M.1
Walz, A.2
-
14
-
-
63149187256
-
A role for LYNX2 in anxiety-related behavior
-
Tekinay, A. B., Nong, Y., Miwa, J. M., Lieberam, I., Ibanez-Tallon, I., Greengard, P., and Heintz, N. (2009) A role for LYNX2 in anxiety-related behavior. Proc. Natl. Acad. Sci. U.S.A. 106, 4477-4482
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4477-4482
-
-
Tekinay, A.B.1
Nong, Y.2
Miwa, J.M.3
Lieberam, I.4
Ibanez-Tallon, I.5
Greengard, P.6
Heintz, N.7
-
15
-
-
84891390520
-
Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors
-
Henderson, B. J., Srinivasan, R., Nichols, W. A., Dilworth, C. N., Gutierrez, D. F., Mackey, E. D., McKinney, S., Drenan, R. M., Richards, C. I., and Lester, H. A. (2014) Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors. J. Gen. Physiol. 143, 51-66
-
(2014)
J. Gen. Physiol.
, vol.143
, pp. 51-66
-
-
Henderson, B.J.1
Srinivasan, R.2
Nichols, W.A.3
Dilworth, C.N.4
Gutierrez, D.F.5
Mackey, E.D.6
McKinney, S.7
Drenan, R.M.8
Richards, C.I.9
Lester, H.A.10
-
16
-
-
0035972147
-
Rapid cycling of lipid raft markers between the cell surface and Golgi complex
-
Nichols, B. J., Kenworthy, A. K., Polishchuk, R. S., Lodge, R., Roberts, T. H., Hirschberg, K., Phair, R. D., and Lippincott-Schwartz, J. (2001) Rapid cycling of lipid raft markers between the cell surface and Golgi complex. J. Cell Biol. 153, 529-541
-
(2001)
J. Cell Biol.
, vol.153
, pp. 529-541
-
-
Nichols, B.J.1
Kenworthy, A.K.2
Polishchuk, R.S.3
Lodge, R.4
Roberts, T.H.5
Hirschberg, K.6
Phair, R.D.7
Lippincott-Schwartz, J.8
-
17
-
-
4344578072
-
The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP
-
Cha, B., Kenworthy, A., Murtazina, R., and Donowitz, M. (2004) The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP. J. Cell Sci. 117, 3353-3365
-
(2004)
J. Cell Sci.
, vol.117
, pp. 3353-3365
-
-
Cha, B.1
Kenworthy, A.2
Murtazina, R.3
Donowitz, M.4
-
18
-
-
0347064158
-
Assembly of α4β2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain lneurons
-
Nashmi, R., Dickinson, M. E., McKinney, S., Jareb, M., Labarca, C., Fraser, S. E., and Lester, H. A. (2003) Assembly of α4β2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain lneurons. J. Neurosci. 23, 11554-11567
-
(2003)
J. Neurosci.
, vol.23
, pp. 11554-11567
-
-
Nashmi, R.1
Dickinson, M.E.2
McKinney, S.3
Jareb, M.4
Labarca, C.5
Fraser, S.E.6
Lester, H.A.7
-
19
-
-
37349032306
-
Subcellular trafficking, pentameric assembly and subunit stoichiometry of neuronal nicotinic ACh receptors containing fluorescently-labeled α6 and β3 subunits
-
Drenan, R. M., Nashmi, R., Imoukhuede, P., Just, H., McKinney, S., and Lester, H. A. (2008) Subcellular trafficking, pentameric assembly and subunit stoichiometry of neuronal nicotinic ACh receptors containing fluorescently-labeled α6 and β3 subunits. Mol. Pharmacol. 73, 27-41
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 27-41
-
-
Drenan, R.M.1
Nashmi, R.2
Imoukhuede, P.3
Just, H.4
McKinney, S.5
Lester, H.A.6
-
20
-
-
73149090594
-
GABA transporter function, oligomerization state, and anchoring: Correlates with subcellularly resolved FRET
-
Moss, F. J., Imoukhuede, P. I., Scott, K., Hu, J., Jankowsky, J. L., Quick, M. W., and Lester, H. A. (2009) GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET. J. Gen. Physiol. 134, 489-521
-
(2009)
J. Gen. Physiol.
, vol.134
, pp. 489-521
-
-
Moss, F.J.1
Imoukhuede, P.I.2
Scott, K.3
Hu, J.4
Jankowsky, J.L.5
Quick, M.W.6
Lester, H.A.7
-
21
-
-
4043180577
-
Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo
-
Ibañez-Tallon, I., Wen, H., Miwa, J. M., Xing, J., Tekinay, A. B., Ono, F., Brehm, P., and Heintz, N. (2004) Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron 43, 305-311
-
(2004)
Neuron
, vol.43
, pp. 305-311
-
-
Ibañez-Tallon, I.1
Wen, H.2
Miwa, J.M.3
Xing, J.4
Tekinay, A.B.5
Ono, F.6
Brehm, P.7
Heintz, N.8
-
22
-
-
0032500053
-
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
-
Miesenböck, G., De Angelis, D. A., and Rothman, J. E. (1998) Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature 394, 192-195
-
(1998)
Nature
, vol.394
, pp. 192-195
-
-
Miesenböck, G.1
De Angelis, D.A.2
Rothman, J.E.3
-
23
-
-
27744463295
-
A receptors
-
A receptors. J. Neurosci. 25, 10469-10478
-
(2005)
J. Neurosci.
, vol.25
, pp. 10469-10478
-
-
Jacob, T.C.1
Bogdanov, Y.D.2
Magnus, C.3
Saliba, R.S.4
Kittler, J.T.5
Haydon, P.G.6
Moss, S.J.7
-
24
-
-
80052410191
-
Trafficking of α4∗ nicotinic receptors revealed by superecliptic phluorin: Effects of a β4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine
-
Richards, C. I., Srinivasan, R., Xiao, C., Mackey, E. D., Miwa, J. M., and Lester, H. A. (2011) Trafficking of α4∗ nicotinic receptors revealed by superecliptic phluorin: effects of a β4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine. J. Biol. Chem. 286, 31241-31249
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 31241-31249
-
-
Richards, C.I.1
Srinivasan, R.2
Xiao, C.3
Mackey, E.D.4
Miwa, J.M.5
Lester, H.A.6
-
25
-
-
73149107761
-
Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique
-
Khiroug, S. S., Pryazhnikov, E., Coleman, S. K., Jeromin, A., Keinänen, K., and Khiroug, L. (2009) Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique. BMC Neurosci. 10, 141
-
(2009)
BMC Neurosci.
, vol.10
, pp. 141
-
-
Khiroug, S.S.1
Pryazhnikov, E.2
Coleman, S.K.3
Jeromin, A.4
Keinänen, K.5
Khiroug, L.6
-
26
-
-
0037075542
-
Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1
-
Ibañez-Tallon, I., Miwa, J. M., Wang, H. L., Adams, N. C., Crabtree, G. W., Sine, S. M., and Heintz, N. (2002) Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron 33, 893-903
-
(2002)
Neuron
, vol.33
, pp. 893-903
-
-
Ibañez-Tallon, I.1
Miwa, J.M.2
Wang, H.L.3
Adams, N.C.4
Crabtree, G.W.5
Sine, S.M.6
Heintz, N.7
-
27
-
-
0031780511
-
Agonist-induced up-regulation of α4β2 nicotinic acetylcholine receptors in M10 cells: Pharmacological and spatial definition
-
Whiteaker, P., Sharples, C. G., and Wonnacott, S. (1998) Agonist-induced up-regulation of α4β2 nicotinic acetylcholine receptors in M10 cells: pharmacological and spatial definition. Mol. Pharmacol. 53, 950-962
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 950-962
-
-
Whiteaker, P.1
Sharples, C.G.2
Wonnacott, S.3
-
29
-
-
70349850556
-
Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the α7 acetylcholine receptor through a cytoplasmic coiled-coil domain
-
Wang, Y., Yao, Y., Tang, X. Q., and Wang, Z. Z. (2009) Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the α7 acetylcholine receptor through a cytoplasmic coiled-coil domain. J. Neurosci. 29, 12625-12635
-
(2009)
J. Neurosci.
, vol.29
, pp. 12625-12635
-
-
Wang, Y.1
Yao, Y.2
Tang, X.Q.3
Wang, Z.Z.4
-
30
-
-
77955409154
-
Ric-3 promotes α7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites
-
Alexander, J. K., Sagher, D., Krivoshein, A. V., Criado, M., Jefford, G., and Green, W. N. (2010) Ric-3 promotes α7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites. J. Neurosci. 30, 10112-10126
-
(2010)
J. Neurosci.
, vol.30
, pp. 10112-10126
-
-
Alexander, J.K.1
Sagher, D.2
Krivoshein, A.V.3
Criado, M.4
Jefford, G.5
Green, W.N.6
-
31
-
-
65549132734
-
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry: Implications for drug discovery
-
Lester, H. A., Xiao, C., Srinivasan, R., Son, C. D., Miwa, J., Pantoja, R., Banghart, M. R., Dougherty, D. A., Goate, A. M., and Wang, J. C. (2009) Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry: implications for drug discovery. AAPS J. 11, 167-177
-
(2009)
AAPS J.
, vol.11
, pp. 167-177
-
-
Lester, H.A.1
Xiao, C.2
Srinivasan, R.3
Son, C.D.4
Miwa, J.5
Pantoja, R.6
Banghart, M.R.7
Dougherty, D.A.8
Goate, A.M.9
Wang, J.C.10
-
32
-
-
34547651077
-
Chronic nicotine cell specifically upregulates functional α4∗ nicotinic receptors: Basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path
-
Nashmi, R., Xiao, C., Deshpande, P., McKinney, S., Grady, S. R., Whiteaker, P., Huang, Q., McClure-Begley, T., Lindstrom, J. M., Labarca, C., Collins, A. C., Marks, M. J., and Lester, H. A. (2007) Chronic nicotine cell specifically upregulates functional α4∗ nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J. Neurosci. 27, 8202-8218
-
(2007)
J. Neurosci.
, vol.27
, pp. 8202-8218
-
-
Nashmi, R.1
Xiao, C.2
Deshpande, P.3
McKinney, S.4
Grady, S.R.5
Whiteaker, P.6
Huang, Q.7
McClure-Begley, T.8
Lindstrom, J.M.9
Labarca, C.10
Collins, A.C.11
Marks, M.J.12
Lester, H.A.13
-
33
-
-
78650873492
-
Nicotine upregulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
-
Srinivasan, R., Pantoja, R., Moss, F. J., Mackey, E. D., Son, C. D., Miwa, J., and Lester, H. A. (2011) Nicotine upregulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning. J. Gen. Physiol. 137, 59-79
-
(2011)
J. Gen. Physiol.
, vol.137
, pp. 59-79
-
-
Srinivasan, R.1
Pantoja, R.2
Moss, F.J.3
Mackey, E.D.4
Son, C.D.5
Miwa, J.6
Lester, H.A.7
-
34
-
-
84892176557
-
Efficacy and safety of the alpha7 agonist ABT-126 in mild-to-moderate Alzheimer's dementia
-
Gault, L., Ritchie, C., Robieson, W., Pritchett, Y., Othman, A., and Lenz, R. (2013) Efficacy and safety of the alpha7 agonist ABT-126 in mild-to-moderate Alzheimer's dementia. Alzheimer's Dementia 9, 138
-
(2013)
Alzheimer's Dementia
, vol.9
, pp. 138
-
-
Gault, L.1
Ritchie, C.2
Robieson, W.3
Pritchett, Y.4
Othman, A.5
Lenz, R.6
-
35
-
-
68349148342
-
TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia
-
Hauser, T. A., Kucinski, A., Jordan, K. G., Gatto, G. J., Wersinger, S. R., Hesse, R. A., Stachowiak, E. K., Stachowiak, M. K., Papke, R. L., Lippiello, P. M., and Bencherif, M. (2009) TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia. Biochem. Pharmacol. 78, 803-812
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 803-812
-
-
Hauser, T.A.1
Kucinski, A.2
Jordan, K.G.3
Gatto, G.J.4
Wersinger, S.R.5
Hesse, R.A.6
Stachowiak, E.K.7
Stachowiak, M.K.8
Papke, R.L.9
Lippiello, P.M.10
Bencherif, M.11
-
36
-
-
84878590414
-
Arandomized exploratory trial of an alpha-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia
-
Lieberman, J. A., Dunbar, G., Segreti, A. C., Girgis, R. R., Seoane, F., Beaver, J. S., Duan, N., and Hosford, D. A. (2013)Arandomized exploratory trial of an alpha-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia. Neuropsychopharmacology 38, 968-975
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 968-975
-
-
Lieberman, J.A.1
Dunbar, G.2
Segreti, A.C.3
Girgis, R.R.4
Seoane, F.5
Beaver, J.S.6
Duan, N.7
Hosford, D.A.8
-
37
-
-
84855964150
-
EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
-
Prickaerts, J., van Goethem, N. P., Chesworth, R., Shapiro, G., Boess, F. G., Methfessel, C., Reneerkens, O. A., Flood, D. G., Hilt, D., Gawryl, M., Bertrand, S., Bertrand, D., and König, G. (2012) EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Neuropharmacology 62, 1099-1110
-
(2012)
Neuropharmacology
, vol.62
, pp. 1099-1110
-
-
Prickaerts, J.1
Van Goethem, N.P.2
Chesworth, R.3
Shapiro, G.4
Boess, F.G.5
Methfessel, C.6
Reneerkens, O.A.7
Flood, D.G.8
Hilt, D.9
Gawryl, M.10
Bertrand, S.11
Bertrand, D.12
König, G.13
-
38
-
-
34548689531
-
An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo
-
Timmermann, D. B., Grønlien, J. H., Kohlhaas, K. L., Nielsen, E. Ø., Dam, E., Jørgensen, T. D., Ahring, P. K., Peters, D., Holst, D., Christensen, J. K., Malysz, J., Briggs, C. A., Gopalakrishnan, M., and Olsen, G. M. (2007) An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. J. Pharmacol. Exp. Ther. 323, 294-307
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.323
, pp. 294-307
-
-
Timmermann, D.B.1
Grønlien, J.H.2
Kohlhaas, K.L.3
Nielsen, E.O.4
Dam, E.5
Jørgensen, T.D.6
Ahring, P.K.7
Peters, D.8
Holst, D.9
Christensen, J.K.10
Malysz, J.11
Briggs, C.A.12
Gopalakrishnan, M.13
Olsen, G.M.14
-
39
-
-
84909600750
-
Positive allosteric modulators of the alpha 7 nicotinic acetylcholine receptor and uses thereof
-
January 30, U. S. Patent
-
Harvey, A., Fluck, A., Giethlen, B., Paul, D., and Schaeffer, L. (January 30, 2014) Positive allosteric modulators of the alpha 7 nicotinic acetylcholine receptor and uses thereof. U. S. Patent 20,140,031,395 A1
-
(2014)
-
-
Harvey, A.1
Fluck, A.2
Giethlen, B.3
Paul, D.4
Schaeffer, L.5
-
40
-
-
84909629830
-
α-7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof
-
July 29, U. S. Patent
-
Kanner, R. (July 29, 2010) α-7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof. U. S. Patent 20,100,190,819 A1
-
(2010)
-
-
Kanner, R.1
-
41
-
-
84909584145
-
Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof
-
November 14, WO
-
Putman, D., and Dasse, O. (November 14, 2013) Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof. WO 2013169889 A1
-
(2013)
-
-
Putman, D.1
Dasse, O.2
-
42
-
-
2542432136
-
Cys-loop receptors: New twists and turns
-
Lester, H. A., Dibas, M. I., Dahan, D. S., Leite, J. F., and Dougherty, D. A. (2004) Cys-loop receptors: new twists and turns. Trends Neurosci. 27, 329-336
-
(2004)
Trends Neurosci.
, vol.27
, pp. 329-336
-
-
Lester, H.A.1
Dibas, M.I.2
Dahan, D.S.3
Leite, J.F.4
Dougherty, D.A.5
-
43
-
-
0035869342
-
Chronic exposure to nicotine upregulates the human α4β2 nicotinic acetylcholine receptor function
-
Buisson, B., and Bertrand, D. (2001) Chronic exposure to nicotine upregulates the human α4β2 nicotinic acetylcholine receptor function. J. Neurosci. 21, 1819-1829
-
(2001)
J. Neurosci.
, vol.21
, pp. 1819-1829
-
-
Buisson, B.1
Bertrand, D.2
|